Pattern recognition receptor polymorphisms in early periodontitis

Leite, F. R. M., Enevold, C., Bendtzen, K., Baelum, V. & López, R., jun. 2019, I : Journal of Periodontology. 90, 6, s. 647-654 8 s.

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Lewis and AB0 blood group-phenotypes in periodontitis, cardiovascular disease, obesity and stroke

Enevold, C., Nielsen, C. H., Molbo, D., Lund, R., Bendtzen, K., Fiehn, N-E. & Holmstrup, P., 2019, I : Scientific Reports. 9, 1, 7 s.

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Gasotransmitters and the immune system: Mode of action and novel therapeutic targets

Fagone, P., Mazzon, E., Bramanti, P., Bendtzen, K. & Nicoletti, F., 5 sep. 2018, I : European Journal of Pharmacology. 834, s. 92-102 11 s.

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Biological anti-TNF drugs: immunogenicity underlying treatment failure and adverse events

Prado, M. S., Bendtzen, K. & Andrade, L. E. C., sep. 2017, I : Expert Opinion on Drug Metabolism and Toxicology. 13, 9, s. 985-995 11 s.

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HIV-protease inhibitors for the treatment of cancer: Repositioning HIV protease inhibitors while developing more potent NO-hybridized derivatives?

Maksimovic-Ivanic, D., Fagone, P., McCubrey, J., Bendtzen, K., Mijatovic, S. & Nicoletti, F., 15 apr. 2017, I : Radiation Oncology Investigations. 140, 8, s. 1713-1726 14 s.

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Letter: can addition of an immunomodulator really reverse antibody formation and loss of response in patients treated with adalimumab?

Bendtzen, K. & Steenholdt, C., mar. 2017, I : Alimentary Pharmacology and Therapeutics. 45, 5, s. 759-760 2 s.

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Cholesterol crystals enhance TLR2- and TLR4-mediated pro-inflammatory cytokine responses of monocytes to the proatherogenic oral bacterium Porphyromonas gingivalis

Køllgaard, T., Enevold, C., Bendtzen, K., Hansen, P. R., Givskov, M., Holmstrup, P. & Nielsen, C. H., 24 feb. 2017, I : P L o S One. 12, 2, s. e0172773

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Optimizing Treatment with TNF Inhibitors in Inflammatory Bowel Disease by Monitoring Drug Levels and Antidrug Antibodies

Steenholdt, C., Bendtzen, K., Brynskov, J. & Ainsworth, M. A., 29 apr. 2016, I : Inflammatory Bowel Diseases. 22, 8, s. 1999-2015

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Circulating Cytokines and Cytokine Receptors in Infliximab Treatment Failure Due to TNF-α Independent Crohn Disease

Steenholdt, C., Coskun, M., Buhl, S., Bendtzen, K., Ainsworth, M. A., Brynskov, J. & Nielsen, O. H., apr. 2016, I : Medicine (Baltimore). 95, 16, s. e3417

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Anti-Drug Antibodies, Drug Levels, Interleukin-6 and Soluble TNF Receptors in Rheumatoid Arthritis Patients during the First 6 Months of Treatment with Adalimumab or Infliximab: A Descriptive Cohort Study

Eng, G. P., Bouchelouche, P., Bartels, E. M., Bliddal, H., Bendtzen, K. & Stoltenberg, M., 2016, I : P L o S One. 11, 9, s. e0162316

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Phthalates Are Metabolised by Primary Thyroid Cell Cultures but Have Limited Influence on Selected Thyroid Cell Functions In Vitro

Frohnert Hansen, J., Brorson, M. M., Boas, M., Frederiksen, H., Nielsen, C. H., Lindström, E. S., Hofman-Bang, J., Hartoft-Nielsen, M-L., Frisch, T., Main, K. M., Bendtzen, K., Rasmussen, Å. K. & Feldt-Rasmussen, U., 2016, I : P L o S One. 11, 3, s. e0151192 16 s.

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Time Course and Clinical Implications of Development of Antibodies Against Adalimumab in Patients With Inflammatory Bowel Disease

Steenholdt, C., Frederiksen, M. T., Bendtzen, K., Ainsworth, M. A., Thomsen, O. Ø. & Brynskov, J., 2016, I : Journal of Clinical Gastroenterology. 50, 6, s. 483-9

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Influence of phthalates on cytokine production in monocytes and macrophages: a systematic review of experimental trials

Frohnert, J., Bendtzen, K., Boas, M., Frederiksen, H., Nielsen, C. H., Rasmussen, Å. K. & Feldt-Rasmussen, U., 26 mar. 2015, I : P L o S One. 10, 3, s. e0120083

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Changes in serum trough levels of infliximab during treatment intensification but not in anti-infliximab antibody detection are associated with clinical outcomes after therapeutic failure in Crohn's disease

Steenholdt, C., Bendtzen, K., Brynskov, J., Thomsen, O. Ø., Munck, L. K., Christensen, L. A., Pedersen, G., Kjeldsen, J. & Ainsworth, M. A., mar. 2015, I : Journal of Crohn's & colitis. 9, 3, s. 238-45 8 s.

