Forskning
Udskriv Udskriv
Switch language
Rigshospitalet - en del af Københavns Universitetshospital
Udgivet

Sibling history is associated with heart failure after a first myocardial infarction

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

DOI

  1. Coronary risk stratification of patients with newly diagnosed heart failure

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Associations between common ECG abnormalities and out-of-hospital cardiac arrest

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Prevalence of early stages of heart failure in an elderly risk population: the Copenhagen Heart Failure Risk Study

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  4. Early follow-up after open heart valve surgery reduces healthcare costs: a propensity matched study

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  5. Echocardiographic subtypes of heart failure in consecutive hospitalised patients with dyspnoea

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. Age-specific trends in incidence and survival of out-of-hospital cardiac arrest from presumed cardiac cause in Denmark 2002-2014

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Valve regurgitation in patients surviving endocarditis and the subsequent risk of heart failure

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Sudden death in heart failure: do we understand what we observe?

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  4. 123I-MIBG for detection of subacute doxorubicin-induced cardiotoxicity in patients with malignant lymphoma

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Vis graf over relationer

Objective: Morbidity and mortality due to heart failure (HF) as a complication of myocardial infarction (MI) is high, and remains among the leading causes of death and hospitalisation. This study investigated the association between family history of MI with or without HF, and the risk of developing HF after first MI.

Methods: Through nationwide registries, we identified all individuals aged 18-50 years hospitalised with first MI from 1997 to 2016 in Denmark. We identified 13 810 patients with MI, and the cohort was followed until HF diagnosis, second MI, 3 years after index MI, emigration, death or the end of 2016, whichever occurred first. HRs were estimated by Cox hazard regression models adjusted for sex, age, calendar year and comorbidities (reference: patients with no family history of MI).

Results: After adjustment, we observed an increased risk of MI-induced HF for those having a sibling with MI with HF (HR 2.05, 95% CI 1.02 to 4.12). Those having a sibling with MI without HF also had a significant, but lower increased risk of HF (HR 1.39, 95% CI 1.05 to 1.84). Parental history of MI with or without HF was not associated with HF.

Conclusion: In this nationwide cohort, sibling history of MI with or without HF was associated with increased risk of HF after first MI, while a parental family history was not, suggesting that shared environmental factors may predominate in the determination of risk for developing HF.

OriginalsprogEngelsk
TidsskriftOpen Heart
Vol/bind7
Udgave nummer1
Sider (fra-til)e001143
ISSN2053-3624
DOI
StatusUdgivet - 2020

Bibliografisk note

© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

ID: 59734831