Ventrikelcancer er den hyppigste Epstein-Barr-virus-associerede cancerform

Trine Boysen; Jeppe Friborg

Ventrikelcancer er den hyppigste Epstein-Barr-virus-associerede cancerform

Translated title of the contribution: Gastric carcinoma is the most frequent Epstein-Barr virus-associated malignancy

Trine Boysen
, Jeppe Friborg

1 Citation (Scopus)

Abstract

Epstein-Barr virus (EBV) is associated with 8% of gastric carcinomas (GC) worldwide, being the most frequent EBV-associated malignancy with 80,000 new cases per year. The association is based on the presence of clonal EBV products in gastric tumour cells, and elevated EBV antibodies in pre-diagnostic sera. EBV-associated GC are twice as common in males and often associated to cancer in the cardia-region. Gastric surgery increases the risk significantly. Until now, no clear interaction between Helicobacter pylori, the single most important risk factor for GC, and EBV has been established.

Translated title of the contribution	Gastric carcinoma is the most frequent Epstein-Barr virus-associated malignancy
Original language	Danish
Journal	Ugeskrift for Laeger
Volume	175
Issue number	47A
ISSN	0041-5782
Publication status	Published - 18 Nov 2013
Externally published	Yes

Cite this

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title = "Ventrikelcancer er den hyppigste Epstein-Barr-virus-associerede cancerform",

abstract = "Epstein-Barr virus (EBV) is associated with 8\% of gastric carcinomas (GC) worldwide, being the most frequent EBV-associated malignancy with 80,000 new cases per year. The association is based on the presence of clonal EBV products in gastric tumour cells, and elevated EBV antibodies in pre-diagnostic sera. EBV-associated GC are twice as common in males and often associated to cancer in the cardia-region. Gastric surgery increases the risk significantly. Until now, no clear interaction between Helicobacter pylori, the single most important risk factor for GC, and EBV has been established.",

keywords = "Carcinoma/epidemiology, Epstein-Barr Virus Infections/complications, Herpesvirus 4, Human/genetics, Humans, Male, Stomach Neoplasms/epidemiology",

author = "Trine Boysen and Jeppe Friborg",

year = "2013",

month = nov,

day = "18",

language = "Dansk",

volume = "175",

journal = "Ugeskrift for Laeger",

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publisher = "Almindelige Danske L{\ae}geforening",

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TY - JOUR

T1 - Ventrikelcancer er den hyppigste Epstein-Barr-virus-associerede cancerform

AU - Boysen, Trine

AU - Friborg, Jeppe

PY - 2013/11/18

Y1 - 2013/11/18

N2 - Epstein-Barr virus (EBV) is associated with 8% of gastric carcinomas (GC) worldwide, being the most frequent EBV-associated malignancy with 80,000 new cases per year. The association is based on the presence of clonal EBV products in gastric tumour cells, and elevated EBV antibodies in pre-diagnostic sera. EBV-associated GC are twice as common in males and often associated to cancer in the cardia-region. Gastric surgery increases the risk significantly. Until now, no clear interaction between Helicobacter pylori, the single most important risk factor for GC, and EBV has been established.

AB - Epstein-Barr virus (EBV) is associated with 8% of gastric carcinomas (GC) worldwide, being the most frequent EBV-associated malignancy with 80,000 new cases per year. The association is based on the presence of clonal EBV products in gastric tumour cells, and elevated EBV antibodies in pre-diagnostic sera. EBV-associated GC are twice as common in males and often associated to cancer in the cardia-region. Gastric surgery increases the risk significantly. Until now, no clear interaction between Helicobacter pylori, the single most important risk factor for GC, and EBV has been established.

KW - Carcinoma/epidemiology

KW - Epstein-Barr Virus Infections/complications

KW - Herpesvirus 4, Human/genetics

KW - Humans

KW - Male

KW - Stomach Neoplasms/epidemiology

UR - https://www.scopus.com/pages/publications/84990303153

M3 - Review

C2 - 25353091

SN - 0041-5782

VL - 175

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

IS - 47A

ER -

Ventrikelcancer er den hyppigste Epstein-Barr-virus-associerede cancerform

Abstract

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