Forskning
Udskriv Udskriv
Switch language
Rigshospitalet - en del af Københavns Universitetshospital
Udgivet

The economic and personal burden of cluster headache: a controlled cross-sectional study

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

DOI

  1. Provoked versus spontaneous migraine attacks: pathophysiological similarities and differences

    Publikation: Bidrag til tidsskriftReviewForskningpeer review

  2. One-quarter of individuals with weekly headache have never consulted a medical doctor: a Danish nationwide cross-sectional survey

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Imaging the inflammatory phenotype in migraine

    Publikation: Bidrag til tidsskriftReviewForskningpeer review

  1. Reply to 'Paracetamol use in pregnancy - neglecting context promotes misinterpretation'

    Publikation: Bidrag til tidsskriftLetterForskningpeer review

  2. Intracranial pressure and optic disc changes in a rat model of obstructive hydrocephalus

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Vis graf over relationer

Background: Cluster headache is a less-prevalent primary headache disorder but is overrepresented with regards to use of health care and social services. More insight into the socioeconomic impact is required. Methods: We investigated both the personal and societal disease burden and cost in 400 patients with well-classified cluster headache according to the ICHD-criteria and 200 sex- and age matched controls. All participants completed a cross sectional questionnaire and semi-structured interview. Results: Patients with chronic cluster headache constituted 146 out of 400 (37%). Overall, restriction in personal and/or professional life was reported by 94% of patients during attack periods. Even in remission, nine times as many episodic patients rated their health as poor/very poor compared to controls (9% vs 1%, p = 0.002). For chronic patients, the odds of rating health as good/very good were ten times lower compared to controls (OR:10.10, 95%CI:5.29–18.79. p < 0.001) and three times lower compared to episodic patients in remission (OR:3.22, 95%CI:1.90–5.47, p < 0.001). Additionally, chronic cluster headache patients were 5 times more likely to receive disability pension compared to episodic (OR:5.0, 95%CI:2.3–10.9, p < 0.001). The mean direct annual costs amounted to 9,158€ and 2,763€ for chronic and episodic patients, respectively (p < 0.001). We identified a substantial loss of productivity due to absence from work resulting in a higher indirect cost of 11,809 €/year/patient in the chronic population and 3,558 €/year/patient in the episodic population. Presenteeism could not be quantified but productivity was reduced in patients by 65% in periods with attacks compared to controls. Conclusion: Cluster headache has a major negative impact on personal life, self-perceived health, and societal cost. Patients with the chronic variant are vastly more burdened. Patients with the episodic form were still markedly affected during the remission period. This study highlights the need for more effective therapy to lighten the burden on patients and society.

OriginalsprogEngelsk
Artikelnummer58
TidsskriftJournal of Headache and Pain
Vol/bind23
Udgave nummer1
Sider (fra-til)1-11
Antal sider11
ISSN1129-2377
DOI
StatusUdgivet - 24 maj 2022

Bibliografisk note

© 2022. The Author(s).

ID: 78348412