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Rigshospitalet - a part of Copenhagen University Hospital
  1. 2018
  2. Published

    Reduced risk of heart failure with intensified multifactorial intervention in individuals with type 2 diabetes and microalbuminuria: 21 years of follow-up in the randomised Steno-2 study

    Oellgaard, J., Gæde, P., Rossing, P., Rørth, R., Køber, L., Parving, H-H. & Pedersen, O. Aug 2018 In : Diabetologia. 61, 8, p. 1724-1733 9 p.

    Research output: Contribution to journalJournal article

  3. Published

    Higher Collagen VI Formation Is Associated With All-Cause Mortality in Patients With Type 2 Diabetes and Microalbuminuria

    Rasmussen, D. G. K., Hansen, T. W., von Scholten, B. J., Nielsen, S. H., Reinhard, H., Parving, H-H., Tepel, M., Karsdal, M. A., Jacobsen, P. K., Genovese, F. & Rossing, P. Jul 2018 In : Diabetes Care. 41, 7, p. 1493-1500 7 p.

    Research output: Contribution to journalJournal article

  4. Published

    Effect of Insulin Analogs on Frequency of Non-Severe Hypoglycemia in Patients with Type 1 Diabetes Prone to Severe Hypoglycemia: Much Higher Rates Detected by Continuous Glucose Monitoring than by Self-Monitoring of Blood Glucose-The HypoAna Trial

    Agesen, R. M., Kristensen, P. L., Beck-Nielsen, H., Nørgaard, K., Perrild, H., Jensen, T., Parving, H-H., Thorsteinsson, B., Tarnow, L. & Pedersen-Bjergaard, U. 1 Mar 2018 In : Diabetes Technology and Therapeutics. 20, 3

    Research output: Contribution to journalJournal article

  5. Published

    Three-question set from Michigan Neuropathy Screening Instrument adds independent prognostic information on cardiovascular outcomes: analysis of ALTITUDE trial

    Seferovic, J. P., Pfeffer, M. A., Claggett, B., Desai, A. S., de Zeeuw, D., Haffner, S. M., McMurray, J. J. V., Parving, H-H., Solomon, S. D. & Chaturvedi, N. Mar 2018 In : Diabetologia. 61, 3, p. 581-588 7 p.

    Research output: Contribution to journalJournal article

  6. Published

    Biomarkers of inflammation and endothelial dysfunction as predictors of pulse pressure and incident hypertension in type 1 diabetes: a 20 year life-course study in an inception cohort

    Ferreira, I., Hovind, P., Schalkwijk, C. G., Parving, H-H., Stehouwer, C. D. A. & Rossing, P. Jan 2018 In : Diabetologia. 61, 1, p. 231-241 10 p.

    Research output: Contribution to journalJournal article

  7. Published

    Growth differentiation factor-15 and fibroblast growth factor-23 are associated with mortality in type 2 diabetes - An observational follow-up study

    Frimodt-Møller, M., von Scholten, B. J., Reinhard, H., Jacobsen, P. K., Hansen, T. W., Persson, F. I., Parving, H-H. & Rossing, P. 2018 In : P L o S One. 13, 4, p. e0196634

    Research output: Contribution to journalJournal article

  8. 2017
  9. Published

    Fasting Plasma Trimethylamine-N-Oxide as a Risk Marker of Poor Renal Outcomes, Cardiovascular Disease, and Mortality in Patients with Type 1 Diabetes with Diabetic Nephropathy

    Winther, S. A., Øllgaard, J. C., Parving, H-H. D., Hazen, S. L., Pedersen, O. & Rossing, P. 4 Nov 2017 1 p.

    Research output: Contribution to conferenceConference abstract for conference

  10. Published

    Symmetric and Asymmetric Dimethylarginine as Risk Markers of Cardiovascular Disease, All-Cause Mortality, and Deterioration in Kidney Function in Patients with Type 2 Diabetes and Microalbuminuria

    Persson, F., Zobel, E. H., von Scholten, B. J., Hansen, T. W., Parving, H-H. D. & Rossing, P. 4 Nov 2017 1 p.

