Vaccination ved organtransplantation

Sebastian Rask Hamm; Christina Ekenberg; Hans Henrik Lawaetz Schultz; Lykke Larsen; Karin Skov; Marie Helleberg; Søren Jensen-Fangel; Zitta Barrella Harboe; Carsten Schade Larsen; Susanne Dam Nielsen

doi:10.61409/V03250242

Vaccination ved organtransplantation

Translated title of the contribution: Vaccination in solid organ transplantation

Sebastian Rask Hamm, Christina Ekenberg, Hans Henrik Lawaetz Schultz, Lykke Larsen, Karin Skov, Marie Helleberg, Søren Jensen-Fangel, Zitta Barrella Harboe, Carsten Schade Larsen, Susanne Dam Nielsen^*

^*Corresponding author for this work

Abstract

Solid organ transplant (SOT) recipients receive maintenance immunosuppressive therapy and are at risk of infections and severe infection-related disease. Despite weaker immunological responses to vaccines in SOT recipients compared to controls, this review finds that vaccination has been associated with a lower risk of severe disease, and vaccination before transplantation is recommended in international and Danish guidelines. A national programme for vaccination of SOT candidates has been implemented in Denmark, and vaccination coverage is high for patients participating in the programme.

Translated title of the contribution	Vaccination in solid organ transplantation
Original language	Danish
Article number	V03250242
Journal	Ugeskrift for Laeger
Volume	187
Issue number	46
Pages (from-to)	1-9
Number of pages	9
ISSN	0041-5782
DOIs	https://doi.org/10.61409/V03250242
Publication status	Published - 10 Nov 2025

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10.61409/V03250242

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title = "Vaccination ved organtransplantation",

abstract = "Solid organ transplant (SOT) recipients receive maintenance immunosuppressive therapy and are at risk of infections and severe infection-related disease. Despite weaker immunological responses to vaccines in SOT recipients compared to controls, this review finds that vaccination has been associated with a lower risk of severe disease, and vaccination before transplantation is recommended in international and Danish guidelines. A national programme for vaccination of SOT candidates has been implemented in Denmark, and vaccination coverage is high for patients participating in the programme.",

keywords = "Humans, Organ Transplantation, Vaccination, Denmark, Immunosuppressive Agents/adverse effects, Practice Guidelines as Topic",

author = "Hamm, \{Sebastian Rask\} and Christina Ekenberg and Schultz, \{Hans Henrik Lawaetz\} and Lykke Larsen and Karin Skov and Marie Helleberg and S{\o}ren Jensen-Fangel and Harboe, \{Zitta Barrella\} and Larsen, \{Carsten Schade\} and Nielsen, \{Susanne Dam\}",

note = "Published under Open Access CC-BY-NC-BD 4.0. https://creativecommons.org/licenses/by-nc-nd/4.0/.",

year = "2025",

month = nov,

day = "10",

doi = "10.61409/V03250242",

language = "Dansk",

volume = "187",

pages = "1--9",

journal = "Ugeskrift for Laeger",

issn = "0041-5782",

publisher = "Almindelige Danske Laegeforening",

number = "46",

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TY - JOUR

T1 - Vaccination ved organtransplantation

AU - Hamm, Sebastian Rask

AU - Ekenberg, Christina

AU - Schultz, Hans Henrik Lawaetz

AU - Larsen, Lykke

AU - Skov, Karin

AU - Helleberg, Marie

AU - Jensen-Fangel, Søren

AU - Harboe, Zitta Barrella

AU - Larsen, Carsten Schade

AU - Nielsen, Susanne Dam

N1 - Published under Open Access CC-BY-NC-BD 4.0. https://creativecommons.org/licenses/by-nc-nd/4.0/.

PY - 2025/11/10

Y1 - 2025/11/10

N2 - Solid organ transplant (SOT) recipients receive maintenance immunosuppressive therapy and are at risk of infections and severe infection-related disease. Despite weaker immunological responses to vaccines in SOT recipients compared to controls, this review finds that vaccination has been associated with a lower risk of severe disease, and vaccination before transplantation is recommended in international and Danish guidelines. A national programme for vaccination of SOT candidates has been implemented in Denmark, and vaccination coverage is high for patients participating in the programme.

AB - Solid organ transplant (SOT) recipients receive maintenance immunosuppressive therapy and are at risk of infections and severe infection-related disease. Despite weaker immunological responses to vaccines in SOT recipients compared to controls, this review finds that vaccination has been associated with a lower risk of severe disease, and vaccination before transplantation is recommended in international and Danish guidelines. A national programme for vaccination of SOT candidates has been implemented in Denmark, and vaccination coverage is high for patients participating in the programme.

KW - Humans

KW - Organ Transplantation

KW - Vaccination

KW - Denmark

KW - Immunosuppressive Agents/adverse effects

KW - Practice Guidelines as Topic

UR - https://www.scopus.com/pages/publications/105022521610

U2 - 10.61409/V03250242

DO - 10.61409/V03250242

M3 - Review

C2 - 41268996

SN - 0041-5782

VL - 187

SP - 1

EP - 9

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

IS - 46

M1 - V03250242

ER -

Vaccination ved organtransplantation

Abstract

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