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Rigshospitalet - en del af Københavns Universitetshospital
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Characteristics and early outcomes of patients hospitalised for COVID-19 in North Zealand, Denmark

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  • Maria Elisabeth Lendorf
  • Mogens Karsbøl Boisen
  • Peter Lommer Kristensen
  • Ellen Christine Leth Løkkegaard
  • Sebastian Moretto Krog
  • Lisbet Brandi
  • Louise Schouborg Brinth
  • Rúna Louise Mortansdóttir Nolsöe
  • Camilla Ryrsø
  • Pia Eiken
  • Morten Heiberg Bestle
  • Inger Merete Jørgensen
  • Ulrik Pedersen-Bjergaard
  • Birgitte Lindegaard
  • Thomas Broe Christensen
  • Thea Kølsen Fischer
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INTRODUCTION: Coronavirus disease 2019 (COVID-19) is an ongoing pandemic associated with significant morbidity and mortality worldwide. Limited data are available describing the clinical presentation and outcomes of hospitalised COVID-19 patients in Europe.

METHODS: This was a single-centre retrospective chart review of all patients with COVID-19 admitted to the North Zealand Hospital in Denmark between 1 March and 4 May 2020. Main outcomes include major therapeutic interventions during hospitalisation, such as invasive mechanical ventilation, as well as death.

RESULTS: A total of 115 patients were included, including four infants. The median age of adults was 68 years and 40% were female. At admission, 55 (50%) patients had a fever, 29 (26%) had a respiratory rate exceeding 24 breaths/minute, and 78 (70%) received supplemental oxygen. The prevalence of co-infection was 13%. Twenty patients (18%) (median age: 64 years; 15% female) were treated in the intensive care unit. Twelve (10.4%) received invasive mechanical ventilation and three (2.6%) renal replacement therapy. Nine patients (8%) developed pulmonary embolism. Sixteen patients (14%) died. Among patients requiring mechanical ventilation (n = 12), seven (6.1%) were discharged alive, four (3.4%) died and one (0.9%) was still hospitalised.

CONCLUSION: In this cohort of hospitalised COVID-19 patients, mortality was lower than in other Danish and European case series.

FUNDING: none.

TRIAL REGISTRATION: not relevant.

OriginalsprogEngelsk
ArtikelnummerA06200428
TidsskriftDanish Medical Journal
Vol/bind67
Udgave nummer9
ISSN1603-9629
StatusUdgivet - 2020

Bibliografisk note

Articles published in the DMJ are “open access”. This means that the articles are distributed under the terms of the Creative Commons Attribution Non-commercial License, which permits any non-commercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.

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