    Research output: Contribution to conferenceConference abstract for conference

  11. Published

    A Novel Marker of Collagen Type VI Formation Is Prognostic for Cardiovascular Disease, All-Cause Mortality, and Deterioration of Kidney Function in Patients with Type 2 Diabetes with Microalbuminuria

    Guldager, D. K. R., Hansen, T. W., Nielsen, S. H., Reinhard, H., Parving, H-H. D., Karsdal, M. A., Genovese, F. & Rossing, P. 3 Nov 2017 1 p.

    Research output: Contribution to conferenceConference abstract for conference

  12. Published

    Collagen Type III Degradation Is Associated with Deterioration of Kidney Function in Patients with Type 2 Diabetes with Microalbuminuria

    Genovese, F., Hansen, T. W., Guldager, D. K. R., Nielsen, S. H., Reinhard, H., Parving, H-H. D., Karsdal, M. A. & Rossing, P. 3 Nov 2017 1 p.

    Research output: Contribution to conferenceConference abstract for conference

  13. Published

    GDF-15 and FGF-23 Are Associated with Mortality in Type 2 Diabetic Patients with Microalbuminuria

    Frimodt-Møller, M., von Scholten, B. J., Reinhard, H., Hansen, T. W., Persson, F., Parving, H-H. D. & Rossing, P. 3 Nov 2017 1 p.

    Research output: Contribution to conferenceConference abstract for conference

  14. Published

    Is Urinary KIM-1 a Predictor of EGFR Decline, Incident Cardiovascular Disease, and All Cause Mortality?

    Eickhoff, M. K., von Scholten, B. J., Reinhard, H., Hansen, T. W., Persson, F., Parving, H-H. D. & Rossing, P. 3 Nov 2017 1 p.

    Research output: Contribution to conferenceConference abstract for conference

  15. Published

    Plasma high-sensitivity troponin T predicts end-stage renal disease and cardiovascular and all-cause mortality in patients with type 1 diabetes and diabetic nephropathy

    Galsgaard, J., Persson, F., Hansen, T. W., Jorsal, A., Tarnow, L., Parving, H-H. & Rossing, P. Nov 2017 In : Kidney International. 92, 5, p. 1242-1248 6 p.

    Research output: Contribution to journalJournal article

  16. Published

    Urinary proteomics predict onset of microalbuminuria in normoalbuminuric type 2 diabetic patients, a sub-study of the DIRECT-Protect 2 study

    Lindhardt, M., Persson, F. I., Zürbig, P., Stalmach, A., Mischak, H., de Zeeuw, D., Lambers Heerspink, H., Klein, R., Orchard, T., Porta, M., Fuller, J., Bilous, R., Chaturvedi, N., Parving, H-H. & Rossing, P. Nov 2017 In : Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 32, 11, p. 1866-1873 7 p.

    Research output: Contribution to journalJournal article

  17. Published

    ESRD After Heart Failure, Myocardial Infarction, or Stroke in Type 2 Diabetic Patients With CKD

    Charytan, D. M., Solomon, S. D., Ivanovich, P., Remuzzi, G., Cooper, M. E., McGill, J. B., Parving, H-H., Parfrey, P., Singh, A. K., Burdmann, E. A., Levey, A. S., de Zeeuw, D., Eckardt, K-U., McMurray, J. J. V., Claggett, B., Lewis, E. F. & Pfeffer, M. A. Oct 2017 In : American journal of kidney diseases : the official journal of the National Kidney Foundation. 70, 4, p. 522-531 10 p.

    Research output: Contribution to journalJournal article

  18. Published

    Toe-brachial index as a predictor of cardiovascular disease and all-cause mortality in people with type 2 diabetes and microalbuminuria

    Zobel, E. H., von Scholten, B. J., Reinhard, H., Persson, F., Hansen, T. W., Parving, H. H., Jacobsen, P. K. & Rossing, P. Oct 2017 In : Diabetologia. 60, 10, p. 1883-1891 8 p.

    Research output: Contribution to journalJournal article

  19. Published

    Risk of heart failure in intensively treated patients with type 2 diabetes and microalbuminuria: 21 years follow-up in the multifactorial Steno-2 intervention

    Øllgaard, J. C., Gæde, P., Rørth, R., Rossing, P., Køber, L., Parving, H-H. D. & Pedersen, O. 13 Sep 2017 1 p.

