MD, PhD, DMSc
Expert in applied human molecular genetics. Expert areas include microscopic and submicroscopic structural variations (chromosome rearrangements, and submicroscopic copy number variations, CNVs) and their involvement in disease pathogenesis; intragenic small variations (mutations) and their association with human disorders. ZT has hands-on-experience on several laboratory techniques including chromosome analysis, chromosome microarray analyses, fluorescence in situ hybridization (FISH), gene cloning technologies, different DNA and RNA tecniques.
To identify genes and genetic/epigenetic mechanisms involved in monogenic and complex neurodevelopmental/
neuropsychiatric disorders: e.g. cloning of the Menkes disease gene, ATP7A; elucidation of the role of DYRK1A
in microcephaly; association of AADAC and IMMP2L in Tourette syndrome.
Identification of genes, genetic and epigenetic mechanisms involved different human disorders including:
ID: 36882422