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Infectious diseases detected by screening after arrival to Denmark in internationally adopted children

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@article{bbb6c7ebe0bb469cba625cb803e5915e,
title = "Infectious diseases detected by screening after arrival to Denmark in internationally adopted children",
abstract = "AIM: To show the prevalence of selected infectious diseases among internationally adopted children (IAC) in Denmark.BACKGROUND: Each year approximately 200 IAC arrive in Denmark. These are at increased risk of infectious diseases rarely seen in Danish children. Studies from the 1990s showed that 60% of IAC had infectious diseases and that the majority of these were undetected without screening.METHODS: The study is a prospective study of medical records from children seen in the adoption clinic at Copenhagen University Hospital in the period 2009-2013. Screening was done for hepatitis A (HAV), B (HBV) and C (HCV), syphilis, HIV, tuberculosis (TB) and intestinal parasites.RESULTS: In 245 IAC tested, 2% had evidence of recent HAV infection, 3% with HBV and one child with HCV, and no cases of HIV were found. One child had antibodies against syphilis (anti-Trpa AB positivity), and 2% were latently infected with tuberculosis. We found 30% infected with pathogenic intestinal parasites. Only 46% had serologic evidence of immunisation against HBV.CONCLUSION: The prevalence of infections in IAC was lower than previously reported but compared to the general population, a higher prevalence of intestinal parasites, hepatitis and tuberculosis was found. We recommend that IAC are offered screening shortly after arrival.",
keywords = "adoptees, hepatitis A, hepatitis B, infectious diseases, intestinal parasites, tuberculosis",
author = "Nielsen, {Agnethe Vale} and Jesper Kjaergaard and Pedersen, {Tine Marie} and Helmuth, {Ida Glode} and Ulrikka Nygaard and Nielsen, {Helle Winter} and Christensen, {Vibeke Brix} and Kurtzhals, {J{\o}rgen Anders Lindholm} and Anja Poulsen",
note = "{\textcopyright} 2019 Foundation Acta Paediatrica. Published by John Wiley & Sons Ltd.",
year = "2020",
month = may,
doi = "10.1111/apa.15045",
language = "English",
volume = "109",
pages = "1004--1010",
journal = "Acta paediatrica",
issn = "1651-2227",
publisher = "Wiley-Blackwell Publishing Ltd",
number = "5",

}

RIS

TY - JOUR

T1 - Infectious diseases detected by screening after arrival to Denmark in internationally adopted children

AU - Nielsen, Agnethe Vale

AU - Kjaergaard, Jesper

AU - Pedersen, Tine Marie

AU - Helmuth, Ida Glode

AU - Nygaard, Ulrikka

AU - Nielsen, Helle Winter

AU - Christensen, Vibeke Brix

AU - Kurtzhals, Jørgen Anders Lindholm

AU - Poulsen, Anja

N1 - © 2019 Foundation Acta Paediatrica. Published by John Wiley & Sons Ltd.

PY - 2020/5

Y1 - 2020/5

N2 - AIM: To show the prevalence of selected infectious diseases among internationally adopted children (IAC) in Denmark.BACKGROUND: Each year approximately 200 IAC arrive in Denmark. These are at increased risk of infectious diseases rarely seen in Danish children. Studies from the 1990s showed that 60% of IAC had infectious diseases and that the majority of these were undetected without screening.METHODS: The study is a prospective study of medical records from children seen in the adoption clinic at Copenhagen University Hospital in the period 2009-2013. Screening was done for hepatitis A (HAV), B (HBV) and C (HCV), syphilis, HIV, tuberculosis (TB) and intestinal parasites.RESULTS: In 245 IAC tested, 2% had evidence of recent HAV infection, 3% with HBV and one child with HCV, and no cases of HIV were found. One child had antibodies against syphilis (anti-Trpa AB positivity), and 2% were latently infected with tuberculosis. We found 30% infected with pathogenic intestinal parasites. Only 46% had serologic evidence of immunisation against HBV.CONCLUSION: The prevalence of infections in IAC was lower than previously reported but compared to the general population, a higher prevalence of intestinal parasites, hepatitis and tuberculosis was found. We recommend that IAC are offered screening shortly after arrival.

AB - AIM: To show the prevalence of selected infectious diseases among internationally adopted children (IAC) in Denmark.BACKGROUND: Each year approximately 200 IAC arrive in Denmark. These are at increased risk of infectious diseases rarely seen in Danish children. Studies from the 1990s showed that 60% of IAC had infectious diseases and that the majority of these were undetected without screening.METHODS: The study is a prospective study of medical records from children seen in the adoption clinic at Copenhagen University Hospital in the period 2009-2013. Screening was done for hepatitis A (HAV), B (HBV) and C (HCV), syphilis, HIV, tuberculosis (TB) and intestinal parasites.RESULTS: In 245 IAC tested, 2% had evidence of recent HAV infection, 3% with HBV and one child with HCV, and no cases of HIV were found. One child had antibodies against syphilis (anti-Trpa AB positivity), and 2% were latently infected with tuberculosis. We found 30% infected with pathogenic intestinal parasites. Only 46% had serologic evidence of immunisation against HBV.CONCLUSION: The prevalence of infections in IAC was lower than previously reported but compared to the general population, a higher prevalence of intestinal parasites, hepatitis and tuberculosis was found. We recommend that IAC are offered screening shortly after arrival.

KW - adoptees

KW - hepatitis A

KW - hepatitis B

KW - infectious diseases

KW - intestinal parasites

KW - tuberculosis

U2 - 10.1111/apa.15045

DO - 10.1111/apa.15045

M3 - Journal article

C2 - 31580515

VL - 109

SP - 1004

EP - 1010

JO - Acta paediatrica

JF - Acta paediatrica

SN - 1651-2227

IS - 5

ER -

ID: 58927571