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Hvidovre Hospital - en del af Københavns Universitetshospital
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Mild mental stress in diabetes: changes in heart rate and subcutaneous blood-flow

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A TV-game of tennis of 20 min duration was used to study the influence of mild mental stress on subcutaneous blood-flow (SBF), blood-pressure and heart rate in nine insulin-dependent diabetics and nine healthy subjects. SBF was measured on the thigh by local clearance of xenon-133. Measurements were made before, during and after the period of stress. During stress, SBF increased significantly by 26% in the healthy subjects, while SBF remained unchanged in the diabetics. The difference between the two groups was significant (P less than 0.05). Following stress, SBF returned to pre-stress level in the healthy subjects, while a significant decrease of 33% was observed in the diabetics. The pre-stress heart rate level was higher and the stress-induced increase in heart rate was less in the diabetics compared with the healthy subjects (P less than 0.05). During the stress a slight--but insignificant--increase in blood-pressure was observed in both groups. In conclusion, we found that even mild mental strain influences SBF in both normal subjects and in diabetics. The induced alterations in the two groups are different, probably because of a slight parasympathetic dysfunction in the diabetics.
OriginalsprogEngelsk
TidsskriftClinical physiology (Oxford, England)
Vol/bind5
Udgave nummer4
Sider (fra-til)371-6
Antal sider6
ISSN0144-5979
StatusUdgivet - aug. 1985

ID: 42203796