    Research output: Contribution to conferenceConference abstract for conference

  20. Published

    GDF-15 and FGF-23 are associated with mortality in type 2 diabetic patients with microalbuminuria

    Frimodt-Møller, M., von Scholten, B. J., Reinhard, H., Hansen, T. W., Persson, F., Parving, H-H. D. & Rossing, P. 12 Sep 2017 1 p.

    Research output: Contribution to conferenceConference abstract for conference

  21. Published

    Higher plasma methylglyoxal levels are associated with incident cardiovascular disease in individuals with type 1 diabetes: a 12-year follow-up study

    Hanssen, N. M. J., Scheijen, J. L. J., Jorsal, A., Parving, H-H., Tarnow, L., Rossing, P., Stehouwer, C. D. A. & Schalkwijk, C. G. 1 Sep 2017 In : Diabetologia. 60, 1, p. S511 1 p.

    Research output: Contribution to journalJournal article

  22. Published

    Symmetric and asymmetric dimethylarginine as risk markers of cardiovascular disease, all-cause mortality and deterioration in kidney function in persons with type 2 diabetes and microalbuminuria

    Zobel, E. H., von Scholten, B. J., Reinhard, H., Persson, F., Teerlink, T., Hansen, T. W., Parving, H-H., Jacobsen, P. K. & Rossing, P. 11 Jul 2017 In : Cardiovascular Diabetology. 16, 1, p. e88

    Research output: Contribution to journalJournal article

  23. Published

    Incident microalbuminuria and complement factor mannan-binding lectin-associated protein 19 in people with newly diagnosed type 1 diabetes

    Ostergaard, J. A., Thiel, S., Hoffmann-Petersen, I. T., Hovind, P., Parving, H-H., Tarnow, L., Rossing, P. & Hansen, T. K. Apr 2017 In : Diabetes - Metabolism: Research and Reviews (Online). 33, 5, p. e2895

    Research output: Contribution to journalJournal article

  24. Published

    Intensified multifactorial intervention in type 2 diabetics with microalbuminuria leads to long-term renal benefits

    Oellgaard, J., Gaede, P., Rossing, P., Persson, F., Parving, H-H. & Pedersen, O. Apr 2017 In : Kidney International. 91, 4, p. 982-988 7 p.

    Research output: Contribution to journalJournal article

  25. Published

    Longitudinal Estimated GFR Trajectories in Patients With and Without Type 2 Diabetes and Nephropathy

    Weldegiorgis, M., de Zeeuw, D., Li, L., Parving, H-H., Hou, F. F., Remuzzi, G., Greene, T. & Heerspink, H. J. L. Jan 2017 In : American journal of kidney diseases : the official journal of the National Kidney Foundation. 71, 1, p. 91-101 11 p.

    Research output: Contribution to journalJournal article

  26. Published

    Circulating matrix metalloproteinases are associated with arterial stiffness in patients with type 1 diabetes: pooled analysis of three cohort studies

    Peeters, S. A., Engelen, L., Buijs, J., Chaturvedi, N., Fuller, J. H., Jorsal, A., Parving, H-H., Tarnow, L., Theilade, S., Rossing, P., Schalkwijk, C. G. & Stehouwer, C. D. A. 2017 In : Cardiovascular Diabetology. 16, 1, p. e139

    Research output: Contribution to journalJournal article

  27. Published

    Comparing effects of insulin analogues and human insulin on nocturnal glycaemia in hypoglycaemia-prone people with Type 1 diabetes

    Kristensen, P. L., Tarnow, L., Bay, C., Nørgaard, K., Jensen, T., Parving, H-H., Perrild, H., Beck-Nielsen, H., Christiansen, J. S., Thorsteinsson, B. & Pedersen-Bjergaard, U. 2017 In : Diabetic Medicine. 34, 5, p. 625-631

    Research output: Contribution to journalJournal article

  28. Published

    Comparison of exposure response relationship of atrasentan between North American and Asian populations

