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Rigshospitalet - a part of Copenhagen University Hospital

Birgitte Rahbek Kornum

(Former)

  1. 2018
  2. Published

    Type 1 narcolepsy is not present in 29 HPV-vaccinated individuals with subjective sleep complaints

    Torstensen, E. W., Brinth, L. S., Mehlsen, J., Kornum, B. R. & Jennum, P. J., Nov 2018, In : Danish Medical Journal. 65, 11, p. A6511

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    DNMT1 regulates expression of MHC class i in post-mitotic neurons

    Gustafsson, J. R., Katsioudi, G., Degn, M., Ejlerskov, P., Issazadeh-Navikas, S. & Kornum, B. R., 3 Jul 2018, In : Molecular Brain. 11, 1, p. 36

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Flow cytometry analysis of T-cell subsets in cerebrospinal fluid of narcolepsy type 1 patients with long-lasting disease

    Moresco, M., Lecciso, M., Ocadlikova, D., Filardi, M., Melzi, S., Kornum, B. R., Antelmi, E., Pizza, F., Mignot, E., Curti, A. & Plazzi, G., 1 Apr 2018, In : Sleep Medicine. 44, p. 53-60 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    N-terminal tagging of human P2X7 receptor disturbs calcium influx and dye uptake

    Dreisig, K., Kristensen, N. P., Dommer, M. W., Jørgensen, N. R. & Kornum, B. R., 1 Mar 2018, In : Purinergic Signalling. 14, 1, p. 83-90 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Increased interferon-mediated immunity following in vitro and in vivo Modafinil treatment on peripheral immune cells

    Zager, A., Brandão, W. N., Margatho, R. O., Cruz, D. S. G., Peron, J. P., Tufik, S., Andersen, M. L., Moresco, M., Pizza, F., Plazzi, G., Kornum, B. R. & Palermo-Neto, J., 2 Feb 2018, In : Progress in Neuro-Psychopharmacology and Biological Psychiatry. 81, p. 297-305 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    The wake-promoting drug Modafinil prevents motor impairment in sickness behavior induced by LPS in mice: Role for dopaminergic D1 receptor

    Zager, A., Brandão, W. N., Margatho, R. O., Peron, J. P., Tufik, S., Andersen, M. L., Kornum, B. R. & Palermo-Neto, J., 2 Feb 2018, In : Progress in neuro-psychopharmacology & biological psychiatry. 81, p. 468-476 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Human P2Y11 expression level affects human P2X7 receptor-mediated cell death

    Dreisig, K., Sund, L., Dommer, M. W., Kristensen, N. P., Boddum, K., Viste, R., Fredholm, S., Odum, N., Jäättelä, M., Skov, S. & Kornum, B. R., 2018, In : Frontiers in Immunology. 9, p. 1159

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. 2017
  10. Published
  11. Published

    Rare missense mutations in P2RY11 in narcolepsy with cataplexy

    Degn, M., Dauvilliers, Y., Dreisig, K., Lopez, R., Pfister, C., Pradervand, S., Rahbek Kornum, B. & Tafti, M., 1 Jun 2017, In : Brain : a journal of neurology. 140, 6, p. 1657-1668 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Sleep spindle density in narcolepsy

    Christensen, J. A. E., Nikolic, M., Hvidtfelt, M., Kornum, B. R. & Jennum, P., Jun 2017, In : Sleep Medicine. 34, p. 40-49 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Sleep-wake stability in narcolepsy patients with normal, low and unmeasurable hypocretin levels

    Hansen, M. H., Kornum, B. R. & Jennum, P., Jun 2017, In : Sleep Medicine. 34, p. 1-6 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Novel method for evaluation of eye movements in patients with narcolepsy

    Christensen, J. A. E., Kempfner, L., Leonthin, H. L., Hvidtfelt, M., Nikolic, M., Kornum, B. R. & Jennum, P., May 2017, In : Sleep Medicine. 33, p. 171-180

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Narcolepsy

    Kornum, B. R., Knudsen, S., Ollila, H. M., Pizza, F., Jennum, P. J., Dauvilliers, Y. & Overeem, S., 9 Feb 2017, In : Nature reviews. Disease primers. 3, p. 16100

