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What can be learned from the history of recurrence in migraine? A comment

    7 Citations (Scopus)

    Abstract

    Recurrence was first recognised as a clinical problem in 1989 with the advent of sumatriptan. The history of recurrence in early sumatriptan randomised clinical trials is described. Recurrence has been ascribed to patient-dependent factors but experience with ergot alkaloids suggested that recurrence can also be treatment-dependent. Possible mechanisms for recurrence are discussed.
    Original languageEnglish
    JournalJournal of Headache and Pain
    Volume10
    Issue number5
    Pages (from-to)311-5
    Number of pages4
    ISSN1129-2369
    DOIs
    Publication statusPublished - 2009

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