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Rigshospitalet - en del af Københavns Universitetshospital
E-pub ahead of print

Correlation between immunoglobulin dose administered and plasma neutralization of streptococcal superantigens in patients with necrotizing soft tissue infections

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

DOI

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  • INFECT study group
Vis graf over relationer

Analyses of plasma collected pre- and post-administration of intravenous immunoglobulin G (IVIG) from patients with Group A Streptococcus necrotizing soft tissue infections demonstrated a negative correlation between IVIG dose and toxin-triggered T-cell proliferation (r=-0.67, p<0.0001). One 25g-dose IVIG was sufficient to yield patient plasma neutralizing activity against streptococcal superantigens.

OriginalsprogEngelsk
TidsskriftClinical infectious diseases : an official publication of the Infectious Diseases Society of America
ISSN1058-4838
DOI
StatusE-pub ahead of print - 9 jan. 2020

Bibliografisk note

© The Author(s) 2020. Published by Oxford University Press for the Infectious Diseases Society of America.

ID: 59138287