    Research output: Contribution to journalReviewResearchpeer-review

  16. Published

    Cerebrospinal fluid biomarkers of neurodegeneration are decreased or normal in narcolepsy

    Jennum, P. J., Pedersen, L. Ø., Bahl, J. M. C., Stausbøll, S. M., Fog, K., Holm, A., Kornum, B. R. & Gammeltoft, S., Jan 2017, In : Sleep. 40, 1, p. zsw006

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Genetics of Human Sleep and Sleep Disorders

    Kornum, B. R., 2017, Handbook of Neurobehavioral Genetics and Phenotyping. Tucci, V. (ed.). 1 ed. John/Wiley & Sons, Inc, p. 295-322

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  18. Published
  19. 2016
  20. Published

    Neurobasal media facilitates increased specificity of siRNA-mediated knockdown in primary cerebellar cultures

    Gustafsson, J. R., Katsioudi, G., Issazadeh-Navikas, S. & Kornum, B. R., 1 Dec 2016, In : Journal of Neuroscience Methods. 274, p. 116-124 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Validation of antibodies for neuroanatomical localization of the P2Y11 receptor in macaque brain

    Dreisig, K., Degn, M., Sund, L., Hadaczek, P., Samaranch, L., San Sebastian, W., Bankiewicz, K. & Rahbek Kornum, B., Dec 2016, In : Journal of Chemical Neuroanatomy. 78, p. 25-33 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    A critical look at the function of the P2Y11 receptor

    Dreisig, K. & Kornum, B. R., Sep 2016, In : Purinergic Signalling. 12, 3, p. 427-37 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Monozygotic twins discordant for narcolepsy type 1 and multiple sclerosis

    Jennum, P. J., Kornum, B. R., Issa, N. M., Gammeltoft, S., Tommerup, N., Morling, N., Tümer, Z. & Knudsen, S., Aug 2016, In : Neurology® neuroimmunology & neuroinflammation. 3, 4, p. e249

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    The European Narcolepsy Network (EU-NN) database

    Khatami, R., Luca, G., Baumann, C. R., Bassetti, C. L., Bruni, O., Canellas, F., Dauvilliers, Y., Del Rio-Villegas, R., Feketeova, E., Ferri, R., Geisler, P., Högl, B., Jennum, P., Kornum, B. R., Lecendreux, M., Martins-da-Silva, A., Mathis, J., Mayer, G., Paiva, T., Partinen, M., Peraita-Adrados, R., Plazzi, G., Santamaria, J., Sonka, K., Riha, R., Tafti, M., Wierzbicka, A., Young, P., Lammers, G. J., Overeem, S. & European Narcolepsy Network, Jun 2016, In : Journal of Sleep Research. 25, 3, p. 356-64 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Cerebrospinal Fluid Hypocretin-1 (Orexin-A) Level Fluctuates with Season and Correlates with Day Length

    Boddum, K., Hansen, M. H., Jennum, P. J. & Kornum, B. R., 2016, In : P L o S One. 11, 3, p. e0151288

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. 2015
  27. Published

    An optimized method for measuring hypocretin-1 peptide in the mouse brain reveals differential circadian regulation of hypocretin-1 levels rostral and caudal to the hypothalamus

    Justinussen, J., Holm, A. & Kornum, B. R., 3 Dec 2015, In : Neuroscience. 310, p. 354-61 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Type 1 narcolepsy: a CD8(+) T cell-mediated disease?

    Degn, M. & Kornum, B. R., Sep 2015, In : New York Academy of Sciences. Annals. 1351, p. 80-8 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Serum cytokine levels in Kleine-Levin syndrome

    Kornum, B. R., Rico, T., Lin, L., Huang, Y-S., Arnulf, I., Jennum, P. & Mignot, E., Aug 2015, In : Sleep Medicine. 16, 8, p. 961-5 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Cerebrospinal fluid cytokine levels in type 1 narcolepsy patients very close to onset

    Kornum, B. R., Pizza, F., Knudsen, S., Plazzi, G., Jennum, P. & Mignot, E., 11 Mar 2015, In : Brain, Behavior, and Immunity. 49, p. 54-8

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    EIF3G is associated with narcolepsy across ethnicities

