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Vitamin D and Calcium Milk Fortification in Pregnant Women with Periodontitis: A Feasibility Trial

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Rodrigues Amorim Adegboye, A, Dias Santana, D, Cocate, PG, Benaim, C, Teixeira Dos Santos, PP, Heitmann, BL, da Veiga Soares Carvalho, MC, Schlüssel, MM, Trindade de Castro, MB & Kac, G 2020, 'Vitamin D and Calcium Milk Fortification in Pregnant Women with Periodontitis: A Feasibility Trial', International Journal of Environmental Research and Public Health, vol. 17, no. 21. https://doi.org/10.3390/ijerph17218023

APA

Rodrigues Amorim Adegboye, A., Dias Santana, D., Cocate, P. G., Benaim, C., Teixeira Dos Santos, P. P., Heitmann, B. L., da Veiga Soares Carvalho, M. C., Schlüssel, M. M., Trindade de Castro, M. B., & Kac, G. (2020). Vitamin D and Calcium Milk Fortification in Pregnant Women with Periodontitis: A Feasibility Trial. International Journal of Environmental Research and Public Health, 17(21). https://doi.org/10.3390/ijerph17218023

CBE

Rodrigues Amorim Adegboye A, Dias Santana D, Cocate PG, Benaim C, Teixeira Dos Santos PP, Heitmann BL, da Veiga Soares Carvalho MC, Schlüssel MM, Trindade de Castro MB, Kac G. 2020. Vitamin D and Calcium Milk Fortification in Pregnant Women with Periodontitis: A Feasibility Trial. International Journal of Environmental Research and Public Health. 17(21). https://doi.org/10.3390/ijerph17218023

MLA

Vancouver

Author

Rodrigues Amorim Adegboye, Amanda ; Dias Santana, Danilo ; Cocate, Paula Guedes ; Benaim, Camila ; Teixeira Dos Santos, Pedro Paulo ; Heitmann, Berit Lilienthal ; da Veiga Soares Carvalho, Maria Cláudia ; Schlüssel, Michael Maia ; Trindade de Castro, Maria Beatriz ; Kac, Gilberto. / Vitamin D and Calcium Milk Fortification in Pregnant Women with Periodontitis : A Feasibility Trial. In: International Journal of Environmental Research and Public Health. 2020 ; Vol. 17, No. 21.

Bibtex

@article{76b738e4b23b47faa9988479dd489ec8,
title = "Vitamin D and Calcium Milk Fortification in Pregnant Women with Periodontitis: A Feasibility Trial",
abstract = "This study aims to assess the acceptability, adherence, and retention of a feasibility trial on milk fortification with calcium and vitamin D (Ca+VitD) and periodontal therapy (PT) among low income Brazilian pregnant women with periodontitis (IMPROVE trial). This 2 × 2 factorial feasibility trial used a mixed-methods evaluation. In total, 69 pregnant women were randomly allocated to four groups: 1. fortified sachet with Ca+VitD and milk plus early PT (throughout gestation); 2. placebo and milk plus early PT; 3. fortified sachet with Ca+VitD and milk plus late PT after childbirth; 4. placebo and milk plus late PT. Data were collected via questionnaires, field notes, participant flow logs, treatment diary, and focal group discussions. Quantitative and qualitative data were analysed using appropriate descriptive statistics and content analysis, respectively. Eligibility rate (12%) was below the target of 15%, but participation (76.1%) and recruitment rate (2 women/week) exceeded the targets. Retention rate (78.6%) was slightly below the target (80%). Adherence to the PT was significantly higher in the early treatment groups (98.8%) compared to the late treatment groups (29%). All women accepted the random allocation, and baseline groups were balanced. There was no report of adverse events. This multi-component intervention is acceptable, well-tolerated, and feasible among low-risk pregnant women in Brazil.",
keywords = "Animals, Brazil, Calcium Carbonate, Feasibility Studies, Female, Food, Fortified, Humans, Milk, Periodontitis/therapy, Pregnancy, Pregnancy Complications/therapy, Pregnant Women, Vitamin D/therapeutic use, Vitamins/therapeutic use, adherence, pregnancy, attrition rate, periodontal therapy, acceptability, feasibility, milk fortification",
author = "{Rodrigues Amorim Adegboye}, Amanda and {Dias Santana}, Danilo and Cocate, {Paula Guedes} and Camila Benaim and {Teixeira Dos Santos}, {Pedro Paulo} and Heitmann, {Berit Lilienthal} and {da Veiga Soares Carvalho}, {Maria Cl{\'a}udia} and Schl{\"u}ssel, {Michael Maia} and {Trindade de Castro}, {Maria Beatriz} and Gilberto Kac",
year = "2020",
month = oct,
day = "30",
doi = "10.3390/ijerph17218023",
language = "English",
volume = "17",
journal = "International Journal of Environmental Research and Public Health",
issn = "1661-7827",
publisher = "MDPI AG",
number = "21",

