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Rigshospitalet - en del af Københavns Universitetshospital
Udgivet

Glomerular Filtration Rate Estimation in Renal and Non-Renal Solid Organ Transplantation

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

DOI

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Vis graf over relationer

Following transplantation (TX) of both renal and non-renal organs, a large proportion of patients have renal dysfunction. There are multiple causes for this. Chronic nephrotoxicity and high doses of calcineurin inhibitors are important factors. Preoperative and perioperative factors like hypertension, hypotension, drugs and infections may play a causative role as well. Organ-specific causes include hepatorenal syndrome, cirrhosis, low cardiac function, low respiratory function and diabetes developed both before and after TX. It is important to be able to perform precise and valid measurements or estimates of renal function in these patients, in order to accurately and safely dose immunosuppressive medication and perform and adjust the treatment and prophylaxis of renal dysfunction. This is a short overview and discussion of relevant studies and possible caveats of estimated glomerular filtration rate methods for use in renal and non-renal TX.

OriginalsprogEngelsk
TidsskriftNephron
Vol/bind136
Udgave nummer4
Sider (fra-til)298-301
Antal sider4
ISSN1660-8151
DOI
StatusUdgivet - 2017

ID: 49587746