    Heerspink, H. J. L., Makino, H., Andress, D., Brennan, J. J., Correa-Rotter, R., Coll, B., Davis, J. W., Idler, K., Kohan, D. E., Liu, M., Perkovic, V., Remuzzi, G., Tobe, S. W., Toto, R., Parving, H-H. & de Zeeuw, D. 2017 In : Diabetes, Obesity and Metabolism. 19, 4, p. 545-552

    Research output: Contribution to journalJournal article

  29. Published

    Epicardial, pericardial and total cardiac fat and cardiovascular disease in type 2 diabetic patients with elevated urinary albumin excretion rate

    Christensen, R. H., von Scholten, B. J., Hansen, C. S., Heywood, S. E., Rosenmeier, J. B., Andersen, U. B., Hovind, P., Reinhard, H., Parving, H-H., Pedersen, B. K., Jørgensen, M. E., Jacobsen, P. K. & Rossing, P. 2017 In : European journal of preventive cardiology. 24, 14, p. 1517-1524

    Research output: Contribution to journalJournal article

  30. Published

    Higher Plasma Methylglyoxal Levels are Associated with Incident Cardiovascular Disease in Individuals with Type 1 Diabetes: a 12-Year Follow-Up Study

    Hanssen, N. M. J., Scheijen, J. L. J. M., Jorsal, A., Parving, H-H., Tarnow, L., Rossing, P., Stehouwer, C. D. A. & Schalkwijk, C. G. 2017 In : Diabetes. 66, 8, p. 2278-83

    Research output: Contribution to journalJournal article

  31. Published

    Longitudinal Assessment of the Effect of Atrasentan on Thoracic Bioimpedance in Diabetic Nephropathy: A Randomized, Double-Blind, Placebo-Controlled Trial

    Webb, D. J., Coll, B., Heerspink, H. J. L., Andress, D., Pritchett, Y., Brennan, J. J., Houser, M., Correa-Rotter, R., Kohan, D., Makino, H., Perkovic, V., Remuzzi, G., Tobe, S. W., Toto, R., Busch, R., Pergola, P., Parving, H-H. & de Zeeuw, D. 2017 In : Drugs in R&D. 17, 3, p. 441-448 8 p.

    Research output: Contribution to journalJournal article

  32. Published

    Plasma matrix metalloproteinases are associated with incident cardiovascular disease and all-cause mortality in patients with type 1 diabetes: a 12-year follow-up study

    Peeters, S. A., Engelen, L., Buijs, J., Jorsal, A., Parving, H-H., Tarnow, L., Rossing, P., Schalkwijk, C. G. & Stehouwer, C. D. A. 2017 In : Cardiovascular Diabetology. 16, 1, p. e55

    Research output: Contribution to journalJournal article

  33. Published

    The effects of atrasentan on urinary metabolites in patients with type 2 diabetes and nephropathy

    Pena, M. J., de Zeeuw, D., Andress, D., Brennan, J. J., Correa-Rotter, R., Coll, B., Kohan, D. E., Makino, H., Perkovic, V., Remuzzi, G., Tobe, S. W., Toto, R., Parving, H-H., Sharma, S., Corringham, T., Sharma, K. & Heerspink, H. J. 2017 In : Diabetes, Obesity and Metabolism Online. 19, 5, p. 749-753

    Research output: Contribution to journalJournal article

  34. Published

    The potential for improvement of outcomes by personalized insulin treatment of type 1 diabetes as assessed by analysis of single-patient data from a randomized controlled cross-over insulin trial

    Pedersen-Bjergaard, U., Kristensen, P. L., Beck-Nielsen, H., Nørgaard, K., Perrild, H., Christiansen, J. S., Jensen, T., Parving, H-H., Thorsteinsson, B. & Tarnow, L. 2017 In : Diabetes research and clinical practice. 123, p. 143-148

    Research output: Contribution to journalJournal article

  35. 2016
  36. Published

    Empagliflozin and Progression of Kidney Disease in Type 2 Diabetes

    Parving, H-H., Lambers-Heerspink, H. & de Zeeuw, D. 3 Nov 2016 In : The New England journal of medicine. 375, 18, p. 1800-1 2 p.

