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Rigshospitalet - a part of Copenhagen University Hospital
  1. 2021
  2. Published
  3. 2020
  4. Published

    Tumor cell MT1-MMP is dispensable for osteosarcoma tumor growth, bone degradation and lung metastasis

    Ingvarsen, S. Z., Gårdsvoll, H., van Putten, S., Nørregaard, K. S., Krigslund, O., Meilstrup, J. A., Tran, C., Jürgensen, H. J., Melander, M. C., Nielsen, C. H., Kjaer, A., Bugge, T. H., Engelholm, L. H. & Behrendt, N., 5 Nov 2020, In: Scientific Reports. 10, 1, p. 19138 19138.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Monitoring CD8a+ T Cell Responses to Radiotherapy and CTLA-4 Blockade Using [64Cu]NOTA-CD8a PET Imaging

    Kristensen, L. K., Christensen, C., Alfsen, M. Z., Cold, S., Nielsen, C. H. & Kjaer, A., Aug 2020, In: Molecular Imaging and Biology. 22, 4, p. 1021-1030 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Quantitative PET imaging of PD-L1 expression in xenograft and syngeneic tumour models using a site-specifically labelled PD-L1 antibody

    Christensen, C., Kristensen, L. K., Alfsen, M. Z., Nielsen, C. H. & Kjaer, A., May 2020, In: European Journal of Nuclear Medicine and Molecular Imaging. 47, 5, p. 1302-1313 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. 2019
  8. Published

    Proteomics-Based Comparative Mapping of the Secretomes of Human Brown and White Adipocytes Reveals EPDR1 as a Novel Batokine

    Deshmukh, A. S., Peijs, L., Beaudry, J. L., Jespersen, N. Z., Nielsen, C. H., Ma, T., Brunner, A. D., Larsen, T. J., Bayarri-Olmos, R., Prabhakar, B. S., Helgstrand, C., Severinsen, M. C. K., Holst, B., Kjaer, A., Tang-Christensen, M., Sanfridson, A., Garred, P., Privé, G. G., Pedersen, B. K., Gerhart-Hines, Z., Nielsen, S., Drucker, D. J., Mann, M. & Scheele, C., 5 Nov 2019, In: Cell Metabolism. 30, 5, p. 963-975.e7

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Affinity-Guided Conjugation to Antibodies for Use in Positron Emission Tomography

    Skovsgaard, M. B., Jeppesen, T. E., Mortensen, M. R., Nielsen, C. H., Madsen, J., Kjaer, A. & Gothelf, K. V., 20 Mar 2019, In: Bioconjugate Chemistry. 30, 3, p. 881-887 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Oxime Coupling of Active Site Inhibited Factor Seven with a Nonvolatile, Water-Soluble Fluorine-18 Labeled Aldehyde

    Jeppesen, T. E., Kristensen, L. K., Nielsen, C. H., Petersen, L. C., Kristensen, J. B., Behrens, C., Madsen, J. & Kjaer, A., 20 Mar 2019, In: Bioconjugate Chemistry. 30, 3, p. 775-784

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    CD4+ and CD8a+ PET imaging predicts response to novel PD-1 checkpoint inhibitor: studies of Sym021 in syngeneic mouse cancer models

    Kristensen, L. K., Fröhlich, C., Christensen, C., Melander, M. C., Poulsen, T. T., Galler, G. R., Lantto, J., Horak, I. D., Kragh, M., Nielsen, C. H. & Kjaer, A., 2019, In: Theranostics. 9, 26, p. 8221-8238 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Site-specifically labeled 89Zr-DFO-trastuzumab improves immuno-reactivity and tumor uptake for immuno-PET in a subcutaneous HER2-positive xenograft mouse model

    Kristensen, L. K., Christensen, C., Jensen, M. M., Agnew, B. J., Schjöth-Frydendahl, C., Kjaer, A. & Nielsen, C. H., 2019, In: Theranostics. 9, 15, p. 4409-4420 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. 2018
  14. Published

    Drug concentrations and anti-drug antibodies during treatment with biosimilar infliximab (CT-P13) in routine care

    Glintborg, B., Kringelbach, T., Bolstad, N., Warren, D. J., Eng, G., Sørensen, I. J., Loft, A. G., Hendricks, O., Hansen, I., Linauskas, A., Nordin, H., Kristensen, S., Lindegaard, H., Jensen, D. V., Goll, G. L., Høgdall, E., Gehin, J., Enevold, C., Nielsen, C. H., Krogh, N. S., Johansen, J. S. & Hetland, M. L., Sep 2018, In: Scandinavian Journal of Rheumatology. 47, 5, p. 418-421 4 p.

