Forskning
Udskriv Udskriv
Switch language
Rigshospitalet - en del af Københavns Universitetshospital
Udgivet

Association between head and neck cancer and sexually transmitted diseases: a Danish nationwide, case-control study

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. Nordic results of cochlear implantation in adults: speech perception and patient reported outcomes

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Development of depression in patients with oral cavity cancer: a systematic review

    Publikation: Bidrag til tidsskriftReviewForskningpeer review

  3. Transoral robotic surgery: a 4-year learning experience in a single Danish Cancer Centre

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. The molecular profile of mucosal melanoma

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Outcome in patients with isolated regional recurrence after primary radiotherapy for head and neck cancer

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Vis graf over relationer

Background: An association between sexually transmitted diseases (STDs) and occurrence of head and neck cancer (HNC) is proposed.Aims/objectives: We aimed to determine the association between selected STDs (syphilis, gonorrhoea, HIV) and HNC.Materials and methods: Patients diagnosed with HNC in Denmark between 1978 and 2014 identified through the Danish Cancer Registry were included. Patients were age- and sex-matched in a 1:10 ratio with general population controls. Uni- and multivariate analyses were performed using the Cox regression model to assess the correlation between STD and HNC.Results: A total of 39,405 HNC patients (63% men; 63.0 years at HNC diagnosis) and 393,238 controls were included. STD in HNC patients was 0.27%, vs. 0.11% in controls. Patients with cancer of the upper airways had a significantly higher prevalence of an STD prior to the HNC compared to controls. Most HNC patients with a prior STD (64.1%) developed the HNC within five years after the STD diagnosis.Conclusions: Although the studied STDs are rare, patients with cancer of the upper aerodigestive tract more commonly had a previous diagnosis of STD compared to controls. The study promotes the hypothesis that a causal link exists between STD and HNC.

OriginalsprogEngelsk
TidsskriftActa Oto-Laryngologica
Vol/bind140
Udgave nummer7
Sider (fra-til)615-619
Antal sider5
ISSN0001-6489
DOI
StatusUdgivet - jul. 2020

ID: 59838905