Forskning
Udskriv Udskriv
Switch language
Rigshospitalet - en del af Københavns Universitetshospital
Udgivet

Real-time changes in brain tissue oxygen during endovascular treatment of cerebral vasospasm

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. Evaluation of Intracranial Pressure in Different Body Postures and Disease Entities

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Influence of brain natriuretic peptide on phenotypic change of cerebral vasculature

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. Acute endovascular reperfusion treatment in patients with ischaemic stroke and large-vessel occlusion (Denmark 2011–2017)

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Early Postoperative 18F-FET PET/MRI for Pediatric Brain and Spinal Cord Tumors

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Response to Cognitive outcome following glioma surgery

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  4. Endovaskulær terapi ved iskæmisk apopleksi

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Vis graf over relationer

The use of endovascular intervention to treat cerebral vasospasm after subarachnoid hemorrhage has increased. Although the effect on angiographic vasospasm can be easily demonstrated, the effect on cerebral blood flow and clinical outcome is still controversial. In this report, we investigate minute-by-minute changes in brain tissue oxygen during balloon angioplasty and intraarterial administration of vasodilators in three patients.Our results confirm that endovascular intervention is capable of not only resolving angiographic vasospasm, but also of normalizing values of brain tissue oxygen pressure (PtiO₂) in target parenchyma. However, during the intervention, dangerously low levels of brain tissue oxygen, leading to cerebral infarction, may occur. Thus, no clinical improvement was seen in two of the patients and a dramatic worsening was observed in the third patient. Because the decrease in brain tissue oxygen was seen after administration of vasopressor agents, this may be a contributing factor.

OriginalsprogEngelsk
BogserieActa Neurochirurgica. Supplementum
Vol/bind120
Sider (fra-til)183-6
Antal sider4
ISSN0065-1419
DOI
StatusUdgivet - 2015

ID: 45752138