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Simvastatin effects on skeletal muscle: relation to decreased mitochondrial function and glucose intolerance

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Author

Larsen, Steen ; Stride, Nis Ottesen ; Hey-Mogensen, Martin ; Hansen, Christina ; Bang, Lia E ; Bundgaard, Henning ; Nielsen, Lars B ; Helge, Jørn Wulff ; Dela, Flemming. / Simvastatin effects on skeletal muscle : relation to decreased mitochondrial function and glucose intolerance. I: Journal of the American College of Cardiology. 2013 ; Bind 61, Nr. 1. s. 44-53.

Bibtex

@article{68b7c12a20a341a7b76be33abc11c66a,
title = "Simvastatin effects on skeletal muscle: relation to decreased mitochondrial function and glucose intolerance",
abstract = "Glucose tolerance and skeletal muscle coenzyme Q(10) (Q(10)) content, mitochondrial density, and mitochondrial oxidative phosphorylation (OXPHOS) capacity were measured in simvastatin-treated patients (n = 10) and in well-matched control subjects (n = 9).",
keywords = "Blood Glucose, Case-Control Studies, Cell Respiration, Electron Transport, Electron Transport Complex I, Electron Transport Complex II, Glucose Intolerance, Glucose Tolerance Test, Humans, Hydroxymethylglutaryl-CoA Reductase Inhibitors, Insulin Resistance, Male, Middle Aged, Mitochondria, Muscle, Muscle Fibers, Skeletal, Muscle, Skeletal, Oxidative Phosphorylation, Simvastatin, Ubiquinone",
author = "Steen Larsen and Stride, {Nis Ottesen} and Martin Hey-Mogensen and Christina Hansen and Bang, {Lia E} and Henning Bundgaard and Nielsen, {Lars B} and Helge, {J{\o}rn Wulff} and Flemming Dela",
note = "Copyright {\textcopyright} 2013 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.",
year = "2013",
month = jan,
day = "8",
doi = "10.1016/j.jacc.2012.09.036",
language = "English",
volume = "61",
pages = "44--53",
journal = "American College of Cardiology. Journal",
issn = "0735-1097",
publisher = "Elsevier Inc",
number = "1",

}

RIS

TY - JOUR

T1 - Simvastatin effects on skeletal muscle

T2 - relation to decreased mitochondrial function and glucose intolerance

AU - Larsen, Steen

AU - Stride, Nis Ottesen

AU - Hey-Mogensen, Martin

AU - Hansen, Christina

AU - Bang, Lia E

AU - Bundgaard, Henning

AU - Nielsen, Lars B

AU - Helge, Jørn Wulff

AU - Dela, Flemming

N1 - Copyright © 2013 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.

PY - 2013/1/8

Y1 - 2013/1/8

N2 - Glucose tolerance and skeletal muscle coenzyme Q(10) (Q(10)) content, mitochondrial density, and mitochondrial oxidative phosphorylation (OXPHOS) capacity were measured in simvastatin-treated patients (n = 10) and in well-matched control subjects (n = 9).

AB - Glucose tolerance and skeletal muscle coenzyme Q(10) (Q(10)) content, mitochondrial density, and mitochondrial oxidative phosphorylation (OXPHOS) capacity were measured in simvastatin-treated patients (n = 10) and in well-matched control subjects (n = 9).

KW - Blood Glucose

KW - Case-Control Studies

KW - Cell Respiration

KW - Electron Transport

KW - Electron Transport Complex I

KW - Electron Transport Complex II

KW - Glucose Intolerance

KW - Glucose Tolerance Test

KW - Humans

KW - Hydroxymethylglutaryl-CoA Reductase Inhibitors

KW - Insulin Resistance

KW - Male

KW - Middle Aged

KW - Mitochondria, Muscle

KW - Muscle Fibers, Skeletal

KW - Muscle, Skeletal

KW - Oxidative Phosphorylation

KW - Simvastatin

KW - Ubiquinone

U2 - 10.1016/j.jacc.2012.09.036

DO - 10.1016/j.jacc.2012.09.036

M3 - Journal article

C2 - 23287371

VL - 61

SP - 44

EP - 53

JO - American College of Cardiology. Journal

JF - American College of Cardiology. Journal

SN - 0735-1097

IS - 1

ER -

ID: 42693874