Research
Print page Print page
Switch language
The Capital Region of Denmark - a part of Copenhagen University Hospital
Published

Validation of the Danish SARC-F in Hospitalized, Geriatric Medical Patients

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

APA

CBE

MLA

Vancouver

Author

Bibtex

@article{ed72b61f8c5440e5a21f2d427b71b936,
title = "Validation of the Danish SARC-F in Hospitalized, Geriatric Medical Patients",
abstract = "OBJECTIVES: Validation of the Danish version of the SARC-F (Strength, Assistance in walking, Rise from a chair, Climb stairs, and Falls) for hospitalized geriatric medical patients, compared against the original EWGSOP (European Working Group on Sarcopenia in Older People) and revised EWGSOP2 definition for sarcopenia. Additionally, investigation of the ability of SARC-F to individually identify low strength/function and muscle mass.DESIGN: Cross-sectional analysis of data from an RCT.SETTING: Hospital, Medical Department.PARTICIPANTS: 122 geriatric medical patients (65.6% women) ≥ 70 years of age with mixed medical conditions.MEASUREMENTS: SARC-F screening, diagnostic assessment of sarcopenia (hand-grip strength, muscle mass measured by dual-frequency bio-impedance analysis, and 4-m usual gait speed).RESULTS: The prevalence of risk of sarcopenia (SARC-F ≥ 4) was 48.3%, while it was diagnosed in 65.8% and 21.7%, with EWGSOP and EWGSOP2, respectively. The sensitivity, specificity, positive predictive value, negative predictive value according to EWGSOP were 50.0 %, 53.7 %, 67.2% and 36.1%, while they were 53.8 %, 53.2 %, 24.1% and 80.6%, according to EWGSOP2 (all participants). The ability of SARC-F to predict reduced strength, function, and muscle mass was modest. There was a significant negative linear, yet weak, relationship between total SARC-F score and hand-grip strength (R2=0.033) and 4-m gait speed (R2=0.111), but not muscle mass (R2=0.004).CONCLUSION: SARC-F does not seem to be a suitable screening tool for identifying and excluding non-sarcopenic geriatric patients. Furthermore, the SARC-F score was more strongly correlated with reduced muscle strength and physical function than with low muscle mass.",
keywords = "Sarcopenia, acutely ill, older adults, physical function, screening",
author = "J Gade and Beck, {Anne Marie} and Finn R{\o}nholt and Andersen, {H E} and T Munk and Anders Vinther",
year = "2020",
month = dec,
doi = "10.1007/s12603-020-1453-x",
language = "English",
volume = "24",
pages = "1120--1127",
journal = "Journal of Nutrition, Health and Aging",
issn = "1279-7707",
publisher = "SERDI Publisher",
number = "10",

}

RIS

TY - JOUR

T1 - Validation of the Danish SARC-F in Hospitalized, Geriatric Medical Patients

AU - Gade, J

AU - Beck, Anne Marie

AU - Rønholt, Finn

AU - Andersen, H E

AU - Munk, T

AU - Vinther, Anders

PY - 2020/12

Y1 - 2020/12

N2 - OBJECTIVES: Validation of the Danish version of the SARC-F (Strength, Assistance in walking, Rise from a chair, Climb stairs, and Falls) for hospitalized geriatric medical patients, compared against the original EWGSOP (European Working Group on Sarcopenia in Older People) and revised EWGSOP2 definition for sarcopenia. Additionally, investigation of the ability of SARC-F to individually identify low strength/function and muscle mass.DESIGN: Cross-sectional analysis of data from an RCT.SETTING: Hospital, Medical Department.PARTICIPANTS: 122 geriatric medical patients (65.6% women) ≥ 70 years of age with mixed medical conditions.MEASUREMENTS: SARC-F screening, diagnostic assessment of sarcopenia (hand-grip strength, muscle mass measured by dual-frequency bio-impedance analysis, and 4-m usual gait speed).RESULTS: The prevalence of risk of sarcopenia (SARC-F ≥ 4) was 48.3%, while it was diagnosed in 65.8% and 21.7%, with EWGSOP and EWGSOP2, respectively. The sensitivity, specificity, positive predictive value, negative predictive value according to EWGSOP were 50.0 %, 53.7 %, 67.2% and 36.1%, while they were 53.8 %, 53.2 %, 24.1% and 80.6%, according to EWGSOP2 (all participants). The ability of SARC-F to predict reduced strength, function, and muscle mass was modest. There was a significant negative linear, yet weak, relationship between total SARC-F score and hand-grip strength (R2=0.033) and 4-m gait speed (R2=0.111), but not muscle mass (R2=0.004).CONCLUSION: SARC-F does not seem to be a suitable screening tool for identifying and excluding non-sarcopenic geriatric patients. Furthermore, the SARC-F score was more strongly correlated with reduced muscle strength and physical function than with low muscle mass.

AB - OBJECTIVES: Validation of the Danish version of the SARC-F (Strength, Assistance in walking, Rise from a chair, Climb stairs, and Falls) for hospitalized geriatric medical patients, compared against the original EWGSOP (European Working Group on Sarcopenia in Older People) and revised EWGSOP2 definition for sarcopenia. Additionally, investigation of the ability of SARC-F to individually identify low strength/function and muscle mass.DESIGN: Cross-sectional analysis of data from an RCT.SETTING: Hospital, Medical Department.PARTICIPANTS: 122 geriatric medical patients (65.6% women) ≥ 70 years of age with mixed medical conditions.MEASUREMENTS: SARC-F screening, diagnostic assessment of sarcopenia (hand-grip strength, muscle mass measured by dual-frequency bio-impedance analysis, and 4-m usual gait speed).RESULTS: The prevalence of risk of sarcopenia (SARC-F ≥ 4) was 48.3%, while it was diagnosed in 65.8% and 21.7%, with EWGSOP and EWGSOP2, respectively. The sensitivity, specificity, positive predictive value, negative predictive value according to EWGSOP were 50.0 %, 53.7 %, 67.2% and 36.1%, while they were 53.8 %, 53.2 %, 24.1% and 80.6%, according to EWGSOP2 (all participants). The ability of SARC-F to predict reduced strength, function, and muscle mass was modest. There was a significant negative linear, yet weak, relationship between total SARC-F score and hand-grip strength (R2=0.033) and 4-m gait speed (R2=0.111), but not muscle mass (R2=0.004).CONCLUSION: SARC-F does not seem to be a suitable screening tool for identifying and excluding non-sarcopenic geriatric patients. Furthermore, the SARC-F score was more strongly correlated with reduced muscle strength and physical function than with low muscle mass.

KW - Sarcopenia

KW - acutely ill

KW - older adults

KW - physical function

KW - screening

UR - http://www.scopus.com/inward/record.url?scp=85089870025&partnerID=8YFLogxK

U2 - 10.1007/s12603-020-1453-x

DO - 10.1007/s12603-020-1453-x

M3 - Journal article

C2 - 33244571

VL - 24

SP - 1120

EP - 1127

JO - Journal of Nutrition, Health and Aging

JF - Journal of Nutrition, Health and Aging

SN - 1279-7707

IS - 10

ER -

ID: 61557493