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Rigshospitalet - a part of Copenhagen University Hospital
  1. 2019
  2. E-pub ahead of print

    Ruxolitinib treatment reduces monocytic superoxide radical formation without affecting hydrogen peroxide formation or systemic oxidative nucleoside damage in myelofibrosis

    Bjørn, M. E., Brimnes, M. K., Gudbrandsdottir, S., Andersen, C. L., Poulsen, H. E., Henriksen, T., Hasselbalch, H. C. & Nielsen, C. H., 20 Feb 2019, In : Leukemia and Lymphoma. p. 1-9 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Statin treatment, oxidative stress and inflammation in a Danish population

    Sørensen, A. L., Hasselbalch, H. C., Nielsen, C. H., Poulsen, H. E. & Ellervik, C., Feb 2019, In : Redox Biology. 21, p. 101088

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. E-pub ahead of print

    Prognostic role of genetic polymorphisms of the interleukin-6 signaling pathway in patients with severe heart failure

    Hansen, P. R., Nelveg-Kristensen, K. E., Rasmussen, H. B., Torp-Pedersen, C., Køber, L., Nielsen, C. H. & Enevold, C., 17 Jan 2019, In : The pharmacogenomics journal.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. 2018
  6. Published

    Safety and efficacy of combination therapy of interferon-α2 and ruxolitinib in polycythemia vera and myelofibrosis

    Mikkelsen, S. U., Kjaer, L., Bjørn, M. E., Knudsen, T. A., Sørensen, A. L., Andersen, C. B. L., Bjerrum, O. W., Brochmann, N., Fassi, D. E., Kruse, T. A., Larsen, T. S., Mourits-Andersen, H. T., Nielsen, C. H., Pallisgaard, N., Thomassen, M., Skov, V. & Hasselbalch, H. C., Aug 2018, In : Cancer Medicine. 7, 8, p. 3571-3581 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Reconstitution of Th17, Tc17 and Treg cells after paediatric haematopoietic stem cell transplantation: Impact of interleukin-7

    Kielsen, K., Ryder, L. P., Lennox-Hvenekilde, D., Gad, M., Nielsen, C. H., Heilmann, C., Ifversen, M., Pedersen, A. E. & Müller, K., Feb 2018, In : Immunobiology. 223, 2, p. 220-226 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Effects of rituximab and dexamethasone on regulatory and proinflammatory B-cell subsets in patients with primary immune thrombocytopenia

    Gudbrandsdottir, S., Brimnes, M., Køllgaard, T., Hasselbalch, H. C. & Nielsen, C. H., Jan 2018, In : European Journal of Haematology. 100, 1, p. 45-52 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Development of anti-drug antibodies is associated with shortened survival in patients with metastatic melanoma treated with ipilimumab

    Kverneland, A. H., Enevold, C., Donia, M., Bastholt, L., Svane, I. M. & Nielsen, C. H., 2018, In : OncoImmunology. 7, 5, p. e1424674

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published
  11. Published

    Relative efficiencies of peptidylarginine deiminase 2 and 4 in generating target sites for anti-citrullinated protein antibodies in fibrinogen, alpha-enolase and histone H3

    Damgaard, D., Bawadekar, M., Senolt, L., Stensballe, A., Shelef, M. A. & Nielsen, C. H., 2018, In : PLoS One. 13, 8, p. e0203214

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Surfactant Protein D Deficiency Aggravates Cigarette Smoke-Induced Lung Inflammation by Upregulation of Ceramide Synthesis

    Pilecki, B., Wulf-Johansson, H., Støttrup, C., Jørgensen, P. T., Djiadeu, P., Nexøe, A. B., Schlosser, A., Hansen, S. W. K., Madsen, J., Clark, H. W., Nielsen, C. H., Vestbo, J., Palaniyar, N., Holmskov, U. & Sorensen, G. L., 2018, In : Frontiers in Immunology. 9, p. 1-12 3013.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. 2017
  14. Published

    Reactive oxygen species inhibit catalytic activity of peptidylarginine deiminase

    Damgaard, D., Bjørn, M. E., Jensen, P. Ø. & Nielsen, C. H., Dec 2017, In : Journal of Enzyme Inhibition and Medicinal Chemistry. 32, 1, p. 1203-1208 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published
  16. Published