    Research output: Contribution to journalLetter

  37. Published

    Determining the Optimal Protocol for Measuring an Albuminuria Class Transition in Clinical Trials in Diabetic Kidney Disease

    Kröpelin, T. F., de Zeeuw, D., Remuzzi, G., Bilous, R., Parving, H-H. & Heerspink, H. J. L. Nov 2016 In : Journal of the American Society of Nephrology : JASN. 27, 11, p. 3405-3412 8 p.

    Research output: Contribution to journalJournal article

  38. Published

    Years of life gained by multifactorial intervention in patients with type 2 diabetes mellitus and microalbuminuria: 21 years follow-up on the Steno-2 randomised trial

    Gæde, P., Øllgaard, J. C., Carstensen, B., Rossing, P., Lund-Andersen, H., Parving, H-H. & Pedersen, O. Nov 2016 In : Diabetologia. 59, 11, p. 2298-307 10 p.

    Research output: Contribution to journalJournal article

  39. Published

    Serum metabolites predict response to angiotensin II receptor blockers in patients with diabetes mellitus

    Pena, M. J., Heinzel, A., Rossing, P., Parving, H-H., Dallmann, G., Rossing, K., Andersen, S., Mayer, B. & Heerspink, H. J. L. 5 Jul 2016 In : Journal of Translational Medicine. 14, 1, p. 203

    Research output: Contribution to journalJournal article

  40. Published

    Prevention of microalbuminuria using early intervention with renin-angiotensin system inhibitors in patients with type 2 diabetes: A systematic review

    Persson, F. I., Lindhardt, M., Rossing, P. & Parving, H-H. Jul 2016 In : Journal of the renin-angiotensin-aldosterone system : JRAAS. 17, 3, p. pii: 1470320316652047

    Research output: Contribution to journalJournal article

  41. Published

    Urinary biomarkers are associated with incident cardiovascular disease, all-cause mortality and deterioration of kidney function in type 2 diabetic patients with microalbuminuria

    von Scholten, B. J., Reinhard, H., Hansen, T. W., Oellgaard, J. C., Parving, H-H., Jacobsen, P. K. & Rossing, P. Jul 2016 In : Diabetologia. 59, 7, p. 1549-57 9 p.

    Research output: Contribution to journalJournal article

  42. Published

    Renal outcomes with aliskiren in patients with type 2 diabetes: a prespecified secondary analysis of the ALTITUDE randomised controlled trial

    Heerspink, H. J. L., Persson, F., Brenner, B. M., Chaturvedi, N., Brunel, P., McMurray, J. J., Desai, A. S., Solomon, S. D., Pfeffer, M. A., Parving, H-H. & de Zeeuw, D. Apr 2016 In : The Lancet Diabetes and Endocrinology. 4, 4, p. 309-17 9 p.

    Research output: Contribution to journalJournal article

  43. Published

    Is a reduction in albuminuria associated with renal and cardiovascular protection?: A post hoc analysis of the ALTITUDE trial

    Heerspink, H. J. L., Ninomiya, T., Persson, F., Brenner, B. M., Brunel, P., Chaturvedi, N., Desai, A. S., Haffner, S. M., Mcmurray, J. J. V., Solomon, S. D., Pfeffer, M. A., Parving, H-H. & de Zeeuw, D. Feb 2016 In : Diabetes, Obesity and Metabolism. 18, 2, p. 169-77 9 p.

    Research output: Contribution to journalJournal article

  44. Published

    Early renin-angiotensin system intervention is more beneficial than late intervention in delaying end-stage renal disease in patients with type 2 diabetes

    Schievink, B., Kröpelin, T., Mulder, S., Parving, H-H., Remuzzi, G., Dwyer, J., Vemer, P., de Zeeuw, D. & Lambers Heerspink, H. J. Jan 2016 In : Diabetes, Obesity and Metabolism. 18, 1, p. 64-71 8 p.

