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Rigshospitalet - en del af Københavns Universitetshospital
Udgivet

Neutralizing antibodies hamper IFNbeta bioactivity and treatment effect on MRI in patients with MS

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  1. Enterovirus Meningitis in Adults: A Prospective Nationwide Population-Based Cohort Study

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  2. Accuracy of a Deep Learning System for Classification of Papilledema Severity on Ocular Fundus Photographs

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  3. Autoimmune Encephalitis Related to Cancer Treatment With Immune Checkpoint Inhibitors: A Systematic Review

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  1. Ocrelizumab treatment in multiple sclerosis: A Danish population-based cohort study

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  2. Biomarkers of Cerebral Injury for Prediction of Postoperative Cognitive Dysfunction in Patients Undergoing Cardiac Surgery

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Vis graf over relationer
We measured neutralizing antibodies (NABs) and the in vivo biologic response to interferon-beta on neopterin and beta(2)-microglobulin blood levels. All NAB-negative patients had an in vivo biologic response (full or partial), whereas all high-level positive patients had no response. High-level NAB patients had more MRI activity than NAB-negative patients (p = 0.031). Patients with a full response had less MRI activity than patients without biologic response (p = 0.032).
OriginalsprogEngelsk
TidsskriftNeurology
Vol/bind67
Udgave nummer9
Sider (fra-til)1681-83
DOI
StatusUdgivet - 2006

ID: 32257035