    Holm, A., Lin, L., Faraco, J., Mostafavi, S., Battle, A., Zhu, X., Levinson, D. F., Han, F., Gammeltoft, S., Jennum, P., Mignot, E. & Kornum, B. R., 11 Feb 2015, In : European journal of human genetics : EJHG. 23, 11, p. 1573-80

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    HLA-DPB1 and HLA class I confer risk of and protection from narcolepsy

    Ollila, H. M., Ravel, J-M., Han, F., Faraco, J., Lin, L., Zheng, X., Plazzi, G., Dauvilliers, Y., Pizza, F., Hong, S-C., Jennum, P., Knudsen, S., Kornum, B. R., Dong, X. S., Yan, H., Hong, H., Coquillard, C., Mahlios, J., Jolanki, O., Einen, M., Arnulf, I., Lavault, S., Högl, B., Frauscher, B., Crowe, C., Partinen, M., Huang, Y. S., Bourgin, P., Vaarala, O., Désautels, A., Montplaisir, J., Mack, S. J., Mindrinos, M., Fernandez-Vina, M. & Mignot, E., 8 Jan 2015, In : American Journal of Human Genetics. 96, 1, p. 136-46 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. 2014
  34. Published

    MiRNA profiles in cerebrospinal fluid from patients with central hypersomnias

    Holm, A., Bang-Berthelsen, C. H., Knudsen, S., Modvig, S., Kornum, B. R., Gammeltoft, S. & Jennum, P. J., 15 Dec 2014, In : Journal of the Neurological Sciences. 347, 1-2, p. 199-204 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Does autoreactivity have a role in narcolepsy?

    Partinen, M., Kornum, B. R., Plazzi, G., Jennum, P., Julkunen, I. & Vaarala, O., Nov 2014, In : Lancet neurology. 13, 11, p. 1072-3 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    miRNA profiles in plasma from patients with sleep disorders reveal dysregulation of miRNAs in narcolepsy and other central hypersomnias

    Holm, A., Bang-Berthelsen, C. H., Knudsen, S., Kornum, B. R., Nielsen, S. M., Jennum, P. & Gammeltoft, S., Sep 2014, In : Sleep. 37, 9, p. 1525-33 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Narcolepsy as an autoimmune disease: the role of H1N1 infection and vaccination

    Partinen, M., Kornum, B. R., Plazzi, G., Jennum, P., Julkunen, I. & Vaarala, O., Jun 2014, In : Lancet neurology. 13, 6, p. 600-13 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. 2013
  39. Published

    Association mellem narkolepsi og H1N1-influenza

    Kornum, B. R., Knudsen, S., Gammeltoft, S. & Jennum, P., 18 Mar 2013, In : Ugeskrift for Laeger. 175, 12, p. 815

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    5-HT radioligands for human brain imaging with PET and SPECT

    Paterson, L. M., Kornum, B. R., Nutt, D. J., Pike, V. W. & Knudsen, G. M., 2013, In : Medicinal Research Reviews. 33, 1, p. 54-111 58 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Hjernens regulering af søvn

    Gammeltoft, S., Holm, A. & Kornum, B. R., 2013, Søvn. 1. ed. Munksgård Danmark, p. 39-49 11 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterCommunication

  42. Published

    ImmunoChip study implicates antigen presentation to T cells in narcolepsy

    Faraco, J., Lin, L., Kornum, B. R., Kenny, E. E., Trynka, G., Einen, M., Rico, T. J., Lichtner, P., Dauvilliers, Y., Arnulf, I., Lecendreux, M., Javidi, S., Geisler, P., Mayer, G., Pizza, F., Poli, F., Plazzi, G., Overeem, S., Lammers, G. J., Kemlink, D., Sonka, K., Nevsimalova, S., Rouleau, G., Desautels, A., Montplaisir, J., Frauscher, B., Ehrmann, L., Högl, B., Jennum, P., Bourgin, P., Peraita-Adrados, R., Iranzo, A., Bassetti, C., Chen, W-M., Concannon, P., Thompson, S. D., Damotte, V., Fontaine, B., Breban, M., Gieger, C., Klopp, N., Deloukas, P., Wijmenga, C., Hallmayer, J., Onengut-Gumuscu, S., Rich, S. S., Winkelmann, J. & Mignot, E., 2013, In : P L o S Genetics (Online). 9, 2, p. e1003270

