Forskning
Udskriv Udskriv
Switch language
Rigshospitalet - en del af Københavns Universitetshospital
Udgivet

Burden and attitude to resistant and refractory migraine: a survey from the European Headache Federation with the endorsement of the European Migraine & Headache Alliance

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

DOI

  1. The chronobiology of migraine: a systematic review

    Publikation: Bidrag til tidsskriftReviewForskningpeer review

  2. Investigation of cortical thickness and volume during spontaneous attacks of migraine without aura: a 3-Tesla MRI study

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Reference programme: diagnosis and treatment of headache disorders and facial pain. Danish Headache Society, 3rd edition, 2020

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  4. Delayed headache after COVID-19 vaccination: a red flag for vaccine induced cerebral venous thrombosis

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. Hormonal influences in migraine - interactions of oestrogen, oxytocin and CGRP

    Publikation: Bidrag til tidsskriftReviewForskningpeer review

  2. CGRP and migraine; from bench to bedside

    Publikation: Bidrag til tidsskriftReviewForskningpeer review

  3. Pre-Chiasmatic, Single Injection of Autologous Blood to Induce Experimental Subarachnoid Hemorrhage in a Rat Model

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  4. Identifying New Antimigraine Targets: Lessons from Molecular Biology

    Publikation: Bidrag til tidsskriftReviewForskningpeer review

  • Simona Sacco
  • Christian Lampl
  • Antoinette Maassen van den Brink
  • Valeria Caponnetto
  • Mark Braschinsky
  • Anne Ducros
  • Patrick Little
  • Patricia Pozo-Rosich
  • Uwe Reuter
  • Elena Ruiz de la Torre
  • Margarita Sanchez Del Rio
  • Alexandra J Sinclair
  • Paolo Martelletti
  • Zaza Katsarava
  • Burden and Attitude to Resistant and Refractory (BARR) Study Group
  • Lars Edvinsson (Medlem af forfattergruppering)
Vis graf over relationer

BACKGROUND: New treatments are currently offering new opportunities and challenges in clinical management and research in the migraine field. There is the need of homogenous criteria to identify candidates for treatment escalation as well as of reliable criteria to identify refractoriness to treatment. To overcome those issues, the European Headache Federation (EHF) issued a Consensus document to propose criteria to approach difficult-to-treat migraine patients in a standardized way. The Consensus proposed well-defined criteria for resistant migraine (i.e., patients who do not respond to some treatment but who have residual therapeutic opportunities) and refractory migraine (i.e., patients who still have debilitating migraine despite maximal treatment efforts). The aim of this study was to better understand the perceived impact of resistant and refractory migraine and the attitude of physicians involved in migraine care toward those conditions.

METHODS: We conducted a web-questionnaire-based cross-sectional international study involving physicians with interest in headache care.

RESULTS: There were 277 questionnaires available for analysis. A relevant proportion of participants reported that patients with resistant and refractory migraine were frequently seen in their clinical practice (49.5% for resistant and 28.9% for refractory migraine); percentages were higher when considering only those working in specialized headache centers (75% and 46% respectively). However, many physicians reported low or moderate confidence in managing resistant (8.1% and 43.3%, respectively) and refractory (20.7% and 48.4%, respectively) migraine patients; confidence in treating resistant and refractory migraine patients was different according to the level of care and to the number of patients visited per week. Patients with resistant and refractory migraine were infrequently referred to more specialized centers (12% and 19%, respectively); also in this case, figures were different according to the level of care.

CONCLUSIONS: This report highlights the clinical relevance of difficult-to-treat migraine and the presence of unmet needs in this field. There is the need of more evidence regarding the management of those patients and clear guidance referring to the organization of care and available opportunities.

OriginalsprogEngelsk
Artikelnummer39
TidsskriftThe Journal of Headache and Pain Online
Vol/bind22
Udgave nummer1
Sider (fra-til)39
Antal sider1
ISSN1129-2377
DOI
StatusUdgivet - dec. 2021

ID: 65837948