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Rigshospitalet - a part of Copenhagen University Hospital
Hanne Frederiksen

Hanne Frederiksen

MSc, PhD

Afdeling for Vækst og Reproduktion, GR-5064 Rigshospitalet, Københavns Universitets Hospital Blegdamsvej 9, 2100 København Ø

Building: afsnit 5071, rum 7314A

2100 Kønenhavn Ø

Denmark

Phone: +45 35456359
  1. 2021
  2. Published

    Associations of serum phthalate metabolites with thyroid hormones in GraMo cohort, Southern Spain

    Donat-Vargas, C., Perez-Carrascosa, F., Gomez-Peña, C., Mustieles, V., Salcedo-Bellido, I., Frederiksen, H., Åkesson, A. & Arrebola, J. P., 15 Oct 2021, In: Environmental pollution (Barking, Essex : 1987). 287, p. 117606 117606.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    The effects of selected inhibitors on human fetal adrenal steroidogenesis differs under basal and ACTH-stimulated conditions

    Melau, C., Riis, M. L., Nielsen, J. E., Perlman, S., Lundvall, L., Thuesen, L. L., Hare, K. J., Hammerum, M. S., Mitchell, R. T., Frederiksen, H., Juul, A. & Jørgensen, A., 8 Sep 2021, In: BMC Medicine. 19, 1, p. 204 204.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published
  5. Published

    Prenatal Exposure to Butyl Paraben Is Associated With Fat Percentage in 7-Year-Old Boys

    Højsager, F. D., Kyhl, H. B., Frederiksen, H., Juul, A., Andersson, A-M., Andersen, M. S., Grøntved, A. & Jensen, T. K., 16 Jun 2021, In: The Journal of clinical endocrinology and metabolism. 106, 7, p. e2633-e2638

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Prenatal paraben exposure and anogenital distance and reproductive hormones during mini-puberty: A study from the Odense Child Cohort

    Jensen, T. K., Andersson, A-M., Main, K. M., Johannsen, T. H., Andersen, M. S., Kyhl, H. B., Juul, A. & Frederiksen, H., 15 May 2021, In: Science of the Total Environment. 769, p. 145119

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Associations between Prenatal Exposure to Phthalates and Timing of Menarche and Growth and Adiposity into Adulthood: A Twenty-Years Birth Cohort Study

    Berman, Y. E., Doherty, D. A., Main, K. M., Frederiksen, H., Hickey, M., Keelan, J. A., Newnham, J. P. & Hart, R. J., May 2021, In: International Journal of Environmental Research and Public Health. 18, 9, 4725.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    The influence of prenatal exposure to phthalates on subsequent male growth and body composition in adolescence

    Berman, Y. E., Doherty, D. A., Main, K. M., Frederiksen, H., Keelan, J. A., Newnham, J. P. & Hart, R. J., Apr 2021, In: Environmental Research. 195, 110313.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Establishment of a novel human fetal adrenal culture model that supports de novo and manipulated steroidogenesis

    Melau, C., Nielsen, J. E., Perlman, S., Lundvall, L., Thuesen, L. L., Hare, K. J., Hammerum, M. S., Frederiksen, H., Mitchell, R. T., Juul, A. & Jørgensen, A., 8 Mar 2021, In: The Journal of clinical endocrinology and metabolism. 106, 3, p. 843-857 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published
  11. Published

    Androgen Receptor Is Dispensable for X-Zone Regression in the Female Adrenal but Regulates Post-Partum Corticosterone Levels and Protects Cortex Integrity

    Gannon, A-L., O'Hara, L., Mason, I. J., Jørgensen, A., Frederiksen, H., Curley, M., Milne, L., Smith, S., Mitchell, R. T. & Smith, L. B., 21 Jan 2021, In: Frontiers in Endocrinology. 11, p. 599869 599869.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. 2020
  13. Published
  14. Published

    Maternal phthalate exposure associated with decreased testosterone/LH ratio in male offspring during mini-puberty. Odense Child Cohort

    Muerköster, A-P., Frederiksen, H., Juul, A., Andersson, A-M., Jensen, R. C., Glintborg, D., Kyhl, H. B., Andersen, M. S., Timmermann, C. A. G. & Jensen, T. K., Nov 2020, In: Environment International. 144, p. 106025 106025.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published
  16. Published

    Physiologically based kinetic (PBK) modelling and human biomonitoring data for mixture risk assessment

    Pletz, J., Blakeman, S., Paini, A., Parissis, N., Worth, A., Andersson, A-M., Frederiksen, H., Sakhi, A. K., Thomsen, C. & Bopp, S. K., Oct 2020, In: Environment International. 143, p. 105978

