Forskning
Udskriv Udskriv
Switch language
Rigshospitalet - en del af Københavns Universitetshospital
E-pub ahead of print

Time Trial Performance Is Sensitive to Low-Volume Autologous Blood Transfusion

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. Heavy-Load Lifting: Acute Response in Breast Cancer Survivors at Risk for Lymphedema

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. No Superior Adaptations to Carbohydrate Periodization in Elite Endurance Athletes

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Intermittent Standing but not a Moderate Exercise Bout Reduces Postprandial Glycemia

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  4. Delayed Effect of Blood Flow-restricted Resistance Training on Rapid Force Capacity

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  5. Measuring Children's Physical Activity: Compliance Using Skin-Taped Accelerometers

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. Platelet increment is not associated with endothelial damage in haematological patients: a prospective observational study

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Use of red blood cells in Danish intensive care units: A population-based register study

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Storage time of red blood cells among ICU patients with septic shock

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Vis graf over relationer

PURPOSE: This study tested the hypothesis that autologous blood transfusion (ABT) of ~50% of the red blood cells (RBCs) from a standard 450 ml phlebotomy would increase mean power in a cycling time trial. Additionally, the study investigated whether further ABT of RBCs obtained from another 450 ml phlebotomy would increase repeated cycling sprint ability.

METHODS: In a randomized, double-blind, placebo-controlled crossover design (3-month wash-out), nine highly trained male subjects donated two 450 ml blood bags each (BT-trial) or were sham phlebotomized (PLA-trial). Four weeks later, a 650 kcal time trial (n=7) was performed three days before and 2 h after receiving either ~50% (135 ml) of the RBCs or a sham transfusion. On the following day, transfusion of RBCs (235 ml) from the second donation or sham transfusion was completed. A 4×30 s all-out cycling sprint interspersed by 4 min of recovery was performed six days before and three days after the second ABT (n=9).

RESULTS: The mean power was increased in time trials from before to after transfusion (P<0.05) in BT (213±35 vs. 223±38 W; mean±SD) but not in PLA (223±42 vs. 224±46 W). In contrast, the mean power output across the four 30 s sprint bouts remained similar in BT (639±35 vs. 644±26 W) and PLA (638±43 vs. 639±25 W).

CONCLUSION: ABT of only ~135 ml of RBCs is sufficient to increase mean power in a 650 kcal cycling time trial by ~5% in highly trained men. In contrast, a combined high-volume transfusion of ~135 and ~235 ml of RBCs does not alter 4×30 s all-out cycling performance interspersed with 4 min of recovery.

OriginalsprogEngelsk
TidsskriftMedicine and Science in Sports and Exercise
ISSN0195-9131
DOI
StatusE-pub ahead of print - 2019

ID: 56578635