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Hvidovre Hospital - en del af Københavns Universitetshospital
Udgivet

Brain and immune system crosstalk: Examining the link between proinflammatory markers and glial markers measured with 1H-MRS at 7T

Publikation: Bidrag til bog/antologi/rapportKonferenceabstrakt i proceedingsForskningpeer review

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Inflammation is proposed as one of the central pillars driving ageing. This study was the first to link peripheral inflammation to brain metabolite differences during normal ageing and to associate this to visuo-spatial working memory performance. Our data shows how peripheral inflammatory markers were associated with performance on visuo-spatial working memory and glial metabolic markers in ACC, Hippocampus, and Thalamus. The findings highlight the role of glial cells as part of the neurobiological link between peripheral inflammation and cognitive performance during ageing.
OriginalsprogEngelsk
TitelProceedings of the 2020 ISMRM & SMRT Virtual Conference & Exhibition
Antal sider1
ForlagThe International Society for Magnetic Resonance in Medicine
Publikationsdato2020
Sider1-1
Artikelnummer1853
StatusUdgivet - 2020

ID: 62050590