Forskning
Udskriv Udskriv
Switch language
Rigshospitalet - en del af Københavns Universitetshospital
Udgivet

Fatigue, physical activity and associated factors in 779 patients with myasthenia gravis

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

DOI

  1. Results of an open label feasibility study of sodium valproate in people with McArdle disease

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Contractile properties are impaired in congenital myopathies

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. No effect of oral sucrose or IV glucose during exercise in phosphorylase b kinase deficiency

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. Quantitative Muscle MRI and Clinical Findings in Women With Pathogenic Dystrophin Gene Variants

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Myopathy can be a key phenotype of membrin (GOSR2) deficiency

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Cardiac Involvement in Women With Pathogenic Dystrophin Gene Variants

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  4. Efficacy and Safety of Rozanolixizumab in Moderate to Severe Generalized Myasthenia Gravis: A Phase 2 Randomized Control Trial

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  5. Episodic hyperCKaemia may be a feature of α-methylacyl-coenzyme A racemase deficiency

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Vis graf over relationer

The objective of the study was to examine the association between fatigue (measured by the Multidimensional Fatigue Inventory; MFI-20) and physical activity (measured by the Saltin-Grimby Physical Activity Level Scale; SGPALS) in a large cohort of patients (≥18 years) with myasthenia gravis (MG) including relevant disease - and lifestyle-related factors. A total of 1463 persons, registered at the Danish National Registry of Patients with a MG diagnosis, according to the International Classification of Diseases, received a web-based survey. A total of 779 patients (53% women, mean [SD] age 60.8 [15.5]) responded. The remaining persons were either non-responders (n = 390) or could not confirm the MG diagnosis (n = 294). The most prominent MFI-20 fatigue domains were general fatigue (median [inter-quartile ranges, IQR], 13 [10-16]) and physical fatigue (median [IQR], 13 [9-15]), and 386 (53%) patients reported low levels of physical activity. All fatigue domains were associated with physical activity (p<.01). Higher level of physical activity was associated with lower levels of fatigue. Important factors for the association were myasthenia gravis disease severity (measured by the Myasthenia Gravis Activities of Daily Living profile), body mass index, insomnia (measured by the Insomnia Severity Index) job-status, comorbidity, and cohabitation.

OriginalsprogEngelsk
TidsskriftNeuromuscular disorders : NMD
Vol/bind31
Udgave nummer8
Sider (fra-til)716-725
Antal sider10
ISSN0960-8966
DOI
StatusUdgivet - aug. 2021

ID: 67442459