}

RIS

TY - JOUR

T1 - Vitamin D and Calcium Milk Fortification in Pregnant Women with Periodontitis

T2 - A Feasibility Trial

AU - Rodrigues Amorim Adegboye, Amanda

AU - Dias Santana, Danilo

AU - Cocate, Paula Guedes

AU - Benaim, Camila

AU - Teixeira Dos Santos, Pedro Paulo

AU - Heitmann, Berit Lilienthal

AU - da Veiga Soares Carvalho, Maria Cláudia

AU - Schlüssel, Michael Maia

AU - Trindade de Castro, Maria Beatriz

AU - Kac, Gilberto

PY - 2020/10/30

Y1 - 2020/10/30

N2 - This study aims to assess the acceptability, adherence, and retention of a feasibility trial on milk fortification with calcium and vitamin D (Ca+VitD) and periodontal therapy (PT) among low income Brazilian pregnant women with periodontitis (IMPROVE trial). This 2 × 2 factorial feasibility trial used a mixed-methods evaluation. In total, 69 pregnant women were randomly allocated to four groups: 1. fortified sachet with Ca+VitD and milk plus early PT (throughout gestation); 2. placebo and milk plus early PT; 3. fortified sachet with Ca+VitD and milk plus late PT after childbirth; 4. placebo and milk plus late PT. Data were collected via questionnaires, field notes, participant flow logs, treatment diary, and focal group discussions. Quantitative and qualitative data were analysed using appropriate descriptive statistics and content analysis, respectively. Eligibility rate (12%) was below the target of 15%, but participation (76.1%) and recruitment rate (2 women/week) exceeded the targets. Retention rate (78.6%) was slightly below the target (80%). Adherence to the PT was significantly higher in the early treatment groups (98.8%) compared to the late treatment groups (29%). All women accepted the random allocation, and baseline groups were balanced. There was no report of adverse events. This multi-component intervention is acceptable, well-tolerated, and feasible among low-risk pregnant women in Brazil.

AB - This study aims to assess the acceptability, adherence, and retention of a feasibility trial on milk fortification with calcium and vitamin D (Ca+VitD) and periodontal therapy (PT) among low income Brazilian pregnant women with periodontitis (IMPROVE trial). This 2 × 2 factorial feasibility trial used a mixed-methods evaluation. In total, 69 pregnant women were randomly allocated to four groups: 1. fortified sachet with Ca+VitD and milk plus early PT (throughout gestation); 2. placebo and milk plus early PT; 3. fortified sachet with Ca+VitD and milk plus late PT after childbirth; 4. placebo and milk plus late PT. Data were collected via questionnaires, field notes, participant flow logs, treatment diary, and focal group discussions. Quantitative and qualitative data were analysed using appropriate descriptive statistics and content analysis, respectively. Eligibility rate (12%) was below the target of 15%, but participation (76.1%) and recruitment rate (2 women/week) exceeded the targets. Retention rate (78.6%) was slightly below the target (80%). Adherence to the PT was significantly higher in the early treatment groups (98.8%) compared to the late treatment groups (29%). All women accepted the random allocation, and baseline groups were balanced. There was no report of adverse events. This multi-component intervention is acceptable, well-tolerated, and feasible among low-risk pregnant women in Brazil.

KW - Animals

KW - Brazil

KW - Calcium Carbonate

KW - Feasibility Studies

KW - Female

KW - Food, Fortified

KW - Humans

KW - Milk

KW - Periodontitis/therapy

KW - Pregnancy

KW - Pregnancy Complications/therapy

KW - Pregnant Women

KW - Vitamin D/therapeutic use

KW - Vitamins/therapeutic use

KW - adherence

KW - pregnancy

KW - attrition rate

KW - periodontal therapy

KW - acceptability

KW - feasibility

KW - milk fortification

U2 - 10.3390/ijerph17218023

DO - 10.3390/ijerph17218023

M3 - Journal article

C2 - 33143369

VL - 17

JO - International Journal of Environmental Research and Public Health

JF - International Journal of Environmental Research and Public Health

SN - 1661-7827

IS - 21

ER -

ID: 61195167