    Research output: Contribution to journalLetterResearchpeer-review

  15. Published

    Cardiolipin Synthesis in Brown and Beige Fat Mitochondria Is Essential for Systemic Energy Homeostasis

    Sustarsic, E. G., Ma, T., Lynes, M. D., Larsen, M., Karavaeva, I., Havelund, J. F., Nielsen, C. H., Jedrychowski, M. P., Moreno-Torres, M., Lundh, M., Plucinska, K., Jespersen, N. Z., Grevengoed, T. J., Kramar, B., Peics, J., Hansen, J. B., Shamsi, F., Forss, I., Neess, D., Keipert, S., Wang, J., Stohlmann, K., Brandslund, I., Christensen, C., Jørgensen, M. E., Linneberg, A., Pedersen, O., Kiebish, M. A., Qvortrup, K., Han, X., Pedersen, B. K., Jastroch, M., Mandrup, S., Kjær, A., Gygi, S. P., Hansen, T., Gillum, M. P., Grarup, N., Emanuelli, B., Nielsen, S., Scheele, C., Tseng, Y-H., Færgeman, N. J. & Gerhart-Hines, Z., 3 Jul 2018, In: Cell Metabolism. 28, 1, p. 159-174 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Site-SpecificCu Labeling of the Serine Protease, Active Site Inhibited Factor Seven Azide (FVIIai-N), Using Copper Free Click Chemistry

    Jeppesen, T. E., Kristensen, L. K., Nielsen, C. H., Petersen, L. C., Kristensen, J. B., Behrens, C., Madsen, J. & Kjaer, A., 17 Jan 2018, In: Bioconjugate Chemistry. 29, 1, p. 117-125 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    The Apolipoprotein M/S1P Axis Controls Triglyceride Metabolism and Brown Fat Activity

    Christoffersen, C., Federspiel, C. K., Borup, A., Christensen, P. M., Madsen, A. N., Heine, M., Nielsen, C. H., Kjaer, A., Holst, B., Heeren, J. & Nielsen, L. B., 2 Jan 2018, In: Cell Reports. 22, 1, p. 175-188 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    A blood biomarker for monitoring response to anti-EGFR therapy

    Hughes, N. P., Xu, L., Nielsen, C. H., Chang, E., Hori, S. S., Natarajan, A., Lee, S., Kjær, A., Kani, K., Wang, S. X., Mallick, P. & Gambhir, S. S., 2018, In: Cancer biomarkers : section A of Disease markers. 22, 2, p. 333-344 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Effect of inhibition of CBP-coactivated β-catenin-mediated Wnt signalling in uremic rats with vascular calcifications

    Gravesen, E., Nordholm, A., Mace, M., Morevati, M., Høgdall, E., Nielsen, C., Kjær, A., Olgaard, K. & Lewin, E., 2018, In: PLoS One. 13, 8, p. e0201936

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. 2017
  21. Published

    Uremia does not affect neointima formation in mice

    Aarup, A., Nielsen, C. H., Bisgaard, L. S., Bot, I., El-Ali, H. H., Kjaer, A., Nielsen, L. B. & Pedersen, T. X., 26 Jul 2017, In: Scientific Reports. 7, 1, p. 6496

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published
  23. Published
  24. Published
  25. Published

    Neodymium-140 DOTA-LM3: Evaluation of anGenerator for PET with a Non-Internalizing Vector

    Severin, G. W., Kristensen, L. K., Nielsen, C. H., Fonslet, J., Jensen, A. I., Frellsen, A. F., Jensen, K. M., Elema, D. R., Maecke, H., Kjær, A., Johnston, K. & Köster, U., 2017, In: Frontiers in Medicine. 4, p. e98

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. 2016
  27. Published

    PET Imaging of Tissue Factor in Pancreatic Cancer Using 64Cu-Labeled Active Site-Inhibited Factor VII

    Nielsen, C. H., Jeppesen, T. E., Kristensen, L. K., Jensen, M. M., El Ali, H. H., Madsen, J., Wiinberg, B., Petersen, L. C. & Kjaer, A., Jul 2016, In: Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 57, 7, p. 1112-9 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Influence of complement on neutrophil extracellular trap release induced by bacteria

    Palmer, L. J., Damgaard, C., Holmstrup, P. & Nielsen, C. H., Feb 2016, In: Journal of Periodontal Research. 51, 1, p. 70-6 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Quantitative PET Imaging of Tissue Factor Expression Using 18F-Labeled Active Site-Inhibited Factor VII

    Nielsen, C. H., Erlandsson, M., Jeppesen, T. E., Jensen, M. M., Kristensen, L. K., Madsen, J., Petersen, L. C. & Kjaer, A., Jan 2016, In: Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 57, 1, p. 89-95 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. 2015
  31. Published

    In vivo imaging of therapy response to a novel pan-HER antibody mixture using FDG and FLT positron emission tomography

    Nielsen, C. H., Jensen, M. M., Kristensen, L., Dahlman, A., Fröhlich, C., Jacobsen, H. J., Poulsen, T. T., Lantto, J., Horak, I. D., Kragh, M. & Kjaer, A., 10 Nov 2015, In: Oncotarget. 6, 35, p. 37486-99 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Bringing Radiotracing to Titanium-Based Antineoplastics: Solid Phase Radiosynthesis, PET and ex Vivo Evaluation of Antitumor Agent [(45)Ti](salan)Ti(dipic)