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. 2012
  44. Published

    Early IVIg treatment has no effect on post-H1N1 narcolepsy phenotype or hypocretin deficiency

    Knudsen, S., Biering-Sørensen, B., Kornum, B. R., Petersen, E., Ibsen, J. D., Gammeltoft, S., Mignot, E. & Jennum, P. J., 2012, In : Neurology. 79, 1, p. 102-3 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Predictors of hypocretin (orexin) deficiency in narcolepsy without cataplexy

    Andlauer, O., Moore, H., Hong, S-C., Dauvilliers, Y., Kanbayashi, T., Nishino, S., Han, F., Silber, M. H., Rico, T., Einen, M., Kornum, B. R., Jennum, P., Knudsen, S., Nevsimalova, S., Poli, F., Plazzi, G. & Mignot, E., 2012, In : Sleep. 35, 9, p. 1247-55F

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. 2011
  47. Published

    An approach for serotonin depletion in pigs: effects on serotonin receptor binding

    Ettrup, A., Kornum, B. R., Weikop, P. & Knudsen, G. M., 2011, In : Synapse (New York). 65, 2, p. 136-45 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Cognitive testing of pigs (Sus scrofa) in translational biobehavioral research

    Kornum, B. R. & Knudsen, G. M., 2011, In : Neuroscience and Biobehavioral Reviews. 35, 3, p. 437-51 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Common variants in P2RY11 are associated with narcolepsy

    Kornum, B. R., Kawashima, M., Faraco, J., Lin, L., Rico, T. J., Hesselson, S., Axtell, R. C., Kuipers, H., Weiner, K., Hamacher, A., Kassack, M. U., Han, F., Knudsen, S., Li, J., Dong, X., Winkelmann, J., Plazzi, G., Nevsimalova, S., Hong, S-C., Honda, Y., Honda, M., Högl, B., Ton, T. G. N., Montplaisir, J., Bourgin, P., Kemlink, D., Huang, Y-S., Warby, S., Einen, M., Eshragh, J. L., Miyagawa, T., Desautels, A., Ruppert, E., Hesla, P. E., Poli, F., Pizza, F., Frauscher, B., Jeong, J-H., Lee, S-P., Strohl, K. P., Longstreth, W. T., Kvale, M., Dobrovolna, M., Ohayon, M. M., Nepom, G. T., Wichmann, H-E., Rouleau, G. A., Gieger, C., Levinson, D. F., Gejman, P. V., Meitinger, T., Peppard, P., Young, T., Jennum, P., Steinman, L., Tokunaga, K., Kwok, P-Y., Risch, N., Hallmayer, J. & Mignot, E., 2011, In : Nature Genetics. 43, 1, p. 66-71 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published
  51. 2010
  52. Published

    Radiosynthesis and evaluation of 11C-CIMBI-5 as a 5-HT2A receptor agonist radioligand for PET

    Ettrup, A., Palner, M., Gillings, N., Santini, M. A., Hansen, M., Kornum, B. R., Rasmussen, L. K., Någren, K. Å., Madsen, J., Begtrup, M. & Knudsen, G. M., 1 Nov 2010, In : Journal of Nuclear Medicine. 51, 11, p. 1763-70 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Adeno-associated viral vector serotypes 1 and 5 targeted to the neonatal rat and pig striatum induce widespread transgene expression in the forebrain

    Kornum, B. R., Stott, S. R. W., Mattsson, B., Wisman, L., Ettrup, A., Hermening, S., Knudsen, G. M. & Kirik, D., 1 Mar 2010, In : Experimental Neurology. 222, 1, p. 70-85 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. 2009
  55. Published

    Species differences in blood-brain barrier transport of three positron emission tomography radioligands with emphasis on P-glycoprotein transport

    Syvänen, S., Lindhe, O., Palner, M., Kornum, B. R., Rahman, O., Långström, B., Knudsen, G. M. & Hammarlund-Udenaes, M., Mar 2009, In : Drug Metabolism and Disposition. 37, 3, p. 635-43 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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