    Comorbidity of periodontal disease: two sides of the same coin? An introduction for the clinician

    Holmstrup, P., Damgaard, C., Olsen, I., Klinge, B., Flyvbjerg, A., Nielsen, C. H. & Hansen, P. R., 14 Jun 2017, In : Journal of Oral Microbiology. 9, 1, p. e1332710 1332710.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Peptidylarginine deiminase 2 is required for tumor necrosis factor alpha-induced citrullination and arthritis, but not neutrophil extracellular trap formation

    Bawadekar, M., Shim, D., Johnson, C. J., Warner, T. F., Rebernick, R., Damgaard, D., Nielsen, C. H., Pruijn, G. J. M., Nett, J. E. & Shelef, M. A., Jun 2017, In : Journal of Autoimmunity. 80, p. 39-47 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Calgizzarin (S100A11): a novel inflammatory mediator associated with disease activity of rheumatoid arthritis

    Andrés Cerezo, L., Šumová, B., Prajzlerová, K., Veigl, D., Damgaard, D., Nielsen, C. H., Pavelka, K., Vencovský, J. & Šenolt, L., 26 Apr 2017, In : Arthritis Research and Therapy. 19, 1, p. 79 88 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Cholesterol crystals enhance TLR2- and TLR4-mediated pro-inflammatory cytokine responses of monocytes to the proatherogenic oral bacterium Porphyromonas gingivalis

    Køllgaard, T., Enevold, C., Bendtzen, K., Hansen, P. R., Givskov, M., Holmstrup, P. & Nielsen, C. H., 24 Feb 2017, In : P L o S One. 12, 2, p. e0172773

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Long-term effects of angiotensin II blockade with irbesartan on inflammatory markers in hemodialysis patients: A randomized double blind placebo controlled trial (SAFIR study)

    Peters, C. D., Kjaergaard, K. D., Nielsen, C. H., Christensen, K. L., Bibby, B. M., Jensen, J. D. & Jespersen, B., Jan 2017, In : Hemodialysis international. International Symposium on Home Hemodialysis. 21, 1, p. 47-62 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Low pretreatment levels of myeloid-related protein-8/14 and C-reactive protein predict poor adherence to treatment with tumor necrosis factor inhibitors in juvenile idiopathic arthritis

    Alberdi-Saugstrup, M., Nielsen, S., Mathiessen, P., Nielsen, C. H. & Müller, K., Jan 2017, In : Clinical Rheumatology. 36, 1, p. 67-75 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Bioactive small molecules in commercially available cereal food: Benzoxazinoids

    Steffensen, S. K., Adhikari, K. B., Laursen, B. B., Jensen, C., Gregersen, P. L., Bhattarai, B., Marais, L. M., Schnoor, H. J., Jensen, B. M., Poulsen, L. K., Nielsen, C. H., Borre, M., Borre, M., Høyer, S. & Fomsgaard, I. S., 2017, In : Journal of Food Composition and Analysis. 64, p. 213-222 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Effect of thrombopoietin-receptor agonists on circulating cytokine and chemokine levels in patients with primary immune thrombocytopenia (ITP)

    Gudbrandsdottir, S., Ghanima, W., Nielsen, C. H., Feng, X., Hasselbalch, H. C. & Bussel, J., 2017, In : Platelets. 28, 5, p. 478-483 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Komorbiditet ved marginal parodontitis - to sider af samme sag?

    Holmstrup, P., Damgaard, C., Olsen, I., Klinge, B., Flyvbjerg, A., Nielsen, C. H. & Hansen, P. R., 2017, In : Tandlaegebladet. 121, 1, p. 52-59 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published
  26. Published

    Surface complement C3 fragments and cellular binding of microparticles in patients with SLE

    Winberg, L. K., Nielsen, C. H. & Jacobsen, S., 2017, In : Lupus science & medicine. 4, 1, p. e000193 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    The flame retardant DE-71 (a mixture of polybrominated diphenyl ethers) inhibits human differentiated thyroid cell function in vitro

