Forskning
Udskriv Udskriv
Switch language
Rigshospitalet - en del af Københavns Universitetshospital
Udgivet

Autologous versus implant-based breast reconstruction: A systematic review and meta-analysis of Breast-Q patient-reported outcomes

Publikation: Bidrag til tidsskriftReviewForskningpeer review

DOI

  1. Delayed two-stage breast reconstruction: The impact of radiotherapy

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Efficacy of breast reconstruction with fat grafting: A systematic review and meta-analysis

    Publikation: Bidrag til tidsskriftReviewForskningpeer review

  1. Indocyanine green guided mastectomy and immediate breast reconstruction

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. TLR9 agonist MGN1703 enhances B cell differentiation and function in lymph nodes

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Vis graf over relationer

OBJECTIVE: Breast reconstruction following mastectomy can increase the quality of life of patients. Reconstruction methods can broadly be divided into implant-based and autologous tissue reconstruction. Patient-reported outcomes following breast reconstruction are one of the most important success parameters. In this systematic review and meta-analysis, we aimed to compare the two methods using the recognized Breast-Q questionnaire.

METHODS: We performed a systematic search in PubMed and EMBASE databases. Meta-analysis was performed on the five most commonly reported Breast-Q modules. RevMan 5.3 was used for statistical analysis. Methodological quality of the included studies was assessed using the Newcastle-Ottawa Quality Assessment Form for Cohort Studies.

RESULTS: The search strategy resulted in 219 studies of which nine studies were included in the analysis, yielding 2129 implant-based and 825 autologous breast reconstructions. Overall satisfaction with outcome as well as breast was significantly higher among patients with autologous breast reconstructions (mean Breast-Q difference between the two groups was 9.82 [3.09, 16.54], p = 0.004, and 10.33 [95% CI 5.93, 14.74], p<0.00001, respectively). Sexual and psychosocial well-being was higher among autologous breast reconstructions. There was no difference in the physical well-being.

CONCLUSION: This is the first systematic review and meta-analysis to compare patient-reported outcomes of implant-based and autologous breast reconstruction. We found that autologous reconstruction yields a higher satisfaction with overall outcome and breast. These findings can aid clinicians when discussing breast reconstruction options with patients.

OriginalsprogEngelsk
TidsskriftJournal of plastic, reconstructive & aesthetic surgery : JPRAS
Vol/bind73
Udgave nummer2
Sider (fra-til)278-285
ISSN1748-6815
DOI
StatusUdgivet - feb. 2020

Bibliografisk note

Copyright © 2019 Elsevier Ltd. All rights reserved.

ID: 59181922