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Antibodies to infliximab and adalimumab in patients with rheumatoid arthritis in clinical remission: a cross-sectional study

Eng, G. P., Bendtzen, K., Bliddal, H., Stoltenberg, M., Szkudlarek, M., Fana, V., Lindegaard, H. M., Omerovic, E., Højgaard, P., Jensen, E. K. & Bouchelouche, P. N., 2015, I : Arthritis. 2015, s. 784825

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Immunogenicity of Anti-TNF-α Biotherapies: I. Individualized Medicine Based on Immunopharmacological Evidence

Bendtzen, K., 2015, I : Frontiers in Immunology. 6, s. 152

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Immunogenicity of Anti-TNF-α Biotherapies: II. Clinical Relevance of Methods Used for Anti-Drug Antibody Detection

Bendtzen, K., 2015, I : Frontiers in Immunology. 6, s. 109

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Individualized Therapy Is a Long-Term Cost-Effective Method Compared to Dose Intensification in Crohn's Disease Patients Failing Infliximab

Steenholdt, C., Brynskov, J., Thomsen, O. Ø., Munck, L. K., Fallingborg, J., Christensen, L. A., Pedersen, G., Kjeldsen, J., Jacobsen, B. A., Oxholm, A. S., Kjellberg, J., Bendtzen, K. & Ainsworth, M. A., 2015, I : Digestive Diseases and Sciences. 60, 9, s. 2762-70 9 s.

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Influence of phthalates on in vitro innate and adaptive immune responses

Hansen, J. F., Nielsen, C. H., Brorson, M. M., Frederiksen, H., Hartoft-Nielsen, M-L., Rasmussen, Å. K., Bendtzen, K. & Feldt-Rasmussen, U., 2015, I : P L o S One. 10, 6, s. e0131168

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Hypomethylating agent 5-aza-2'-deoxycytidine (DAC) ameliorates multiple sclerosis in mouse models

Mangano, K., Fagone, P., Bendtzen, K., Meroni, P. L., Quattrocchi, C., Mammana, S., Di Rosa, M., Malaguarnera, L., Coco, M., Magro, G., Di Marco, R. & Nicoletti, F., dec. 2014, I : Journal of Cellular Physiology. 229, 12, s. 1918-25 8 s.

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Effect of Melatonin on Human Nighttime Endotoxaemia: Randomized, Double-blinded, Cross-over Study

Alamili, M., Bendtzen, K., Lykkesfeldt, J., Rosenberg, J. & Gögenur, I., 16 nov. 2014, I : In vivo (Athens, Greece). 28, 6, s. 1057-1063 7 s.

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Antibodies against infliximab are associated with de novo development of antibodies to adalimumab and therapeutic failure in infliximab-to-adalimumab switchers with IBD

Frederiksen, M. T., Ainsworth, M. A., Brynskov, J., Thomsen, O. O., Bendtzen, K. & Steenholdt, C., okt. 2014, I : Inflammatory Bowel Diseases. 20, 10, s. 1714-21 8 s.

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Genetic polymorphisms of dsRNA ligating pattern recognition receptors TLR3, MDA5, and RIG-I. Association with systemic lupus erythematosus and clinical phenotypes

Enevold, C., Kjær, L., Nielsen, C. H., Voss, A., Jacobsen, R. S., From Hermansen, M-L., Redder, L., Oturai, A. B., Jensen, P. E., Bendtzen, K. & Jacobsen, S., okt. 2014, I : Rheumatology International. 34, 10, s. 1401-8 8 s.

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Single nucleotide polymorphisms in genes encoding toll-like receptors 7, 8 and 9 in Danish patients with systemic lupus erythematosus

Enevold, C., Nielsen, C. H., Jacobsen, R. S., From Hermansen, M-L., Molbo, D., Avlund, K., Bendtzen, K. & Jacobsen, S., sep. 2014, I : Molecular Biology Reports. 41, 9, s. 5755-63 9 s.

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Clinical implications of measuring drug and anti-drug antibodies by different assays when optimizing infliximab treatment failure in Crohn's disease: post hoc analysis of a randomized controlled trial

Steenholdt, C., Bendtzen, K., Brynskov, J., Thomsen, O. Ø. & Ainsworth, M. A., jul. 2014, I : The American journal of gastroenterology. 109, 7, s. 1055-64 10 s.

