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Frequency of fatigue and its changes in the first 6 months after traumatic brain injury: results from the CENTER-TBI study

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Harvard

Andelic, N, Røe, C, Brunborg, C, Zeldovich, M, Løvstad, M, Løke, D, Borgen, IM, Voormolen, DC, Howe, EI, Forslund, MV, Dahl, HM, von Steinbuechel, N, CENTER-TBI participants investigators & Kondziella, D 2021, 'Frequency of fatigue and its changes in the first 6 months after traumatic brain injury: results from the CENTER-TBI study', Journal of Neurology, bind 268, nr. 1, s. 61-73. https://doi.org/10.1007/s00415-020-10022-2

APA

Andelic, N., Røe, C., Brunborg, C., Zeldovich, M., Løvstad, M., Løke, D., Borgen, I. M., Voormolen, D. C., Howe, E. I., Forslund, M. V., Dahl, H. M., von Steinbuechel, N., CENTER-TBI participants investigators, & Kondziella, D. (2021). Frequency of fatigue and its changes in the first 6 months after traumatic brain injury: results from the CENTER-TBI study. Journal of Neurology, 268(1), 61-73. https://doi.org/10.1007/s00415-020-10022-2

CBE

Andelic N, Røe C, Brunborg C, Zeldovich M, Løvstad M, Løke D, Borgen IM, Voormolen DC, Howe EI, Forslund MV, Dahl HM, von Steinbuechel N, CENTER-TBI participants investigators, Kondziella D. 2021. Frequency of fatigue and its changes in the first 6 months after traumatic brain injury: results from the CENTER-TBI study. Journal of Neurology. 268(1):61-73. https://doi.org/10.1007/s00415-020-10022-2

MLA

Vancouver

Author

Andelic, Nada ; Røe, Cecilie ; Brunborg, Cathrine ; Zeldovich, Marina ; Løvstad, Marianne ; Løke, Daniel ; Borgen, Ida M ; Voormolen, Daphne C ; Howe, Emilie I ; Forslund, Marit V ; Dahl, Hilde M ; von Steinbuechel, Nicole ; CENTER-TBI participants investigators ; Kondziella, Daniel. / Frequency of fatigue and its changes in the first 6 months after traumatic brain injury : results from the CENTER-TBI study. I: Journal of Neurology. 2021 ; Bind 268, Nr. 1. s. 61-73.

Bibtex

@article{8477c93f8b314d2d90cf6585825f59c2,
title = "Frequency of fatigue and its changes in the first 6 months after traumatic brain injury: results from the CENTER-TBI study",
abstract = "BACKGROUND: Fatigue is one of the most commonly reported subjective symptoms following traumatic brain injury (TBI). The aims were to assess frequency of fatigue over the first 6 months after TBI, and examine whether fatigue changes could be predicted by demographic characteristics, injury severity and comorbidities.METHODS: Patients with acute TBI admitted to 65 trauma centers were enrolled in the study Collaborative European NeuroTrauma Effectiveness Research in TBI (CENTER-TBI). Subjective fatigue was measured by single item on the Rivermead Post-Concussion Symptoms Questionnaire (RPQ), administered at baseline, three and 6 months postinjury. Patients were categorized by clinical care pathway: admitted to an emergency room (ER), a ward (ADM) or an intensive care unit (ICU). Injury severity, preinjury somatic- and psychiatric conditions, depressive and sleep problems were registered at baseline. For prediction of fatigue changes, descriptive statistics and mixed effect logistic regression analysis are reported.RESULTS: Fatigue was experienced by 47% of patients at baseline, 48% at 3 months and 46% at 6 months. Patients admitted to ICU had a higher probability of experiencing fatigue than those in ER and ADM strata. Females and individuals with lower age, higher education, more severe intracranial injury, preinjury somatic and psychiatric conditions, sleep disturbance and feeling depressed postinjury had a higher probability of fatigue.CONCLUSION: A high and stable frequency of fatigue was found during the first 6 months after TBI. Specific socio-demographic factors, comorbidities and injury severity characteristics were predictors of fatigue in this study.",
keywords = "Head injury, Longitudinal studies, Neurological disorders, Post-traumatic fatigue",
author = "Nada Andelic and Cecilie R{\o}e and Cathrine Brunborg and Marina Zeldovich and Marianne L{\o}vstad and Daniel L{\o}ke and Borgen, {Ida M} and Voormolen, {Daphne C} and Howe, {Emilie I} and Forslund, {Marit V} and Dahl, {Hilde M} and {von Steinbuechel}, Nicole and {CENTER-TBI participants investigators} and Daniel Kondziella",
year = "2021",
month = jan,
doi = "10.1007/s00415-020-10022-2",
language = "English",
volume = "268",
pages = "61--73",
journal = "Journal of Neurology",
issn = "0340-5354",
publisher = "Dr. Dietrich/Steinkopff Verlag",
number = "1",

