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Hvidovre Hospital - en del af Københavns Universitetshospital
Udgivet

Antimicrobial resistance in the Bacteroides fragilis group in faecal microbiota from healthy Danish children

Publikation: Bidrag til tidsskriftTidsskriftartikelpeer review

  • Thomas Vognbjerg Sydenham
  • Betina Hebbelstrup Jensen
  • Andreas Munk Petersen
  • Karen Angeliki Krogfelt
  • Ulrik Stenz Justesen
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The Bacteroides fragilis group constitute a significant portion of the human gut microbiota and comprise a major proportion of anaerobic bacteria isolated in human infections. We established a baseline of antimicrobial susceptibility rates in the B. fragilis group in the intestinal tract of relatively antibiotic-naive healthy Danish children. From 174 faecal samples collected from children attending day care, 359 non-duplicate isolates were screened for antimicrobial susceptibility. Of these, 0.0%, 1.9%, 5.0% and 21.2% of isolates were intermediate-susceptible or resistant to metronidazole, meropenem, piperacillin/tazobactam and clindamycin, respectively. Eighteen additional studies reporting susceptibility rates in the B. fragilis group bacteria were identified by conducting a literature search. Heterogeneity among results from studies of B. fragilis group antimicrobial susceptibility rates in faecal microbiota exists.

OriginalsprogEngelsk
TidsskriftInternational Journal of Antimicrobial Agents
Vol/bind49
Udgave nummer5
Sider (fra-til)573-578
ISSN0924-8579
DOI
StatusUdgivet - 1 maj 2017

ID: 50179707