Using genetic loci to understand the relationship between adiposity and psychological distress: a Mendelian Randomization study in the Copenhagen General Population Study of 53,221 adults

Debbie A Lawlor; Roger M Harbord; Anne  Tybjærg-Hansen; Tom M Palmer; Jeppe Zacho; Marianne Benn; Nicholas J Timpson; George Davey Smith; Børge G Nordestgaard

doi:10.1111/j.1365-2796.2011.02343.x

Using genetic loci to understand the relationship between adiposity and psychological distress: a Mendelian Randomization study in the Copenhagen General Population Study of 53,221 adults

Debbie A Lawlor
, Roger M Harbord
, Anne Tybjærg-Hansen
, Tom M Palmer
, Jeppe Zacho
, Marianne Benn
, Nicholas J Timpson
, George Davey Smith
, Børge G Nordestgaard

Department of Clinical Biochemistry

60 Citations (Scopus)

Abstract

We used genetic variants that are robustly associated with adiposity to examine the causal association of adiposity with psychological distress.

Original language	English
Journal	Journal of Internal Medicine
Volume	269
Issue number	5
Pages (from-to)	525-37
Number of pages	13
ISSN	0954-6820
DOIs	https://doi.org/10.1111/j.1365-2796.2011.02343.x
Publication status	Published - 2011

Keywords

Adiposity
Adult
Aged
Aged, 80 and over
Anxiety Disorders
Body Mass Index
Cohort Studies
Cross-Sectional Studies
Denmark
Female
Genetic Loci
Genotype
Humans
Male
Mendelian Randomization Analysis
Middle Aged
Proteins
Receptor, Melanocortin, Type 4
Risk Factors
Stress, Psychological
Waist-Hip Ratio
Young Adult

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10.1111/j.1365-2796.2011.02343.x

Cite this

Lawlor, D. A., Harbord, R. M., Tybjærg-Hansen, A., Palmer, T. M., Zacho, J., Benn, M., Timpson, N. J., Smith, G. D., & Nordestgaard, B. G. (2011). Using genetic loci to understand the relationship between adiposity and psychological distress: a Mendelian Randomization study in the Copenhagen General Population Study of 53,221 adults. Journal of Internal Medicine, 269(5), 525-37. https://doi.org/10.1111/j.1365-2796.2011.02343.x

Using genetic loci to understand the relationship between adiposity and psychological distress: a Mendelian Randomization study in the Copenhagen General Population Study of 53,221 adults. / Lawlor, Debbie A; Harbord, Roger M; Tybjærg-Hansen, Anne et al.
In: Journal of Internal Medicine, Vol. 269, No. 5, 2011, p. 525-37.

Research output: Contribution to journal › Journal article › Research › peer-review

Lawlor, DA, Harbord, RM, Tybjærg-Hansen, A, Palmer, TM, Zacho, J, Benn, M, Timpson, NJ, Smith, GD & Nordestgaard, BG 2011, 'Using genetic loci to understand the relationship between adiposity and psychological distress: a Mendelian Randomization study in the Copenhagen General Population Study of 53,221 adults', Journal of Internal Medicine, vol. 269, no. 5, pp. 525-37. https://doi.org/10.1111/j.1365-2796.2011.02343.x

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abstract = "We used genetic variants that are robustly associated with adiposity to examine the causal association of adiposity with psychological distress.",

keywords = "Adiposity, Adult, Aged, Aged, 80 and over, Anxiety Disorders, Body Mass Index, Cohort Studies, Cross-Sectional Studies, Denmark, Female, Genetic Loci, Genotype, Humans, Male, Mendelian Randomization Analysis, Middle Aged, Proteins, Receptor, Melanocortin, Type 4, Risk Factors, Stress, Psychological, Waist-Hip Ratio, Young Adult",

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AU - Palmer, Tom M

AU - Zacho, Jeppe

AU - Benn, Marianne

AU - Timpson, Nicholas J

AU - Smith, George Davey

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KW - Cross-Sectional Studies

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Using genetic loci to understand the relationship between adiposity and psychological distress: a Mendelian Randomization study in the Copenhagen General Population Study of 53,221 adults

Abstract

Keywords

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