Forskning
Udskriv Udskriv
Switch language
Rigshospitalet - en del af Københavns Universitetshospital
Udgivet

Trends in Costs of Thyroid Disease Treatment in Denmark during 1995-2015

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

DOI

  1. 2018 European Thyroid Association (ETA) Guidelines on the Diagnosis and Management of Central Hypothyroidism

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Treating Hypothyroidism with Thyroxine/Triiodothyronine Combination Therapy in Denmark: Following Guidelines or Following Trends?

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Anxiety and depression are more prevalent in patients with graves' disease than in patients with nodular goitre

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Dysregulation of a long noncoding RNA reduces leptin leading to a leptin-responsive form of obesity

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Sex-Specific Epidemiology of Heart Failure Risk and Mortality in Europe: Results From the BiomarCaRE Consortium

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  4. Association of alcohol consumption with allergic disease and asthma: a multi-centre Mendelian randomization analysis

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  5. The association of celiac disease and allergic disease in a general adult population

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  • Line Tang Møllehave
  • Allan Linneberg
  • Tea Skaaby
  • Nils Knudsen
  • Lars Ehlers
  • Torben Jørgensen
  • Betina Heinsbæk Thuesen
Vis graf over relationer

Background: Iodine fortification (IF) may contribute to changes in costs of thyroid disease treatment through changes in disease patterns. From a health economic perspective, assessment of the development in costs of thyroid disease treatment in the population is pertinent.

Objectives: To assess the trends in annual medicine and hospital costs of thyroid disease treatment during 1995-2015 in Denmark, i.e., before and after the introduction of mandatory IF in 2000.

Methods: Information on treatments for thyroid disease (antithyroid medication, thyroid hormone therapy, thyroid surgery, and radioiodine treatment) was obtained from nationwide registers. Costs were valued at 2015 prices using sales prices for medicines and the Danish Diagnosis-Related Group (DRG) and Danish Ambulatory Grouping System (DAGS) tariffs of surgeries/radioiodine treatments. Results were adjusted for changes in population size and age and sex distribution.

Results: The total direct medicine and hospital costs of thyroid disease treatment increased from EUR ∼190,000 per 100,000 persons in 1995 to EUR ∼270,000 per 100,000 persons in 2015. This was mainly due to linearly increased costs of thyroid hormone therapy and increased costs of thyroid surgery since 2008. Costs of antithyroid medication increased slightly and transiently after IF, while costs of radioiodine treatment remained constant. Costs of thyroid hormone therapy and thyroid surgery did not follow the development in the prevalence of hypothyroidism and structural thyroid diseases observed in concurrent studies.

Conclusion: The costs of total direct medicine and hospital costs for thyroid disease treatment in Denmark increased from 1995 to 2015. This is possibly due to several factors, e.g., changes in treatment practices, and the direct effect of IF alone remains to be estimated.

OriginalsprogEngelsk
TidsskriftEuropean Thyroid Journal
Vol/bind7
Udgave nummer2
Sider (fra-til)75-83
Antal sider9
ISSN2235-0640
DOI
StatusUdgivet - mar. 2018

ID: 53659091