Forskning
Udskriv Udskriv
Switch language
Rigshospitalet - en del af Københavns Universitetshospital
Udgivet

Association between Hashimoto's Thyroiditis and Thyroid Cancer in 64,628 Patients

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

DOI

  1. An Extended Hypofractionated Palliative Radiotherapy Regimen for Head and Neck Carcinomas

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Cohort Profile: The Danish Testicular Cancer Late Treatment Effects Cohort (DaTeCa-LATE)

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Symptom Burden and Palliative Referral Disparities in an Ambulatory South Texas Cancer Center

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. Safety of switching to Migalastat from enzyme replacement therapy in Fabry disease: Experience from the Phase 3 ATTRACT study

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Intratumor heterogeneity of PD-L1 expression in head and neck squamous cell carcinoma

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Cerebral infarction after fractionated stereotactic radiation therapy of benign anterior skull base tumors

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  4. Completeness of RET testing in patients with medullary thyroid carcinoma in Denmark 1997-2013: a nationwide study

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Vis graf over relationer

BACKGROUND: The incidence of thyroid cancer (TC) is increasing although explanatory causes are lacking. A link between cancer and inflammation is well documented but unclear for autoimmune thyroid diseases and TC. We aimed to systematically review the association between Hashimoto's thyroiditis (HT) and papillary, follicular, medullary, anaplastic thyroid carcinoma, and thyroid lymphoma (TL).

METHODS: PubMed, OVID Medline, Google Scholar, and the Cochrane Library were searched from 1955 to 2016. The inclusion criteria were age >18 years, ≥20 cases of HT or TC. We collectively examined the incidence of HT in TC and of TC in HT.

RESULTS: We identified 36 studies (64,628 subjects) published between 1955 and 2016 from 13 countries. We found a relative risk (RR) of HT among papillary thyroid cancer (PTC) of 2.36 [95% confidence intervals (CIs) 1.55-3.29, p < 0.001], an RR of PTC among HT of 1.40 (95% CI 1.07-1.85, p = 0.016), and an RR of TL among HT of 9.74 (95% CI 3.93-24.13, p < 0.001).

CONCLUSION: We report an association between HT and PTC and between HT and TL. No association was found between HT and follicular, medullary, or anaplastic thyroid cancer.

OriginalsprogEngelsk
TidsskriftFrontiers in Oncology
Vol/bind7
Sider (fra-til)e53
ISSN2234-943X
DOI
StatusUdgivet - 2017

ID: 51549567