}

RIS

TY - JOUR

T1 - Frequency of fatigue and its changes in the first 6 months after traumatic brain injury

T2 - results from the CENTER-TBI study

AU - Andelic, Nada

AU - Røe, Cecilie

AU - Brunborg, Cathrine

AU - Zeldovich, Marina

AU - Løvstad, Marianne

AU - Løke, Daniel

AU - Borgen, Ida M

AU - Voormolen, Daphne C

AU - Howe, Emilie I

AU - Forslund, Marit V

AU - Dahl, Hilde M

AU - von Steinbuechel, Nicole

AU - CENTER-TBI participants investigators

A2 - Kondziella, Daniel

PY - 2021/1

Y1 - 2021/1

N2 - BACKGROUND: Fatigue is one of the most commonly reported subjective symptoms following traumatic brain injury (TBI). The aims were to assess frequency of fatigue over the first 6 months after TBI, and examine whether fatigue changes could be predicted by demographic characteristics, injury severity and comorbidities.METHODS: Patients with acute TBI admitted to 65 trauma centers were enrolled in the study Collaborative European NeuroTrauma Effectiveness Research in TBI (CENTER-TBI). Subjective fatigue was measured by single item on the Rivermead Post-Concussion Symptoms Questionnaire (RPQ), administered at baseline, three and 6 months postinjury. Patients were categorized by clinical care pathway: admitted to an emergency room (ER), a ward (ADM) or an intensive care unit (ICU). Injury severity, preinjury somatic- and psychiatric conditions, depressive and sleep problems were registered at baseline. For prediction of fatigue changes, descriptive statistics and mixed effect logistic regression analysis are reported.RESULTS: Fatigue was experienced by 47% of patients at baseline, 48% at 3 months and 46% at 6 months. Patients admitted to ICU had a higher probability of experiencing fatigue than those in ER and ADM strata. Females and individuals with lower age, higher education, more severe intracranial injury, preinjury somatic and psychiatric conditions, sleep disturbance and feeling depressed postinjury had a higher probability of fatigue.CONCLUSION: A high and stable frequency of fatigue was found during the first 6 months after TBI. Specific socio-demographic factors, comorbidities and injury severity characteristics were predictors of fatigue in this study.

AB - BACKGROUND: Fatigue is one of the most commonly reported subjective symptoms following traumatic brain injury (TBI). The aims were to assess frequency of fatigue over the first 6 months after TBI, and examine whether fatigue changes could be predicted by demographic characteristics, injury severity and comorbidities.METHODS: Patients with acute TBI admitted to 65 trauma centers were enrolled in the study Collaborative European NeuroTrauma Effectiveness Research in TBI (CENTER-TBI). Subjective fatigue was measured by single item on the Rivermead Post-Concussion Symptoms Questionnaire (RPQ), administered at baseline, three and 6 months postinjury. Patients were categorized by clinical care pathway: admitted to an emergency room (ER), a ward (ADM) or an intensive care unit (ICU). Injury severity, preinjury somatic- and psychiatric conditions, depressive and sleep problems were registered at baseline. For prediction of fatigue changes, descriptive statistics and mixed effect logistic regression analysis are reported.RESULTS: Fatigue was experienced by 47% of patients at baseline, 48% at 3 months and 46% at 6 months. Patients admitted to ICU had a higher probability of experiencing fatigue than those in ER and ADM strata. Females and individuals with lower age, higher education, more severe intracranial injury, preinjury somatic and psychiatric conditions, sleep disturbance and feeling depressed postinjury had a higher probability of fatigue.CONCLUSION: A high and stable frequency of fatigue was found during the first 6 months after TBI. Specific socio-demographic factors, comorbidities and injury severity characteristics were predictors of fatigue in this study.

KW - Head injury

KW - Longitudinal studies

KW - Neurological disorders

KW - Post-traumatic fatigue

UR - http://www.scopus.com/inward/record.url?scp=85088051993&partnerID=8YFLogxK

U2 - 10.1007/s00415-020-10022-2

DO - 10.1007/s00415-020-10022-2

M3 - Journal article

C2 - 32676767

VL - 268

SP - 61

EP - 73

JO - Journal of Neurology

JF - Journal of Neurology

SN - 0340-5354

IS - 1

ER -

ID: 61294334