    Kronborg, T. M., Hansen, J. F., Rasmussen, Å. K., Vorkamp, K., Nielsen, C. H., Frederiksen, M., Hofman-Bang, J., Hahn, C. H., Ramhøj, L. & Feldt-Rasmussen, U., 2017, In : P L o S One. 12, 6, p. e0179858

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. 2016
  29. Published

    Pseudomonas aeruginosa Microcolonies in Coronary Thrombi from Patients with ST-Segment Elevation Myocardial Infarction

    Hansen, G. M., Belstrøm, D., Nilsson, M., Helqvist, S., Nielsen, C. H., Holmstrup, P., Tolker-Nielsen, T., Givskov, M. & Hansen, P. R., 28 Dec 2016, In : P L o S One. 11, 12, p. e0168771

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published
  31. Published

    Lactobacillus reuteri supplements do not affect salivary IgA or cytokine levels in healthy subjects: A randomized, double-blind, placebo-controlled, cross-over trial

    Jørgensen, M. R., Keller, M. K., Kragelund, C., Hamberg, K., Ericson, D., Nielsen, C. H. & Twetman, S., Jul 2016, In : Acta Odontologica Scandinavica. 74, 5, p. 399-404 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Reduced glutathione as a physiological co-activator in the activation of peptidylarginine deiminase

    Damgaard, D., Bjørn, M. E., Steffensen, M. A., Pruijn, G. J. M. & Nielsen, C. H., 5 May 2016, In : Arthritis Research and Therapy. 18, 1, p. 102

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published
  34. Published

    Regulatory B and T cell responses in patients with autoimmune thyroid disease and healthy controls

    Kristensen, B. & Nielsen, C. H., Feb 2016, 27 p. (Danish Medical Bulletin (Online)).

    Research output: Book/ReportPh.D. thesisResearch

  35. Published

    Citrullinering – en posttranslationel proteinmodifikation af afgørende patogenetisk betydning i reumatoid artrit

    Nielsen, C. H. & Damgaard, D., 2016, In : BestPractice.

    Research output: Contribution to journalJournal articleCommunication

  36. Published

    Effects of the Commercial Flame Retardant Mixture DE-71 on Cytokine Production by Human Immune Cells

    Mynster Kronborg, T., Frohnert Hansen, J., Nielsen, C. H., Ramhøj, L., Frederiksen, M., Vorkamp, K. & Feldt-Rasmussen, U., 2016, In : P L o S One. 11, 4, p. e0154621

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Immunsystemet og den medicinske patient

    Nielsen, C. H., Helweg-Larsen, J., Feldt-Rasmussen, U. & Baslund, B., 2016, Medicin. Baslund, B., Feldt-Rasmussen, U., Kastrup, J. & Sørensen, P. S. (eds.). København: FADL's Forlag, p. 748-765 17 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterCommunication

  38. Published
  39. Published

    Non-Medical Switch from Originator to Biosimilar Infliximab in Patients with Inflammatory Arthritis – Impact on s-Infliximab and Antidrug-Antibodies. Results from the Danish Rheumatologic Biobank and the Danbio Registry

    Glintborg, B., Kringelbach, T. M., Høgdall, E., Sørensen, I. J., Jensen, D. V., Loft, A. G., Hendricks, O., Hansen, I. M. J., Linauskas, A., Kristensen, S., Lindegaard, H., Nordin, H., Bolstad, N., Warren, D., Warren, D., Gehin, J., Goll, G. L., Grøn, K. L., Eng, G. P., Enevold, C., Nielsen, C. H., Johansen, J. S. & Hetland, M. L., 2016, In : Arthritis & Rheumatology. 68, S10, 1997.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  40. Published
  41. 2015
  42. Published

    Telomerase Inhibitor Imetelstat in Essential Thrombocythemia and Myelofibrosis

    Bjørn, M. E., Nielsen, C. H. & Hasselbalch, H. C., 24 Dec 2015, In : The New England journal of medicine. 373, 26, p. 2579-80 2 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  43. Published

    Dietary exposure to benzoxazinoids enhances bacteria-induced monokine responses by peripheral blood mononuclear cells

