Forskning
Udskriv Udskriv
Switch language
Rigshospitalet - en del af Københavns Universitetshospital
Udgivet

Short-Term Flow Changes in Monochorionic Survivor Twins after Ultrasound-Guided Umbilical Cord Occlusion

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

DOI

  1. Intrathecal IgM as a Prognostic Marker in Multiple Sclerosis

    Publikation: Bidrag til tidsskriftReviewForskningpeer review

  2. Cell-Free Fetal DNA in the Early and Late First Trimester

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Magnetic Resonance Imaging: A New Tool to Optimize the Prediction of Fetal Anemia?

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. Prenatal detection rate of major congenital heart defects in Copenhagen from 2015 to 2018

    Publikation: Bidrag til tidsskriftLetterForskningpeer review

  2. Long-term consequences of prenatal progesterone exposure

    Publikation: Bidrag til tidsskriftKommentar/debatForskningpeer review

  3. National data on the early clinical use of non-invasive prenatal testing in public and private healthcare in Denmark 2013-2017

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Vis graf over relationer

OBJECTIVE: To determine hemodynamic changes by Doppler ultrasound of the living fetus during 24 h after umbilical cord occlusion (UCO) in monochorionic diamniotic (MCDA) twin pregnancies.

METHOD: We conducted a prospective observational study on fetuses undergoing UCO from 2015 to 2017. Doppler parameters peak systolic velocity (PSV) and umbilical pulsatility index (PI) were obtained in the middle cerebral artery (MCA), umbilical artery (UA) and ductus venosus (DV) before and right after UCO, and at 1, 3, 6, 12, and 24 h after. We used multiple of the median (MoM) to adjust for gestational age. Spaghetti plots visualized flow changes over time. Mixed model adjusting for paired longitudinal data compared the values at different time points.

RESULTS: A total of 16 women were included. MCA-PSV dropped within the first hour after surgery from 0.91 to 0.82 MoM (p = 0.08). MCA-PI and UA-PI increased in the first hour from 0.75 to 0.91 MoM (p = 0.02) and 0.94 to 0.98 MoM (p = 0.22), respectively. The DV-PIV increased to 1.14 MoM 3 h after surgery (p = 0.07). The spaghetti plots illustrated the small changes within the first hours and showed a stabilization of flow measurements near initial values 24 h after UCO.

CONCLUSION: Within the first hours after UCO the circulation of the survivor twin undergoes small hemodynamic changes.

OriginalsprogEngelsk
TidsskriftFetal Diagnosis and Therapy
Vol/bind47
Udgave nummer1
Sider (fra-til)45-53
Antal sider9
ISSN1015-3837
DOI
StatusUdgivet - 1 jan. 2020

Bibliografisk note

© 2019 S. Karger AG, Basel.

ID: 58966727