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Hvidovre Hospital - en del af Københavns Universitetshospital
Udgivet

Magnesium sulphate treatment decreases the risk of cerebral palsy after preterm birth

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

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Vis graf over relationer

Children born preterm have an increased risk of severe morbidity, e.g. cerebral palsy (CP), compared to children born at term. CP cannot be treated, which is why a prophylactic approach is essential, as argued in this review. Six randomised controlled trials (RCTs) have provided data on MgSO4 treatment as CP neuroprotection in preterm birth, including a new RCT from Denmark. Recently, an updated meta-analysis with trial sequential analysis detected a significant neuroprotective effect of MgSO4 treatment in preterm birth. There is now sufficient evidence, that MgSO4 treatment should be used as neuroprotection in preterm birth.

OriginalsprogEngelsk
TidsskriftUgeskrift for Laeger
Vol/bind182
Udgave nummer47
ISSN0041-5782
StatusUdgivet - 16 nov. 2020

    Forskningsområder

  • Cerebral Palsy/prevention & control, Child, Female, Humans, Infant, Newborn, Magnesium Sulfate/therapeutic use, Neuroprotection, Neuroprotective Agents/therapeutic use, Pregnancy, Premature Birth/prevention & control, Prenatal Care, Randomized Controlled Trials as Topic

ID: 61730534