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"Development in well-being and social function among Danish hemophilia patients with HIV: a three-wave panel study spanning 24 years"

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review


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  • Emilie B Ingvorsen
  • Christina Schnohr
  • Terkel Andersen
  • Lars Lehrmann
  • Eva Funding
  • Lone H Poulsen
  • Karen B Holm
  • Alex L Laursen
  • Jan Gerstoft
  • Jakob B Bjorner
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BACKGROUND: Between 1975 and 1985 a total of 91 Danish patients with moderate and severe hemophilia (PWH) was infected with HIV constituting a major scandal in the Danish health care system. This study describes the burden of HIV infection among Danish PWH by evaluating changes from 1988 to 2012 in well-being, social function, experiencing stigma and openness about disease among Danish HIV+ PWH.

METHODS: Three anonymous surveys were conducted in 1988, 2001 and 2012 targeting all Danish patients with moderate to severe hemophilia. Survey responses were received from 53, 21 and 18 HIV+ PWH respectively. A matched comparison sample of HIV- PWH was identified for each survey-year, using propensity score matching. Differences for each survey-year and trends over time were analyzed using ordinal logistic regression.

RESULTS: In 1988, HIV+ PWH had more psychosomatic symptoms than HIV- PWH, but in 2001 life satisfaction was higher among HIV+ PWH than among HIV- PWH. Tests of differences in trend over time showed larger improvements in life satisfaction among HIV+ PWH than HIV- PWH, while HIV- PWH showed an increase in educational level compared to HIV+ PWH. Analysis restricted to HIV+ PWH showed an increase in perceived stigmatization.

CONCLUSIONS: Differences between Danish HIV+ and HIV- PWH regarding well-being and psychosomatic symptoms seem to have evened out between 1988 and 2012. However, results suggest that HIV+ PWH still experience stigmatization and lower levels of education.

TidsskriftBMC Public Health
Udgave nummer1
Sider (fra-til)1714
StatusUdgivet - 19 dec. 2019

ID: 59436561