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Rigshospitalet - en del af Københavns Universitetshospital
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Preclinical safety assessment of the 5-HT2A receptor agonist PET radioligand [ 11C]Cimbi-36

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DOI

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  2. Combined PET/MRI: Multi-modality Multi-parametric Imaging Is Here

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  3. Microvessel Density But Not Neoangiogenesis Is Associated with (18)F-FDG Uptake in Human Atherosclerotic Carotid Plaques

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  4. Increased cellular proliferation in rat skeletal muscle and tendon in response to exercise: use of FLT and PET/CT

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  1. Effect of blood glucose and body weight on image quality in brain [18F]FDG PET imaging

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Blocking of efflux transporters in rats improves translational validation of brain radioligands

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Oral contraceptives and the serotonin 4 receptor: a molecular brain imaging study in healthy women

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Vis graf over relationer
[11C]Cimbi-36 was recently developed as an agonist radioligand for brain imaging of serotonin 2A receptors (5-HT2A) with positron emission tomography (PET). This may be used to quantify the high-affinity state of 5-HT2A receptors and may have the potential to quantify changes in cerebral 5-HT levels in vivo. We here investigated safety aspects related to clinical use of [11C]Cimbi-36, including radiation dosimetry and in vivo pharmacology.
OriginalsprogEngelsk
TidsskriftMolecular Imaging and Biology
Vol/bind15
Udgave nummer4
Sider (fra-til)376-83
Antal sider8
ISSN1536-1632
DOI
StatusUdgivet - aug. 2013

ID: 42576417