Forskning
Udskriv Udskriv
Switch language
Hvidovre Hospital - en del af Københavns Universitetshospital
Udgivet

Magnesium sulphate treatment decreases the risk of cerebral palsy after preterm birth

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Harvard

APA

CBE

MLA

Vancouver

Author

Bibtex

@article{03d5a8d96e0e4bf1bbc3369aaec3cd2b,
title = "Magnesium sulphate treatment decreases the risk of cerebral palsy after preterm birth",
abstract = "Children born preterm have an increased risk of severe morbidity, e.g. cerebral palsy (CP), compared to children born at term. CP cannot be treated, which is why a prophylactic approach is essential, as argued in this review. Six randomised controlled trials (RCTs) have provided data on MgSO4 treatment as CP neuroprotection in preterm birth, including a new RCT from Denmark. Recently, an updated meta-analysis with trial sequential analysis detected a significant neuroprotective effect of MgSO4 treatment in preterm birth. There is now sufficient evidence, that MgSO4 treatment should be used as neuroprotection in preterm birth.",
keywords = "Cerebral Palsy/prevention & control, Child, Female, Humans, Infant, Newborn, Magnesium Sulfate/therapeutic use, Neuroprotection, Neuroprotective Agents/therapeutic use, Pregnancy, Premature Birth/prevention & control, Prenatal Care, Randomized Controlled Trials as Topic",
author = "Wolf, {Hanne Trap} and Henriksen, {Tine Brink} and Larsen, {Mads Langager} and Anja Pinborg and Hegaard, {Hanne Kristine} and Brok, {Jesper Sune} and Huusom, {Lene Drasbek}",
year = "2020",
month = nov,
day = "16",
language = "English",
volume = "182",
journal = "Ugeskrift for Laeger",
issn = "0041-5782",
publisher = "Almindelige Danske Laegeforening",
number = "47",

}

RIS

TY - JOUR

T1 - Magnesium sulphate treatment decreases the risk of cerebral palsy after preterm birth

AU - Wolf, Hanne Trap

AU - Henriksen, Tine Brink

AU - Larsen, Mads Langager

AU - Pinborg, Anja

AU - Hegaard, Hanne Kristine

AU - Brok, Jesper Sune

AU - Huusom, Lene Drasbek

PY - 2020/11/16

Y1 - 2020/11/16

N2 - Children born preterm have an increased risk of severe morbidity, e.g. cerebral palsy (CP), compared to children born at term. CP cannot be treated, which is why a prophylactic approach is essential, as argued in this review. Six randomised controlled trials (RCTs) have provided data on MgSO4 treatment as CP neuroprotection in preterm birth, including a new RCT from Denmark. Recently, an updated meta-analysis with trial sequential analysis detected a significant neuroprotective effect of MgSO4 treatment in preterm birth. There is now sufficient evidence, that MgSO4 treatment should be used as neuroprotection in preterm birth.

AB - Children born preterm have an increased risk of severe morbidity, e.g. cerebral palsy (CP), compared to children born at term. CP cannot be treated, which is why a prophylactic approach is essential, as argued in this review. Six randomised controlled trials (RCTs) have provided data on MgSO4 treatment as CP neuroprotection in preterm birth, including a new RCT from Denmark. Recently, an updated meta-analysis with trial sequential analysis detected a significant neuroprotective effect of MgSO4 treatment in preterm birth. There is now sufficient evidence, that MgSO4 treatment should be used as neuroprotection in preterm birth.

KW - Cerebral Palsy/prevention & control

KW - Child

KW - Female

KW - Humans

KW - Infant, Newborn

KW - Magnesium Sulfate/therapeutic use

KW - Neuroprotection

KW - Neuroprotective Agents/therapeutic use

KW - Pregnancy

KW - Premature Birth/prevention & control

KW - Prenatal Care

KW - Randomized Controlled Trials as Topic

M3 - Journal article

C2 - 33215580

VL - 182

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

SN - 0041-5782

IS - 47

ER -

ID: 61730534