    Severin, G., Nielsen, C. H., Jensen, A. I., Fonslet, J., Kjær, A. & Zhuravlev, F., 24 Sep 2015, In: Journal of Medicinal Chemistry. 58, 18, p. 7591-5 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    [(64) Cu]-labelled trastuzumab: optimisation of labelling by DOTA and NODAGA conjugation and initial evaluation in mice

    Schjoeth-Eskesen, C., Nielsen, C. H., Heissel, S., Højrup, P., Hansen, P. R., Gillings, N. & Kjaer, A., 30 May 2015, In: Journal of Labelled Compounds and Radiopharmaceuticals. 58, 6, p. 227-33 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Synthesis and characterization of (18)F-labeled active site inhibited factor VII (ASIS)

    Erlandsson, M., Nielsen, C. H., Jeppesen, T. E., Kristensen, J., Petersen, L. C., Madsen, J. & Kjaer, A., 15 May 2015, In: Journal of Labelled Compounds and Radiopharmaceuticals. 58, 5, p. 196-201 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published
  36. Published
  37. Published

    The use of dynamic nuclear polarization (13)C-pyruvate MRS in cancer

    Gutte Borgwardt, H., Hansen, A. E., Johannesen, H. H., Clemmensen, A. E., Ardenkjær-Larsen, J. H., Nielsen, C. H. & Kjær, A., 2015, In: American Journal of Nuclear Medicine and Molecular Imaging. 5, 5, p. 548-60 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. 2013
  39. Published

    MicroRNA-regulated non-viral vectors with improved tumor specificity in an orthotopic rat model of hepatocellular carcinoma

    Ronald, J. A., Katzenberg, R., Nielsen, C. H., Jae, H. J., Hofmann, L. V. & Gambhir, S. S., Oct 2013, In: Gene Therapy. 20, 10, p. 1006-13 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Commentary: antibodies reacting with the infliximab Fab portion--something new? Authors' reply

    Nielsen, C. H., Steenholdt, C., Palarasah, Y., Bendtzen, K., Teisner, A., Brynskov, J. & Teisner, B., Sep 2013, In: Alimentary Pharmacology and Therapeutics. 38, 5, p. 552-3 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Pre-existing IgG antibodies cross-reacting with the Fab region of infliximab predict efficacy and safety of infliximab therapy in inflammatory bowel disease

    Steenholdt, C., Palarasah, Y., Bendtzen, K., Teisner, A., Brynskov, J., Teisner, B. & Nielsen, C. H., Jun 2013, In: Alimentary Pharmacology and Therapeutics. 37, 12, p. 1172-83 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Molecular photoacoustic imaging of follicular thyroid carcinoma

    Levi, J., Kothapalli, S-R., Bohndiek, S., Yoon, J-K., Dragulescu-Andrasi, A., Nielsen, C., Tisma, A., Bodapati, S., Gowrishankar, G., Yan, X., Chan, C., Starcevic, D. & Gambhir, S. S., 15 Mar 2013, In: Clinical Cancer Research. 19, 6, p. 1494-502 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. 2012
  44. Published

    New positron emission tomography (PET) radioligand for imaging σ-1 receptors in living subjects

    James, M. L., Shen, B., Zavaleta, C. L., Nielsen, C. H., Mesangeau, C., Vuppala, P. K., Chan, C., Avery, B. A., Fishback, J. A., Matsumoto, R. R., Gambhir, S. S., McCurdy, C. R. & Chin, F. T., 2012, In: Journal of Medicinal Chemistry. 55, 19, p. 8272-82 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. 2010
  46. Published

    PET imaging of tumor neovascularization in a transgenic mouse model with a novel 64Cu-DOTA-knottin peptide

    Nielsen, C. H., Kimura, R. H., Withofs, N., Tran, P. T., Miao, Z., Cochran, J. R., Cheng, Z., Felsher, D., Kjær, A., Willmann, J. K. & Gambhir, S. S., 15 Nov 2010, In: Cancer Research. 70, 22, p. 9022-30 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Efficacy of Rituximab in Combination with Dexamethasone Vs Dexamethasone in Newly Diagnosed Patients with Primary Immune Thrombocytopenia - An Interim Analysis of A Prospective Randomised Study

    Gudbrandsdottir, S., Frederiksen, H., Rasmussen, I. H., Jensen, B., Kjeldsen, L., Klausen, T. W., Larsen, H., Mounts-Andersen, H. T., Nielsen, C. H., Nielsen, O. J., Plesner, T. L., Pulczynski, S., Roennow-Jessen, D., Garm, C. H. & Birgens, H., 2010, In: Haematologica. 95, p. 253 1 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

ID: 32159997