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Vascularized fibula grafts for reconstruction of bone defects after resection of bone sarcomas

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  1. Patient and Tumour Characteristics of Adult Head and Neck Soft Tissue Sarcomas: A Systematic Review and Meta-Analysis

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  2. Use of Healthcare Services Two Years before Diagnosis in Danish Sarcoma Patients, 2000-2013

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  3. A Phase I/II Clinical Trial of Belinostat (PXD101) in Combination with Doxorubicin in Patients with Soft Tissue Sarcomas

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  4. Metastatic pattern, local relapse, and survival of patients with myxoid liposarcoma: a retrospective study of 45 patients

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  5. Delays in the management of retroperitoneal sarcomas

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  1. Collagen Growth Pattern in Human Articular Cartilage of the Knee

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  2. Clinical outcome after surgery on schwannomas in the extremities

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  3. Preoperative BMD does not influence femoral stem subsidence of uncemented THA when the femoral T-score is > -2.5

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We evaluated the results of limb-sparing surgery and reconstruction of bone defects with vascularized fibula grafts in 8 consecutive patients (mean age at operation 13.6 years (range 4.1-24.2 years), female/male = 6/2) with bone sarcomas (BS) (osteosarcoma/Ewing's sarcoma/chondrosarcoma= 4/3/1) operated on form 2000 to 2006. The bone defects reconstructed were proximal femoral diaphysis and epiphysis (n = 2), humeral diaphysis (n = 2), humeral proximal diaphysis and epiphysis (n = 1), femoral diaphysis (n = 1), ulnar diaphysis (n = 1), and tibial diaphysis (n = 1). One patient with Ewing's sarcoma had an early hip disarticulation, developed multiple metastases, and died 9 months after the operation. The remaining patients (n = 7) are all alive 50 months (range 26-75 months) after surgery. During the follow-up the following major complications were seen: 1-2 fractures (n = 4), pseudarthrosis (n = 2), and hip dislocation (n = 1). Limb-sparing surgery with reconstruction of bone defects using vascularized fibular grafts in BS cases is feasible with acceptable clinical results, but fractures should be expected in many patients.
Original languageEnglish
JournalSarcoma
Volume2010
Pages (from-to)524721
ISSN1357-714X
DOIs
Publication statusPublished - 1 Jan 2010

ID: 31068165