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Novel functions of the luteinizing hormone/chorionic gonadotropin receptor in prostate cancer cells and patients

    Stroomberg, H. V., Jørgensen, A., Brasso, K., Nielsen, J. E., Juul, A., Frederiksen, H., Blomberg Jensen, M. & Røder, M. A., 3 Sep 2020, In: PLoS One. 15, 9 September, p. e0238814 e0238814.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Influence of FGF23 and Klotho on male reproduction: Systemic vs direct effects

    Bøllehuus Hansen, L., Kaludjerovic, J., Nielsen, J. E., Rehfeld, A., Poulsen, N. N., Ide, N., Skakkebaek, N. E., Frederiksen, H., Juul, A., Lanske, B. & Blomberg Jensen, M., 1 Sep 2020, In: FASEB Journal. 34, 9, p. 12436-12449 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Grouping of endocrine disrupting chemicals for mixture risk assessment - Evidence from a rat study

    Christiansen, S., Axelstad, M., Scholze, M., Johansson, H. K. L., Hass, U., Mandrup, K., Frandsen, H. L., Frederiksen, H., Isling, L. K. & Boberg, J., Sep 2020, In: Environment International. 142, p. 105870 105870.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Male gonadal function after allogeneic hematopoietic stem cell transplantation in childhood: a cross-sectional, population-based study

    Mathiesen, S., Sørensen, K., Nielsen, M. M., Suominen, A., Ifversen, M., Grell, K., Lähteenmäki, P., Frederiksen, H., Juul, A., Müller, K. & Jahnukainen, K., Sep 2020, In: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 26, 9, p. 1635-1645 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Ablation of the canonical testosterone production pathway via knockout of the steroidogenic enzyme HSD17B3, reveals a novel mechanism of testicular testosterone production

    Rebourcet, D., Mackay, R., Darbey, A., Curley, M. K., Jørgensen, A., Frederiksen, H., Mitchell, R. T., O'Shaughnessy, P. J., Nef, S. & Smith, L. B., Aug 2020, In: FASEB Journal. 34, 8, p. 10373-10386 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Levels of endocrine-disrupting chemicals are associated with changes in the peri-pubertal epigenome

    Almstrup, K., Frederiksen, H., Andersson, A-M. & Juul, A., Aug 2020, In: Endocrine Connections. 9, 8, p. 845-857 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Predicting Transdermal Uptake of Phthalates and a Paraben from Cosmetic Cream Using the Measured Fugacity

    Eftekhari, A., Frederiksen, H., Andersson, A-M., Weschler, C. J. & Morrison, G., 16 Jun 2020, In: Environmental Science & Technology. 54, 12, p. 7471-7484 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Evaluation of Serum Insulin-like Factor 3 Quantification by LC-MS/MS as a Biomarker of Leydig Cell Function

    Albrethsen, J., Johannsen, T. H., Jørgensen, N., Frederiksen, H., Sennels, H. P., Jørgensen, H. L., Fahrenkrug, J., Petersen, J. H., Linneberg, A., Nordkap, L., Bang, A. K., Andersson, A-M. & Juul, A., 1 Jun 2020, In: The Journal of clinical endocrinology and metabolism. 105, 6, p. 1868-1877

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Use of stored serum in the study of time trends and geographical differences in exposure of pregnant women to phthalates

    Henriksen, L. S., Mathiesen, B. K., Assens, M., Krause, M., Skakkebæk, N. E., Juul, A., Andersson, A. M., Hart, R. J., Newnham, J. P., Keelan, J. A., Pennell, C., Main, K. M. & Frederiksen, H., 1 May 2020, In: Environmental Research. 184, p. 109231 109231.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Vitamin D and sex steroid production in men with normal or impaired Leydig cell function

    Holt, R., Mortensen, L. J., Harpelunde Poulsen, K., Nielsen, J. E., Frederiksen, H., Jørgensen, N., Jørgensen, A., Juul, A. & Blomberg Jensen, M., May 2020, In: The Journal of steroid biochemistry and molecular biology. 199, p. 105589 8 p., 105589.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Maternal serum concentrations of bisphenol A and propyl paraben in early pregnancy are associated with male infant genital development

    Fisher, B. G., Thankamony, A., Mendiola, J., Petry, C. J., Frederiksen, H., Andersson, A. M., Juul, A., Ong, K. K., Dunger, D. B., Hughes, I. A. & Acerini, C. L., 28 Apr 2020, In: Human reproduction (Oxford, England). 35, 4, p. 913-928 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    BPA and risk assessment

    Calafat, A. M., Koch, H. M., Andra, S. S., Antignac, J. P., Castaño, A., Choi, K., Covaci, A., Dekant, W., Doerge, D. R., Frederiksen, H., Göen, T., Kolossa-Gehring, M., Leblanc, A., Mueller, J. F., Nakayama, S. F., Nassif, J., St-Amand, A., Völkel, W., Wolff, M. S. & additional coauthors, 1 Apr 2020, In: The Lancet Diabetes and Endocrinology. 8, 4, p. 269-270 2 p.