    Research output: Contribution to journalJournal article

  45. Published

    Are human endogenous retroviruses triggers of autoimmune diseases?: Unveiling associations of three diseases and viral loci

    Nexø, B. A., Villesen, P., Nissen, K. K., Lindegaard, H. M., Rossing, P., Petersen, T., Tarnow, L., Hansen, B., Lorenzen, T., Hørslev-Petersen, K., Jensen, S. B., Bahrami, S., Lajer, M., Schmidt, K., Parving, H-H. D., Junker, P. & Laska, M. J. 2016 In : Immunologic Research. 64, 1, p. 55-63

    Research output: Contribution to journalJournal article

  46. Published

    Effect of insulin analogues on frequency of non-severe hypoglycaemia in patients with type 1 diabetes prone to severe hypoglycaemia: The HypoAna trial

    Agesen, R. M., Kristensen, P. L., Beck-Nielsen, H., Nørgaard, K., Perrild, H., Christiansen, J. S., Jensen, T. J., Hougaard, P., Parving, H. H., Thorsteinsson, B., Tarnow, L. & Pedersen-Bjergaard, U. 2016 In : Diabetes & Metabolism. 42, 4, p. 249-55

    Research output: Contribution to journalJournal article

  47. Published

    High osteoprotegerin is associated with development of foot ulcer in type 1 diabetes

    Zobel, E. H., von Scholten, B. J., Lajer, M., Jorsal, A., Tarnow, L., Rasmussen, L. M., Holstein, P., Parving, H-H., Hansen, T. W. & Rossing, P. 2016 In : Journal of Diabetes and its Complications. 30, 8, p. 1603-08

    Research output: Contribution to journalJournal article

  48. Published
  49. Published

    Prediction of the effect of atrasentan on renal and heart failure outcomes based on short-term changes in multiple risk markers

    Schievink, B., de Zeeuw, D., Smink, P. A., Andress, D., Brennan, J. J., Coll, B., Correa-Rotter, R., Hou, F. F., Kohan, D., Kitzman, D. W., Makino, H., Parving, H-H., Perkovic, V., Remuzzi, G., Tobe, S., Toto, R., Hoekman, J. & Lambers Heerspink, H. J. 2016 In : European journal of preventive cardiology. 23, 7, p. 758-68

    Research output: Contribution to journalJournal article

  50. Published

    Renin angiotensin system blockade reduces urinary levels of soluble urokinase plasminogen activator receptor (suPAR) in patients with type 2 diabetes

    Persson, F., Theilade, S., Eugen-Olsen, J., Rossing, P. & Parving, H-H. 2016 In : Journal of Diabetes and its Complications. 30, 8, p. 1440-42

    Research output: Contribution to journalJournal article

  51. 2015
  52. Published

    Increased All-Cause Mortality in Patients With Type 1 Diabetes and High-Expression Mannan-Binding Lectin Genotypes: A 12-Year Follow-up Study

    Østergaard, J. A., Thiel, S., Lajer, M., Steffensen, R., Parving, H-H., Flyvbjerg, A., Rossing, P., Tarnow, L. & Hansen, T. K. Oct 2015 In : Diabetes Care. 38, 10, p. 1898-903 6 p.

    Research output: Contribution to journalJournal article

  53. Published

    Predictors of Atrasentan-Associated Fluid Retention and Change in Albuminuria in Patients with Diabetic Nephropathy

    Kohan, D. E., Lambers Heerspink, H. J., Coll, B., Andress, D., Brennan, J. J., Kitzman, D. W., Correa-Rotter, R., Makino, H., Perkovic, V., Hou, F. F., Remuzzi, G., Tobe, S. W., Toto, R., Parving, H-H. & de Zeeuw, D. 4 Sep 2015 In : Clinical journal of the American Society of Nephrology : CJASN. 10, 9, p. 1568-74 7 p.

    Research output: Contribution to journalJournal article

  54. Published

    IGFBP-4 fragments as markers of cardiovascular mortality in type 1 diabetes patients with and without nephropathy

    Hjortebjerg, R., Tarnow, L., Jorsal, A., Parving, H-H. D., Rossing, P., Bjerre, M. & Frystyk, J. 5 Jun 2015 In : The Journal of clinical endocrinology and metabolism. 100, 8, p. 3032-40

    Research output: Contribution to journalJournal article

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