White matter microstructural changes of thalamocortical networks in photosensitivity and idiopathic generalized epilepsy

Sergiu Groppa; Friederike Moeller; Hartwig Siebner; Stephan Wolff; Christian Riedel; Günther Deuschl; Ulrich Stephani; Michael Siniatchkin

doi:10.1111/j.1528-1167.2012.03414.x

White matter microstructural changes of thalamocortical networks in photosensitivity and idiopathic generalized epilepsy

Sergiu Groppa, Friederike Moeller, Hartwig Siebner, Stephan Wolff, Christian Riedel, Günther Deuschl, Ulrich Stephani, Michael Siniatchkin

Danish Research Centre for Magnetic Resonance

30 Citations (Scopus)

Abstract

Photosensitivity or photoparoxysmal response (PPR) is an electroencephalography trait that is highly associated with idiopathic generalized epilepsies (IGEs) and characterized by changes in cortical excitability in response to photic stimulation. Studying functional and structural changes of PPR might provide important insights into the pathogenesis of IGE. Recent studies revealed a functional network consisting of occipital, parietal, and precentral areas that might be implicated in PPR. Herein, we investigate the microstructural changes associated with PPR.

Original language	English
Journal	Epilepsia-lehti
Volume	53
Issue number	4
Pages (from-to)	668-76
Number of pages	9
ISSN	0780-0150
DOIs	https://doi.org/10.1111/j.1528-1167.2012.03414.x
Publication status	Published - 2012

Keywords

Adolescent
Brain Mapping
Cerebral Cortex
Diffusion Tensor Imaging
Electroencephalography
Epilepsy, Generalized
Female
Humans
Image Processing, Computer-Assisted
Male
Neural Pathways
Photic Stimulation
Thalamus
Young Adult

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10.1111/j.1528-1167.2012.03414.x

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title = "White matter microstructural changes of thalamocortical networks in photosensitivity and idiopathic generalized epilepsy",

abstract = "Photosensitivity or photoparoxysmal response (PPR) is an electroencephalography trait that is highly associated with idiopathic generalized epilepsies (IGEs) and characterized by changes in cortical excitability in response to photic stimulation. Studying functional and structural changes of PPR might provide important insights into the pathogenesis of IGE. Recent studies revealed a functional network consisting of occipital, parietal, and precentral areas that might be implicated in PPR. Herein, we investigate the microstructural changes associated with PPR.",

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AU - Groppa, Sergiu

AU - Moeller, Friederike

AU - Siebner, Hartwig

AU - Wolff, Stephan

AU - Riedel, Christian

AU - Deuschl, Günther

AU - Stephani, Ulrich

AU - Siniatchkin, Michael

PY - 2012

Y1 - 2012

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AB - Photosensitivity or photoparoxysmal response (PPR) is an electroencephalography trait that is highly associated with idiopathic generalized epilepsies (IGEs) and characterized by changes in cortical excitability in response to photic stimulation. Studying functional and structural changes of PPR might provide important insights into the pathogenesis of IGE. Recent studies revealed a functional network consisting of occipital, parietal, and precentral areas that might be implicated in PPR. Herein, we investigate the microstructural changes associated with PPR.

KW - Adolescent

KW - Brain Mapping

KW - Cerebral Cortex

KW - Diffusion Tensor Imaging

KW - Electroencephalography

KW - Epilepsy, Generalized

KW - Female

KW - Humans

KW - Image Processing, Computer-Assisted

KW - Male

KW - Neural Pathways

KW - Photic Stimulation

KW - Thalamus

KW - Young Adult

KW - Generalized epilepsy;Photosensitivity;Photoparoxysmal response;Diffusion tensor imaging

UR - https://www.scopus.com/pages/publications/84859424088

U2 - 10.1111/j.1528-1167.2012.03414.x

DO - 10.1111/j.1528-1167.2012.03414.x

M3 - Journal article

C2 - 22360784

SN - 0780-0150

VL - 53

SP - 668

EP - 676

JO - Epilepsia-lehti

JF - Epilepsia-lehti

IS - 4

ER -

White matter microstructural changes of thalamocortical networks in photosensitivity and idiopathic generalized epilepsy

Abstract

Keywords

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