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Rigshospitalet - en del af Københavns Universitetshospital
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Extremely Preterm Infant Admissions Within the SafeBoosC-III Consortium During the COVID-19 Lockdown

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

DOI

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  • Marie Isabel Rasmussen
  • Mathias Lühr Hansen
  • Gerhard Pichler
  • Eugene Dempsey
  • Adelina Pellicer
  • Afif EL-Khuffash
  • Shashidhar A
  • Salvador Piris-Borregas
  • Miguel Alsina
  • Merih Cetinkaya
  • Lina Chalak
  • Hilal Özkan
  • Mariana Baserga
  • Jan Sirc
  • Hans Fuchs
  • Ebru Ergenekon
  • Luis Arruza
  • Amit Mathur
  • Martin Stocker
  • Olalla Otero Vaccarello
  • Tomasz Szczapa
  • Kosmas Sarafidis
  • Barbara Królak-Olejnik
  • Asli Memisoglu
  • Hallvard Reigstad
  • Elżbieta Rafińska-Ważny
  • Eleftheria Hatzidaki
  • Zhang Peng
  • Despoina Gkentzi
  • Renaud Viellevoye
  • Julie De Buyst
  • Emmanuele Mastretta
  • Ping Wang
  • Gitte Holst Hahn
  • Lars Bender
  • Luc Cornette
  • Jakub Tkaczyk
  • Ruth del Rio
  • Monica Fumagalli
  • Evangelia Papathoma
  • Maria Wilinska
  • Gunnar Naulaers
  • Iwona Sadowska-Krawczenko
  • Chantal Lecart
  • María Luz Couce
  • Siv Fredly
  • Anne Marie Heuchan
  • Tanja Karen
  • Gorm Greisen
Vis graf over relationer

Objective: To evaluate if the number of admitted extremely preterm (EP) infants (born before 28 weeks of gestational age) differed in the neonatal intensive care units (NICUs) of the SafeBoosC-III consortium during the global lockdown when compared to the corresponding time period in 2019. Design: This is a retrospective, observational study. Forty-six out of 79 NICUs (58%) from 17 countries participated. Principal investigators were asked to report the following information: (1) Total number of EP infant admissions to their NICU in the 3 months where the lockdown restrictions were most rigorous during the first phase of the COVID-19 pandemic, (2) Similar EP infant admissions in the corresponding 3 months of 2019, (3) the level of local restrictions during the lockdown period, and (4) the local impact of the COVID-19 lockdown on the everyday life of a pregnant woman. Results: The number of EP infant admissions during the first wave of the COVID-19 pandemic was 428 compared to 457 in the corresponding 3 months in 2019 (−6.6%, 95% CI −18.2 to +7.1%, p = 0.33). There were no statistically significant differences within individual geographic regions and no significant association between the level of lockdown restrictions and difference in the number of EP infant admissions. A post-hoc analysis based on data from the 46 NICUs found a decrease of 10.3%in the total number of NICU admissions (n = 7,499 in 2020 vs. n = 8,362 in 2019). Conclusion: This ad hoc study did not confirm previous reports of a major reduction in the number of extremely pretermbirths during the first phase of the COVID-19 pandemic. Clinical Trial Registration: ClinicalTrial.gov, identifier: NCT04527601 (registered August 26, 2020), https://clinicaltrials.gov/ct2/show/NCT04527601.

OriginalsprogEngelsk
Artikelnummer647880
TidsskriftFrontiers in Pediatrics
Vol/bind9
ISSN2296-2360
DOI
StatusUdgivet - 12 jul. 2021

ID: 67283183