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Rigshospitalet - en del af Københavns Universitetshospital
Udgivet

Surgical Management of Undescended Testis - Timetable and Outcome: A Debate

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DOI

  1. Parental Acceptance Rate of Testicular Tissue Cryopreservation in Danish Boys with Cryptorchidism

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Human RTEL1 associates with Poldip3 to facilitate responses to replication stress and R-loop resolution

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Sertoli Cell Number Correlates with Serum Inhibin B in Infant Cryptorchid Boys

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  4. ERG promotes the maintenance of hematopoietic stem cells by restricting their differentiation

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  5. Loss of TET2 in hematopoietic cells leads to DNA hypermethylation of active enhancers and induction of leukemogenesis

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. Intestinal perfusion assessed by quantitative fluorescence angiography in piglets with necrotizing enterocolitis

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Characterization and Survival of Human Infant Testicular Cells After Direct Xenotransplantation

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Fertility preservation in boys facing gonadotoxic cancer therapy

    Publikation: Bidrag til tidsskriftReviewForskningpeer review

  4. Serial Inhibin B Measurements in Boys with Congenital Monorchism Indicate Compensatory Testicular Hypertrophy in Early Infancy

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Vis graf over relationer

Around 1.4-3.8% of boys in the Western world are operated because of cryptorchidism. This means that orchidopexy remains one of the most common surgical procedures performed in boys. As a consequence, several consensus reports, guidelines, and reviews dealing with the management of cryptorchidism have been published recently. Based on our research and 30 years' experience with the management of cryptorchidism, the intention of the present publication is to advise on the surgical management and comment on the expected outcome, especially with focus on the controversies related to guidelines and reviews. Except for late referral and waiting lists, which may be practical problems, there is no reason to postpone orchidopexy for nonsyndromic congenital cryptorchid testes beyond 6 months. There is good evidence that such strategy improves the fertility potential and decreases the risk of testicular cancer. In cases with genuine gonadotropin insufficiency, early surgical correction is not enough and adjuvant LH-RH treatment should be implemented to improve the fertility potential. Cryopreservation may be an option in case of treatment failure of adjuvant LH-RH. A prerequisite for such management includes serum hormone assessment and evaluation of testicular biopsies at orchidopexy. Ascended testes contribute to 20-60% of operative cases and should be treated when diagnosed.

OriginalsprogEngelsk
TidsskriftGenes and Development
Vol/bind13
Udgave nummer1
Sider (fra-til)11-19
Antal sider9
ISSN0890-9369
DOI
StatusUdgivet - 2019

Bibliografisk note

© 2019 S. Karger AG, Basel.

ID: 56874145