Variants of DENND1B associated with asthma in children

Patrick M A Sleiman; James Flory; Marcin Imielinski; Jonathan P Bradfield; Kiran Annaiah; Saffron A G Willis-Owen; Kai Wang; Nicholas M Rafaels; Sven Michel; Klaus Bønnelykke; Haitao Zhang; Cecilia E Kim; Edward C Frackelton; Joseph T Glessner; Cuiping Hou; F George Otieno; Erin Santa; Kelly Thomas; Ryan M Smith; Wendy R Glaberson; Maria Garris; Rosetta M Chiavacci; Terri H Beaty; Ingo Ruczinski; Jordan M Orange; Julian Allen; Jonathan M Spergel; Robert Grundmeier; Rasika A Mathias; Jason D Christie; Erika von Mutius; William O C Cookson; Michael Kabesch; Miriam F Moffatt; Michael M Grunstein; Kathleen C Barnes; Marcella Devoto; Mark Magnusson; Hongzhe Li; Struan F A Grant; Hans Bisgaard; Hakon Hakonarson

doi:10.1056/NEJMoa0901867

Variants of DENND1B associated with asthma in children

Patrick M A Sleiman, James Flory, Marcin Imielinski, Jonathan P Bradfield, Kiran Annaiah, Saffron A G Willis-Owen, Kai Wang, Nicholas M Rafaels, Sven Michel, Klaus Bønnelykke, Haitao Zhang, Cecilia E Kim, Edward C Frackelton, Joseph T Glessner, Cuiping Hou, F George Otieno, Erin Santa, Kelly Thomas, Ryan M Smith, Wendy R GlabersonMaria Garris, Rosetta M Chiavacci, Terri H Beaty, Ingo Ruczinski, Jordan M Orange, Julian Allen, Jonathan M Spergel, Robert Grundmeier, Rasika A Mathias, Jason D Christie, Erika von Mutius, William O C Cookson, Michael Kabesch, Miriam F Moffatt, Michael M Grunstein, Kathleen C Barnes, Marcella Devoto, Mark Magnusson, Hongzhe Li, Struan F A Grant, Hans Bisgaard, Hakon Hakonarson

Dermatology and Allergy

277 Citations (Scopus)

Abstract

Asthma is a complex disease that has genetic and environmental causes. The genetic factors associated with susceptibility to asthma remain largely unknown.

Original language	English
Journal	New England Journal of Medicine
Volume	362
Issue number	1
Pages (from-to)	36-44
Number of pages	9
ISSN	0028-4793
DOIs	https://doi.org/10.1056/NEJMoa0901867
Publication status	Published - 7 Jan 2010

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Sleiman, P. M. A., Flory, J., Imielinski, M., Bradfield, J. P., Annaiah, K., Willis-Owen, S. A. G., Wang, K., Rafaels, N. M., Michel, S., Bønnelykke, K., Zhang, H., Kim, C. E., Frackelton, E. C., Glessner, J. T., Hou, C., Otieno, F. G., Santa, E., Thomas, K., Smith, R. M., ... Hakonarson, H. (2010). Variants of DENND1B associated with asthma in children. New England Journal of Medicine, 362(1), 36-44. https://doi.org/10.1056/NEJMoa0901867

Sleiman, PMA, Flory, J, Imielinski, M, Bradfield, JP, Annaiah, K, Willis-Owen, SAG, Wang, K, Rafaels, NM, Michel, S, Bønnelykke, K, Zhang, H, Kim, CE, Frackelton, EC, Glessner, JT, Hou, C, Otieno, FG, Santa, E, Thomas, K, Smith, RM, Glaberson, WR, Garris, M, Chiavacci, RM, Beaty, TH, Ruczinski, I, Orange, JM, Allen, J, Spergel, JM, Grundmeier, R, Mathias, RA, Christie, JD, von Mutius, E, Cookson, WOC, Kabesch, M, Moffatt, MF, Grunstein, MM, Barnes, KC, Devoto, M, Magnusson, M, Li, H, Grant, SFA, Bisgaard, H & Hakonarson, H 2010, 'Variants of DENND1B associated with asthma in children', New England Journal of Medicine, vol. 362, no. 1, pp. 36-44. https://doi.org/10.1056/NEJMoa0901867

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title = "Variants of DENND1B associated with asthma in children",

abstract = "Asthma is a complex disease that has genetic and environmental causes. The genetic factors associated with susceptibility to asthma remain largely unknown.",

author = "Sleiman, \{Patrick M A\} and James Flory and Marcin Imielinski and Bradfield, \{Jonathan P\} and Kiran Annaiah and Willis-Owen, \{Saffron A G\} and Kai Wang and Rafaels, \{Nicholas M\} and Sven Michel and Klaus B{\o}nnelykke and Haitao Zhang and Kim, \{Cecilia E\} and Frackelton, \{Edward C\} and Glessner, \{Joseph T\} and Cuiping Hou and Otieno, \{F George\} and Erin Santa and Kelly Thomas and Smith, \{Ryan M\} and Glaberson, \{Wendy R\} and Maria Garris and Chiavacci, \{Rosetta M\} and Beaty, \{Terri H\} and Ingo Ruczinski and Orange, \{Jordan M\} and Julian Allen and Spergel, \{Jonathan M\} and Robert Grundmeier and Mathias, \{Rasika A\} and Christie, \{Jason D\} and \{von Mutius\}, Erika and Cookson, \{William O C\} and Michael Kabesch and Moffatt, \{Miriam F\} and Grunstein, \{Michael M\} and Barnes, \{Kathleen C\} and Marcella Devoto and Mark Magnusson and Hongzhe Li and Grant, \{Struan F A\} and Hans Bisgaard and Hakon Hakonarson",

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AU - Allen, Julian

AU - Spergel, Jonathan M

AU - Grundmeier, Robert

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AU - Kabesch, Michael

AU - Moffatt, Miriam F

AU - Grunstein, Michael M

AU - Barnes, Kathleen C

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AU - Li, Hongzhe

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Variants of DENND1B associated with asthma in children

Abstract

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