Forskning
Udskriv Udskriv
Switch language
Rigshospitalet - en del af Københavns Universitetshospital
Udgivet

Clinicopathologic characteristics of Burkitt lymphoma of the head and neck in a non-endemic region-a Danish nationwide study

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. Danish translation of the Neck Dissection Impairment Index

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Distribution of microcrack surface density in the human otic capsule

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. Posterior uveal melanoma incidence and survival by AJCC tumour size in a 70-year nationwide cohort

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Ultraviolet radiation drives mutations in a subset of mucosal melanomas

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Genomic Alterations in Human Papillomavirus-Positive and -Negative Conjunctival Squamous Cell Carcinomas

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  4. Increments in DNA-thioguanine level during thiopurine enhanced maintenance therapy of acute lymphoblastic leukemia

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  5. Nasopharyngeal malignancies in Denmark diagnosed from 1980 to 2014

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Vis graf over relationer

BACKGROUND: Burkitt lymphoma rarely presents in head and neck (H&N) in Western countries.

AIMS/OBJECTIVES: We aimed to characterise clinicopathological features of H&N Burkitt lymphoma in Denmark representing a non-endemic region.

MATERIAL AND METHODS: Clinical records were reviewed for a nationwide cohort of patients diagnosed with H&N Burkitt lymphoma in Denmark between 1980 and 2018. The diagnosis was histologically validated.

RESULTS: Thirty-four patients with H&N Burkitt lymphoma (highest incidence in age group 0-9 years, male-to-female ratio 4.7:1) were included. Thirty-three lymphomas (97%) were extranodal. The tumour was visible at the clinical examination in 81% (n = 22) of the cases. The palatine tonsils were the most frequent location (n = 13, 38%) and 52% (n = 17) of the patients were diagnosed in advanced stage. Lymphoma was the tentative clinical diagnosis in 23% of the cases. The 5-year overall- and disease-specific survival was 78% and 81%, respectively.

CONCLUSIONS: Due to the rarity of Burkitt lymphoma of the H&N, there is a high risk of clinical misdiagnosis. Our findings suggest which symptoms and clinical presentations to be aware of in the diagnostics work up that could lead to the diagnosis of Burkitt lymphoma.

OriginalsprogEngelsk
TidsskriftActa Oto-Laryngologica
Vol/bind141
Udgave nummer8
Sider (fra-til)812-819
Antal sider8
ISSN0001-6489
DOI
StatusUdgivet - aug. 2021

ID: 67742361