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Rigshospitalet - en del af Københavns Universitetshospital

Deep phenotyping of the heart with advanced imaging modalities in type 2 diabetes – implications for pathophysiology and prognosis (DIA-HEART study)

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The purpose of this study is to identify patients with type 2 diabetes at high risk of developing cardiovascular disease and to get a better
understanding of the coexistence and interplay between diabetic kidney disease and severity of cardiovascular disease.
We will enroll 900 patients for a cardiac positron emission tomography (PET) scan. This is an imaging test that enable the calculation of 1)
the ability to increase blood flow in the heart during stress; 2) the calcification of the large vessels in the heart; and 3) the pump function of
the heart. After 5 years we will perform register-based follow-up and this will allow us to investigate the link between these three important
aspects of the function of the heart and development of cardiovascular disease.
In two sub studies, using new and advanced imaging methods, we will deeply characterize the structural and functional changes in the
vessels of the heart.

ID: 61654767