Forskning
Udskriv Udskriv
Switch language
Rigshospitalet - en del af Københavns Universitetshospital
Udgivet

Apparently conclusive meta-analyses may be inconclusive--Trial sequential analysis adjustment of random error risk due to repetitive testing of accumulating data in apparently conclusive neonatal meta-analyses

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

DOI

  1. Data Resource Profile: The Copenhagen Hospital Biobank (CHB)

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Male origin microchimerism and ovarian cancer

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Cross-trait analyses with migraine reveal widespread pleiotropy and suggest a vascular component to migraine headache

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  4. Cohort Profile: The Copenhagen Child Cohort Study (CCC2000)

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  5. Data Resource Profile: Committee of Nordic Assisted Reproductive Technology and Safety (CoNARTaS) cohort

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. Early specialised palliative care: interventions, symptoms, problems

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Was amorphous aluminium hydroxyphosphate sulfate adequately evaluated before authorisation in Europe?

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Low-dose hydrocortisone in patients with COVID-19 and severe hypoxia: the COVID STEROID randomised, placebo-controlled trial

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  4. Ongoing and future COVID-19 vaccine clinical trials: challenges and opportunities

    Publikation: Bidrag til tidsskriftReviewForskningpeer review

Vis graf over relationer
Random error may cause misleading evidence in meta-analyses. The required number of participants in a meta-analysis (i.e. information size) should be at least as large as an adequately powered single trial. Trial sequential analysis (TSA) may reduce risk of random errors due to repetitive testing of accumulating data by evaluating meta-analyses not reaching the information size with monitoring boundaries. This is analogous to sequential monitoring boundaries in a single trial.
OriginalsprogEngelsk
TidsskriftInternational Journal of Epidemiology
Vol/bind38
Udgave nummer1
Sider (fra-til)287-98
Antal sider12
ISSN0300-5771
DOI
StatusUdgivet - feb. 2009

ID: 38923291