    Research output: Contribution to journalLetterResearchpeer-review

  29. Published

    Maternal phthalate exposure and asthma, rhinitis and eczema in 552 children aged 5 years; A prospective cohort study

    Jøhnk, C., Høst, A., Husby, S., Schoeters, G., Timmermann, C. A. G., Kyhl, H. B., Beck, I. H., Andersson, A. M., Frederiksen, H. & Jensen, T. K., 13 Mar 2020, In: Environmental Health: A Global Access Science Source. 19, 1, p. 32 32.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Sex-specific estrogen levels and reference intervals from infancy to late adulthood determined by LC-MS/MS

    Frederiksen, H., Johannsen, T. H., Andersen, S. E., Albrethsen, J., Landersoe, S. K., Petersen, J. H., Andersen, A. N., Vestergaard, E. T., Schorring, M. E., Linneberg, A., Main, K. M., Andersson, A-M. & Juul, A., 1 Mar 2020, In: The Journal of clinical endocrinology and metabolism. 105, 3, p. 754-768

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Prenatal exposure to perfluorodecanoic acid is associated with lower circulating concentration of adrenal steroid metabolites during mini puberty in human female infants. The Odense Child Cohort

    Jensen, R. C., Glintborg, D., Gade Timmermann, C. A., Nielsen, F., Kyhl, H. B., Frederiksen, H., Andersson, A-M., Juul, A., Sidelmann, J. J., Andersen, H. R., Grandjean, P., Andersen, M. S. & Jensen, T. K., Mar 2020, In: Environmental Research. 182, p. 109101 109101.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published
  33. 2019
  34. Published

    Adipose tissue concentrations of non-persistent environmental phenols and local redox balance in adults from Southern Spain

    Artacho-Cordón, F., Ríos-Arrabal, S., León, J., Frederiksen, H., Sáenz, J. M., Martín-Olmedo, P., Fernández, M. F., Olea, N. & Arrebola, J. P., Dec 2019, In: Environment International. 133, Pt A, p. 105118 105118.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published
  36. Published

    Development and Interlaboratory Validation of Two Fast UPLC-MS-MS Methods Determining Urinary Bisphenols, Parabens and Phthalates

    van der Meer, T. P., van Faassen, M., Frederiksen, H., van Beek, A. P., Wolffenbuttel, B. H. R., Kema, I. P. & van Vliet-Ostaptchouk, J. V., 24 Jul 2019, In: Journal of Analytical Toxicology. 43, 6, p. 452-464 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Androgen receptor signalling in the male adrenal facilitates X-zone regression, cell turnover and protects against adrenal degeneration during ageing

    Gannon, A-L., O'Hara, L., Mason, J. I., Jørgensen, A., Frederiksen, H., Milne, L., Smith, S., Mitchell, R. T. & Smith, L. B., 18 Jul 2019, In: Scientific Reports. 9, 1, p. 10457 10457.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Characterization of Human Adrenal Steroidogenesis during Fetal Development

    Melau, C., Nielsen, J. E., Frederiksen, H., Kilcoyne, K., Perlman, S., Lundvall, L., Thuesen, L. L., Juul Hare, K., Andersson, A-M., Mitchell, R. T., Juul, A. & Jørgensen, A., 1 May 2019, In: The Journal of clinical endocrinology and metabolism. 104, 5, p. 1802-1812 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Ablation of glucocorticoid receptor in the hindbrain of the mouse provides a novel model to investigate stress disorders

    Gannon, A-L., O'Hara, L., Mason, J. I., Rebourcet, D., Smith, S., Traveres, A., Alcaide-Corral, C. J., Frederiksen, H., Jørgensen, A., Milne, L., Mitchell, R. T. & Smith, L. B., 1 Mar 2019, In: Scientific Reports. 9, 1, p. 3250 3250.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Prenatal bisphenol A exposure is associated with language development but not with ADHD-related behavior in toddlers from the Odense Child Cohort

    Jensen, T. K., Mustieles, V., Bleses, D., Frederiksen, H., Trecca, F., Schoeters, G., Andersen, H. R., Grandjean, P., Kyhl, H. B., Juul, A., Bilenberg, N. & Andersson, A-M., Mar 2019, In: Environmental Research. 170, p. 398-405 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Variations in repeated serum concentrations of UV filters, phthalates, phenols and parabens during pregnancy

