Forskning
Udskriv Udskriv
Switch language
Rigshospitalet - en del af Københavns Universitetshospital
Udgivet

Comparison of refractive predictability and endothelial cell loss in femtosecond laser-assisted cataract surgery and conventional phaco surgery: prospective randomised trial with 6 months of follow-up

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. Danish teleophthalmology platform reduces optometry referrals into the national eye care system

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Povidone iodine treatment is deleterious to human ocular surface conjunctival cells in culture

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Clinical and genomic features of adult and paediatric acute leukaemias with ophthalmic manifestations

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  4. Inverted papilloma of the conjunctiva

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. Detection of oedema on optical coherence tomography images using deep learning model trained on noisy clinical data

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Modelling and prognostication of growth in the number of patients treated for neovascular age-related macular degeneration

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. The learning curve of robot-assisted vitreoretinal surgery - A randomized trial in a simulated setting

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  4. Defining the surgical footprint in cataract surgery: patient-related outcomes dependent on the experience of the surgeon

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Vis graf over relationer

Objective: Femtosecond laser-assisted cataract surgery (FLACS) decreases the use of energy and provides a more precise capsulorhexis compared with conventional phaco surgery (CPS). The purpose of this study was to examine if the lower energy use in FLACS caused less endothelial cell loss compared with CPS and if there was a difference in refractive predictability between CPS and FLACS.

Methods and analysis: This was a randomised controlled study of 96 patients with a 6-month follow-up comparing one eye surgery by FLACS and the contralateral eye operated by CPS (divide and conquer technique). Both eyes had intraocular aspheric lenses implanted. Uncorrected distance visual acuity, corrected distance visual acuity (CDVA), central corneal endothelial cell count and hexagonality (non-contact endothelial cell microscope) were assessed preoperatively at 40 and at 180 days postoperatively.

Results: The mean phaco energies were 6.55 (95% CI 5.43 to 7.66) and 9.77 (95% CI 8.55 to 10.95) U/S (p<0.0001) by FLACS and CPS, respectively. At day 40, the mean endothelial cell loss (ECL) was 344 cells/mm2 (95% CI 245 to 443) by FLACS (12.89%) and 497 cells/mm2 (95% CI 380 to 614) by CPS (18.19%) (p=0.027). At day 180, ECL was 362 cells/mm2 (95% CI 275 to 450) in FLACS (13.56%) and 465 cells/mm2 (95% CI 377 to 554) in CPS (17.03%) (p=0.036).The mean absolute difference from the attempted refraction was 0.43 (95% CI 0.36 to 0.51) dioptres (D) at day 40 and 0.46 D (95% CI 0.39 to 0.53) at day 180 by FLACS compared with 0.43 D (95% CI 0.36 to 0.51) at day 40 (p=0.95) and 0.46 D (95% CI 0.37 to 0.52) at day 180 (p=0.91) with CPS.

Conclusion: ECL was significantly lower in FLACS compared with CPS at both day 40 and day 180. ECL was correlated to the energy used. We found no difference in refractive predictability or CDVA between the groups.

OriginalsprogEngelsk
TidsskriftBMJ Open Ophthalmology
Vol/bind4
Udgave nummer1
Sider (fra-til)e000233
ISSN2397-3269
DOI
StatusUdgivet - 2019

ID: 59166192