Forskning
Udskriv Udskriv
Switch language
Rigshospitalet - en del af Københavns Universitetshospital
Udgivet

Patient-Specific Computer Simulation in TAVR With the Self-Expanding Evolut R Valve

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

DOI

  1. Patient-Specific Implantation Technique to Obtain Neo-Commissural Alignment With Self-Expanding Transcatheter Aortic Valves

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Technical Considerations for Transcatheter Aortic Valve Replacement With the Navitor Transcatheter Heart Valve

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Transcatheter Treatment of Residual Significant Mitral Regurgitation Following TAVR: A Multicenter Registry

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  4. Redo-TAVR: What About the Coronary Arteries?

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. Patient-Specific Implantation Technique to Obtain Neo-Commissural Alignment With Self-Expanding Transcatheter Aortic Valves

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Technical Considerations for Transcatheter Aortic Valve Replacement With the Navitor Transcatheter Heart Valve

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. First-in-human results of the OMEGA™ Left Atrial Appendage Occluder for Patients with Non-Valvular Atrial Fibrillation

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  4. Impact of early hospital discharge on clinical outcomes after transcatheter aortic valve implantation

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  • Nahid El Faquir
  • Ole De Backer
  • Johan Bosmans
  • Tanja Rudolph
  • Nicola Buzzatti
  • Gintautas Bieliauskas
  • Valerie Collas
  • Hendrik Wienemann
  • Davide Schiavi
  • Paul Cummins
  • Zouhair Rahhab
  • Herbert Kroon
  • Quinten Wolff
  • Mattie Lenzen
  • Joana Maria Ribeiro
  • Azeem Latib
  • Matti Adam
  • Lars Søndergaard
  • Ben Ren
  • Nicolas Van Mieghem
  • Peter de Jaegere
Vis graf over relationer

OBJECTIVES: The aim of this study was to assess the added value and predictive power of the TAVIguide (Added Value of Patient-Specific Computer Simulation in Transcatheter Aortic Valve Implantation) software in clinical practice.

BACKGROUND: Optimal outcome after transcatheter aortic valve replacement (TAVR) may become more important as TAVR shifts toward low-risk patients. Patient-specific computer simulation is able to provide prediction of outcome after TAVR. Its clinical role and validation of accuracy, however, have not yet been studied prospectively.

METHODS: A prospective, observational, multicenter study was conducted among 80 patients with severe aortic stenosis treated with the Evolut R valve. Simulation was performed in 42 patients and no simulation in 38. A comparison between the valve size (decision 1) and target depth of implantation selected by the operator on the basis of multislice computed tomography and the valve size (decision 2) and target depth of implantation selected after simulation were the primary endpoints. Predictive power was examined by comparing the simulated and observed degree of aortic regurgitation.

RESULTS: Decision 2 differed from decision 1 in 1 of 42 patients because of predicted paravalvular leakage, and changes in valve type occurred in 2 of 42. In 39 of 42 patients, decisions 1 and 2 were similar. Target depth of implantation differed in 7 of 42 patients after simulation (lower in 4 and higher in 3). In 16 of 42 patients, simulation affected the TAVR procedure; in 9, the operator avoided additional measures to achieve the target depth of implantation, and in 7 patients, additional measures were performed. There was a trend toward a higher degree of predicted than observed aortic regurgitation (17.5 vs. 12 ml/s; p = 0.13).

CONCLUSIONS: Patient-specific computer simulation did not affect valve size selection but did affect the selection of the target depth of implantation and the execution of TAVR to achieve the desired target depth of implantation.

OriginalsprogEngelsk
TidsskriftJACC: Cardiovascular Interventions
Vol/bind13
Udgave nummer15
Sider (fra-til)1803-1812
Antal sider10
ISSN1936-8798
DOI
StatusUdgivet - 10 aug. 2020

Bibliografisk note

Copyright © 2020 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.

ID: 62107887