    Assens, M., Frederiksen, H., Petersen, J. H., Larsen, T., Skakkebæk, N. E., Juul, A., Andersson, A-M. & Main, K. M., 1 Feb 2019, In: Environment International. 123, p. 318-324 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    A young testicular microenvironment protects Leydig cells against age-related dysfunction in a mouse model of premature aging

    Curley, M., Milne, L., Smith, S., Jørgensen, A., Frederiksen, H., Hadoke, P., Potter, P. & Smith, L. B., 2019, In: FASEB Journal. 33, 1, p. 978-995 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. 2018
  44. Published

    Nodal Signaling Regulates Germ Cell Development and Establishment of Seminiferous Cords in the Human Fetal Testis

    Jørgensen, A., Macdonald, J., Nielsen, J. E., Kilcoyne, K. R., Perlman, S., Lundvall, L., Langhoff Thuesen, L., Juul Hare, K., Frederiksen, H., Andersson, A-M., Skakkebæk, N. E., Juul, A., Sharpe, R. M., Rajpert-De Meyts, E. & Mitchell, R. T., 13 Nov 2018, In: Cell Reports. 25, 7, p. 1924-1937.e4

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Analyzing terephthalate metabolites in human urine as biomarkers of exposure: Importance of selection of metabolites and deconjugation enzyme

    Koch, H. M., Lessmann, F., Swan, S. H., Hauser, R., Kolossa-Gehring, M., Frederiksen, H., Andersson, A-M., Thomsen, C., Sakhi, A. K., Bornehag, C-G., Mueller, J. F., Rudel, R. A., Braun, J. M., Harth, V. & Brüning, T., 15 Oct 2018, In: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 1100-1101, p. 91-92 2 p.

    Research output: Contribution to journalLetterResearchpeer-review

  46. Published

    Environmental phenols and parabens in adipose tissue from hospitalized adults in Southern Spain

    Artacho-Cordón, F., Fernández, M. F., Frederiksen, H., Iribarne-Durán, L. M., Jiménez-Díaz, I., Vela-Soria, F., Andersson, A. M., Martin-Olmedo, P., Peinado, F. M., Olea, N. & Arrebola, J. P., Oct 2018, In: Environment International. 119, p. 203-211 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published
  48. Published

    Clinical proteomics: Insights from IGF-I

    Albrethsen, J., Frederiksen, H., Johannsen, T. H., Andersson, A-M. & Juul, A., Feb 2018, In: Clinica chimica acta; international journal of clinical chemistry. 477, p. 18-23 6 p.

    Research output: Contribution to journalReviewResearchpeer-review

  49. Published

    Bisphenol A, phthalate metabolites and glucose homeostasis in healthy normal-weight children

    Carlsson, A., Sørensen, K., Andersson, A-M., Frederiksen, H. & Juul, A., Jan 2018, In: Endocrine Connections. 7, 1, p. 232-238 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Presence of benzophenones commonly used as UV filters and absorbers in paired maternal and fetal samples

    Krause, M., Frederiksen, H., Sundberg, K., Jørgensen, F. S., Jensen, L. N., Nørgaard, P., Jørgensen, C., Ertberg, P., Juul, A., Drzewiecki, K. T., Skakkebaek, N. E. & Andersson, A. M., Jan 2018, In: Environmental International. 110, p. 51-60

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published
  52. Published

    Prenatal phthalate exposure and language development in toddlers from the Odense Child Cohort

    Olesen, T. S., Bleses, D., Andersen, H. R., Grandjean, P., Frederiksen, H., Trecca, F., Bilenberg, N., Kyhl, H. B., Dalsager, L., Jensen, I. K., Andersson, A-M. & Jensen, T. K., 2018, In: Neurotoxicology and Teratology. 65, p. 34-41 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Serum Phthalate and Triclosan Levels Have Opposing Associations With Risk Factors for Gestational Diabetes Mellitus

    Fisher, B. G., Frederiksen, H., Andersson, A-M., Juul, A., Thankamony, A., Ong, K. K., Dunger, D. B., Hughes, I. A. & Acerini, C. L., 2018, In: Frontiers in Endocrinology. 9, p. 99

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    The Possible Impact of Antenatal Exposure to Ubiquitous Phthalates Upon Male Reproductive Function at 20 Years of Age

    Hart, R. J., Frederiksen, H., Doherty, D. A., Keelan, J. A., Skakkebaek, N. E., Minaee, N. S., McLachlan, R., Newnham, J. P., Dickinson, J. E., Pennell, C. E., Norman, R. J. & Main, K. M., 2018, In: Frontiers in Endocrinology. 9, p. 288

    Research output: Contribution to journalJournal articleResearchpeer-review

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