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Validation of the Brief Assessment of Impaired Cognition and the Brief Assessment of Impaired Cognition Questionnaire for identification of mild cognitive impairment in a memory clinic setting

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@article{4c43c5d933a540d6ad8cab3cf45e5f9e,
title = "Validation of the Brief Assessment of Impaired Cognition and the Brief Assessment of Impaired Cognition Questionnaire for identification of mild cognitive impairment in a memory clinic setting",
abstract = "OBJECTIVES: The aim of this study was to validate the Brief Assessment of Impaired Cognition (BASIC) and the Brief Assessment of Impaired Cognition Questionnaire (BASIC-Q) for identification of mild cognitive impairment (MCI) in a memory clinic setting.METHODS: A total of 163 sociodemographically matched patients (MCI, n = 42, and dementia, n = 121) and 83 control participants were included in the study. Two instruments were validated: (a) BASIC, including the components self-report, informant report, and two brief cognitive tests, and (b) BASIC-Q, including the components self-report, informant report, and orientation. BASIC can be administered in 5 minutes and BASIC-Q in less than 5 minutes.RESULTS: A high discriminative validity for MCI vs control participants was found for both BASIC (sensitivity 0.86, specificity 0.89) and BASIC-Q (sensitivity 0.88, specificity 0.88). In comparison, the MMSE had low sensitivity (0.61) and moderate specificity (0.72). All components of BASIC and BASIC-Q contributed significantly to differentiate MCI from control participants. The components of BASIC and BASIC-Q also contributed significantly to differentiate MCI from dementia, except for self-report, which was identical in the two groups.CONCLUSIONS: Both BASIC and BASIC-Q are brief, valid, and effective instruments for identification of patients with possible MCI in a memory clinic setting. Further cross-validation of the instruments in a general practice or primary care setting is needed.",
keywords = "BASIC, BASIC-Q, cognitive assessment, cognitive screening, dementia, diagnostic accuracy, discriminative validity, mild cognitive impairment, predictive validity",
author = "Kasper J{\o}rgensen and Nielsen, {Thomas R} and Ann Nielsen and Waldorff, {Frans B} and Gunhild Waldemar",
note = "{\textcopyright} 2020 The Authors. International Journal of Geriatric Psychiatry published by John Wiley & Sons Ltd.",
year = "2020",
month = aug,
doi = "10.1002/gps.5312",
language = "English",
volume = "35",
pages = "907--915",
journal = "International Journal of Geriatric Psychiatry",
issn = "0885-6230",
publisher = "John/Wiley & Sons Ltd",
number = "8",

}

RIS

TY - JOUR

T1 - Validation of the Brief Assessment of Impaired Cognition and the Brief Assessment of Impaired Cognition Questionnaire for identification of mild cognitive impairment in a memory clinic setting

AU - Jørgensen, Kasper

AU - Nielsen, Thomas R

AU - Nielsen, Ann

AU - Waldorff, Frans B

AU - Waldemar, Gunhild

N1 - © 2020 The Authors. International Journal of Geriatric Psychiatry published by John Wiley & Sons Ltd.

PY - 2020/8

Y1 - 2020/8

N2 - OBJECTIVES: The aim of this study was to validate the Brief Assessment of Impaired Cognition (BASIC) and the Brief Assessment of Impaired Cognition Questionnaire (BASIC-Q) for identification of mild cognitive impairment (MCI) in a memory clinic setting.METHODS: A total of 163 sociodemographically matched patients (MCI, n = 42, and dementia, n = 121) and 83 control participants were included in the study. Two instruments were validated: (a) BASIC, including the components self-report, informant report, and two brief cognitive tests, and (b) BASIC-Q, including the components self-report, informant report, and orientation. BASIC can be administered in 5 minutes and BASIC-Q in less than 5 minutes.RESULTS: A high discriminative validity for MCI vs control participants was found for both BASIC (sensitivity 0.86, specificity 0.89) and BASIC-Q (sensitivity 0.88, specificity 0.88). In comparison, the MMSE had low sensitivity (0.61) and moderate specificity (0.72). All components of BASIC and BASIC-Q contributed significantly to differentiate MCI from control participants. The components of BASIC and BASIC-Q also contributed significantly to differentiate MCI from dementia, except for self-report, which was identical in the two groups.CONCLUSIONS: Both BASIC and BASIC-Q are brief, valid, and effective instruments for identification of patients with possible MCI in a memory clinic setting. Further cross-validation of the instruments in a general practice or primary care setting is needed.

AB - OBJECTIVES: The aim of this study was to validate the Brief Assessment of Impaired Cognition (BASIC) and the Brief Assessment of Impaired Cognition Questionnaire (BASIC-Q) for identification of mild cognitive impairment (MCI) in a memory clinic setting.METHODS: A total of 163 sociodemographically matched patients (MCI, n = 42, and dementia, n = 121) and 83 control participants were included in the study. Two instruments were validated: (a) BASIC, including the components self-report, informant report, and two brief cognitive tests, and (b) BASIC-Q, including the components self-report, informant report, and orientation. BASIC can be administered in 5 minutes and BASIC-Q in less than 5 minutes.RESULTS: A high discriminative validity for MCI vs control participants was found for both BASIC (sensitivity 0.86, specificity 0.89) and BASIC-Q (sensitivity 0.88, specificity 0.88). In comparison, the MMSE had low sensitivity (0.61) and moderate specificity (0.72). All components of BASIC and BASIC-Q contributed significantly to differentiate MCI from control participants. The components of BASIC and BASIC-Q also contributed significantly to differentiate MCI from dementia, except for self-report, which was identical in the two groups.CONCLUSIONS: Both BASIC and BASIC-Q are brief, valid, and effective instruments for identification of patients with possible MCI in a memory clinic setting. Further cross-validation of the instruments in a general practice or primary care setting is needed.

KW - BASIC

KW - BASIC-Q

KW - cognitive assessment

KW - cognitive screening

KW - dementia

KW - diagnostic accuracy

KW - discriminative validity

KW - mild cognitive impairment

KW - predictive validity

UR - http://www.scopus.com/inward/record.url?scp=85084139553&partnerID=8YFLogxK

U2 - 10.1002/gps.5312

DO - 10.1002/gps.5312

M3 - Journal article

C2 - 32291812

VL - 35

SP - 907

EP - 915

JO - International Journal of Geriatric Psychiatry

JF - International Journal of Geriatric Psychiatry

SN - 0885-6230

IS - 8

ER -

ID: 61263618