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Melatonin suppresses markers of inflammation and oxidative damage in a human daytime endotoxemia model

Alamili, M., Bendtzen, K., Lykkesfeldt, J., Rosenberg, J. & Gögenur, I., feb. 2014, I : Journal of Critical Care. 29, 1, s. 184.e9-184.e13

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A matrix of cholesterol crystals, but not cholesterol alone, primes human monocytes/macrophages for excessive endotoxin-induced production of tumor necrosis factor-alpha. Role in atherosclerotic inflammation?

Bendtzen, K., Christensen, O., Nielsen, C. H. & Holmstrup, P., 2014, I : Discovery medicine. 17, s. 309-12 4 s.

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Discontinuation of infliximab therapy in patients with Crohn's disease in sustained complete remission (the STOP IT study): protocol for a double-blind, randomised, placebo-controlled, multicentre trial

Buhl, S. S., Steenholdt, C., Brynskov, J., Thomsen, O. Ø., Bendtzen, K. & Ainsworth, M. A., 2014, I : B M J Open. 4, 12, s. e005887

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Individualised therapy is more cost-effective than dose intensification in patients with Crohn's disease who lose response to anti-TNF treatment: a randomised, controlled trial

Steenholdt, C., Brynskov, J., Thomsen, O. Ø., Munck, L. K., Fallingborg, J., Christensen, L. A., Pedersen, G., Kjeldsen, J. C. W., Jacobsen, B. A., Oxholm, A. S., Kjellberg, J., Bendtzen, K. & Ainsworth, M. A., 2014, I : Gut. 4, 63, s. 919 9 s.

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Pronounced Inflammatory Response to Endotoxaemia during Nighttime: A Randomised Cross-Over Trial

Alamili, M., Bendtzen, K., Lykkesfeldt, J., Rosenberg, J. & Gögenur, I., 2014, I : P L o S One. 9, 1, s. e87413

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Commentary: antibodies reacting with the infliximab Fab portion--something new? Authors' reply

Nielsen, C. H., Steenholdt, C., Palarasah, Y., Bendtzen, K., Teisner, A., Brynskov, J. & Teisner, B., sep. 2013, I : Alimentary Pharmacology and Therapeutics. 38, 5, s. 552-3 2 s.

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Comparison of techniques for monitoring infliximab and antibodies against infliximab in Crohn's disease

Steenholdt, C., Ainsworth, M. A., Tovey, M., Klausen, T. W., Thomsen, O. O., Brynskov, J. & Bendtzen, K., aug. 2013, I : Therapeutic Drug Monitoring. 35, 4, s. 530-8 9 s.

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Pre-existing IgG antibodies cross-reacting with the Fab region of infliximab predict efficacy and safety of infliximab therapy in inflammatory bowel disease

Steenholdt, C., Palarasah, Y., Bendtzen, K., Teisner, A., Brynskov, J., Teisner, B. & Nielsen, C. H., jun. 2013, I : Alimentary Pharmacology and Therapeutics. 37, 12, s. 1172-83 12 s.

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Personalized medicine: theranostics (therapeutics diagnostics) essential for rational use of tumor necrosis factor-alpha antagonists

Bendtzen, K., apr. 2013, I : Discovery medicine. 15, 83, s. 201-11 11 s.

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Anti-TNF-α biotherapies: perspectives for evidence-based personalized medicine

Bendtzen, K., 2012, I : Immunotherapy. 4, 11, s. 1167-79 13 s.

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Cytokine responses in infants infected with respiratory syntial virus

Breindahl, M., Rieneck, K., Nielsen, C. H., Justesen, T., Bendtzen, K. & Müller, K. G., 2012, I : Open Journal of Immunology. 2, 1, s. 40-48 8 s.

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Genetic polymorphisms of tumour necrosis factor receptor superfamily 1b and fas ligand are associated with clinical efficacy and/or acute severe infusion reactions to infliximab in Crohn's disease

Steenholdt, C., Enevold, C., Ainsworth, M. A., Brynskov, J., Thomsen, O. Ø. & Bendtzen, K., 2012, I : Alimentary Pharmacology and Therapeutics. 36, 7, s. 650-9 10 s.

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Immunoregulation by naturally occurring and disease-associated autoantibodies: binding to cytokines and their role in regulation of T-cell responses

Nielsen, C. H. & Bendtzen, K., 2012, I : Advances in Experimental Medicine and Biology. 750, s. 116-32 17 s.

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Interferon-beta increases systemic BAFF levels in multiple sclerosis without increasing autoantibody production

Hedegaard, C. J., Sellebjerg, F., Krakauer, M., Hesse, D., Bendtzen, K. & Nielsen, C. H., 1 maj 2011, I : Multiple Sclerosis. 17, 5, s. 567-77 11 s.

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Serum levels of C-reactive protein in adolescents with periodontitis

López, R., Baelum, V., Hedegaard, C. J. & Bendtzen, K., 1 apr. 2011, I : Journal of Periodontology. 82, 4, s. 543-9 7 s.

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