    Damgaard, D., Jensen, B. M., Palarasah, Y., Friberg Bruun Nielsen, M., Adhikari, K. B., Schnoor, H. J., Juel-Berg, N., Poulsen, L. K., Fomsgaard, I. S. & Nielsen, C. H., Nov 2015, In : Molecular Nutrition & Food Research. 59, 11, p. 2190-8 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    The complement system and its role in the pathogenesis of periodontitis: current concepts

    Damgaard, C., Holmstrup, P., Van Dyke, T. E. & Nielsen, C. H., Jun 2015, In : Journal of Periodontal Research. 50, 3, p. 283-93 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Smoking is associated with increased levels of extracellular peptidylarginine deiminase 2 (PAD2) in the lungs

    Damgaard, D., Friberg Bruun Nielsen, M., Quisgaard Gaunsbaek, M., Palarasah, Y., Svane-Knudsen, V. & Nielsen, C. H., 22 Apr 2015, In : Clinical and Experimental Rheumatology. 33, 3, p. 405-8 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published
  47. Published

    Associations between gastrointestinal toxicity, micro RNA and cytokine production in patients undergoing myeloablative allogeneic stem cell transplantation

    Pontoppidan, P. L., Jordan, K., Carlsen, A. L., Uhlving, H. H., Kielsen, K., Christensen, M., Ifversen, M., Nielsen, C. H., Sangild, P., Heegaard, N. H. H., Heilmann, C., Sengeløv, H. & Müller, K., Mar 2015, In : International Immunopharmacology. 25, 1, p. 180-8 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Benzoxazinoids: Cereal phytochemicals with putative therapeutic and health-protecting properties

    Adhikari, K. B., Tanwir, F., Gregersen, P. L., Steffensen, S. K., Jensen, B. M., Poulsen, L. K., Nielsen, C. H., Høyer, S. B., Borre, M. & Fomsgaard, I. S., 19 Jan 2015, In : Molecular Nutrition & Food Research. 59, 7, p. 1324-38

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Absence of Bacteria on Coronary Angioplasty Balloons from Unselected Patients: Results with Use of a High Sensitivity Polymerase Chain Reaction Assay

    Hansen, G. M., Nilsson, M., Nielsen, C. H., Holmstrup, P., Helqvist, S., Tolker-Nielsen, T., Givskov, M. & Hansen, P. R., 2015, In : P L o S One. 10, 12, p. e0145657

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Altered balance between self-reactive Th17 cells and Th10 cells and between full-length FOXP3 and FOXP3 splice variants in Hashimoto's thyroiditis

    Kristensen, B., Hegedüs, L., Madsen, H. O., Smith, T. J. & Nielsen, C. H., 2015, In : Clinical and Experimental Immunology. 180, 1, p. 58-69

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Differentiation of salivary bacterial profiles of subjects with periodontitis and dental caries

    Belstrøm, D., Fiehn, N-E., Nielsen, C. H., Klepac-Ceraj, V., Paster, B. J., Twetman, S. & Holmstrup, P., 2015, In : Journal of Oral Microbiology. 7, 27429.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published
  53. Published

    Immune regulatory imprinting of monocyte derived dendritic cells by airway epithelial cells

    Papazian, D., Choden, T., Arge, M., Vorup-Jensen, T., Nielsen, C. H., Lund, K., Skjødt, K., Würtzen, P. A. & Hansen, S., 2015, In : American Journal of Respiratory Cell and Molecular Biology. p. 368-77

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. E-pub ahead of print

    Increased frequencies of interleukin-10 producing B cells expressing CD25 and TIM-1 in Hashimoto’s thyroiditis

    Kristensen, B., Hegedus, L., Lundy, SK., Brimnes, M. K., Smith, T. J. & Nielsen, C. H., 2015, In : P L o S One. e0127949.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    Influence of phthalates on in vitro innate and adaptive immune responses

    Hansen, J. F., Nielsen, C. H., Brorson, M. M., Frederiksen, H., Hartoft-Nielsen, M-L., Rasmussen, Å. K., Bendtzen, K. & Feldt-Rasmussen, U., 2015, In : P L o S One. 10, 6, p. e0131168

    Research output: Contribution to journalJournal articleResearchpeer-review

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