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Rigshospitalet - en del af Københavns Universitetshospital
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Pharmacokinetic and pharmacodynamic variability as possible causes for different drug responses in migraine. A comment

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Vis graf over relationer

The pharmacokinetics of antimigraine drugs zolmitriptan and sumatriptan varied considerably with a fourfold to 10-fold variation in plasma levels. In addition, the pharmacodynamics of triptans as investigated in vitro also varied considerably. In theory, there should probably be a 10-fold variation in doses available, but in clinical practice a fourfold difference in doses will probably cover the needs of most patients.

OriginalsprogEngelsk
TidsskriftCephalalgia : an international journal of headache
Vol/bind27
Udgave nummer10
Sider (fra-til)1091-3
Antal sider3
ISSN0333-1024
DOI
StatusUdgivet - okt. 2007

ID: 44846792